8DL7
Cryo-EM structure of human ferroportin/slc40 bound to minihepcidin PR73 in nanodisc
Summary for 8DL7
Entry DOI | 10.2210/pdb8dl7/pdb |
EMDB information | 27498 |
Related PRD ID | PRD_002510 |
Descriptor | Solute carrier family 40 member 1, 11F9 light-chain, 11F9 heavy-chain, ... (6 entities in total) |
Functional Keywords | slc40, fpn, ferroportin, iron, transporter, hepcidin, minihepcidin, pr73, human, nanodisc, membrane protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 115951.90 |
Authors | Shen, J.,Wilbon, A.S.,Pan, Y.,Zhou, M. (deposition date: 2022-07-07, release date: 2022-12-07, Last modification date: 2023-11-15) |
Primary citation | Wilbon, A.S.,Shen, J.,Ruchala, P.,Zhou, M.,Pan, Y. Structural basis of ferroportin inhibition by minihepcidin PR73. Plos Biol., 21:e3001936-e3001936, 2023 Cited by PubMed: 36649314DOI: 10.1371/journal.pbio.3001936 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.7 Å) |
Structure validation
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