8DL7
Cryo-EM structure of human ferroportin/slc40 bound to minihepcidin PR73 in nanodisc
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Solute carrier family 40 member 1 | polymer | 577 | 63386.6 | 1 | UniProt (Q9NP59) Pfam (PF06963) | Homo sapiens (human) | Ferroportin-1,Iron-regulated transporter 1 |
| 2 | B (C) | 11F9 light-chain | polymer | 213 | 23493.9 | 1 | Mus musculus (mouse) | ||
| 3 | C (D) | 11F9 heavy-chain | polymer | 238 | 25815.0 | 1 | Mus musculus (mouse) | ||
| 4 | D (F) | Minihepcidin PR73 | polymer | 12 | 1736.2 | 1 | BIRD (PRD_002510) | synthetic construct | |
| 5 | E, F (A) | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate | non-polymer | 760.1 | 2 | Chemie (POV) | |||
| 6 | G (D) | water | water | 18.0 | 1 | Chemie (HOH) |
Sequence modifications
A: 1 - 571 (UniProt: Q9NP59)
| PDB | External Database | Details |
|---|---|---|
| Glu 572 | - | expression tag |
| Asn 573 | - | expression tag |
| Leu 574 | - | expression tag |
| Tyr 575 | - | expression tag |
| Phe 576 | - | expression tag |
| Gln 577 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 114431.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1520.2 | |
| All* | Total formula weight | 115951.9 |
