1D1N
 
 | | SOLUTION STRUCTURE OF THE FMET-TRNAFMET BINDING DOMAIN OF BECILLUS STEAROTHERMOPHILLUS TRANSLATION INITIATION FACTOR IF2 | | 分子名称: | INITIATION FACTOR 2 | | 著者 | Meunier, S, Spurio, S, Czisch, M, Wechselberger, R, Gueunneugues, M. | | 登録日 | 1999-09-20 | | 公開日 | 2000-09-20 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of the fMet-tRNA(fMet)-binding domain of B. stearothermophilus initiation factor IF2.
EMBO J., 19, 2000
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3E1Y
 | | Crystal structure of human eRF1/eRF3 complex | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Eukaryotic peptide chain release factor GTP-binding subunit ERF3A, Eukaryotic peptide chain release factor subunit 1 | | 著者 | Cheng, Z, Lim, M, Kong, C, Song, H. | | 登録日 | 2008-08-05 | | 公開日 | 2009-05-19 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | | 主引用文献 | Structural insights into eRF3 and stop codon recognition by eRF1
Genes Dev., 23, 2009
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1EFM
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2FX3
 | | Crystal Structure Determination of E. coli Elongation Factor, Tu using a Twinned Data Set | | 分子名称: | Elongation factor Tu, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | | 著者 | Heffron, S.E, Moeller, R, Jurnak, F. | | 登録日 | 2006-02-03 | | 公開日 | 2006-03-28 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Solving the structure of Escherichia coli elongation factor Tu using a twinned data set.
Acta Crystallogr.,Sect.D, 62, 2006
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2RDO
 | | 50S subunit with EF-G(GDPNP) and RRF bound | | 分子名称: | 23S RIBOSOMAL RNA, 50S ribosomal protein L1, 50S ribosomal protein L11, ... | | 著者 | Gao, N, Zavialov, A.V, Ehrenberg, M, Frank, J. | | 登録日 | 2007-09-24 | | 公開日 | 2008-03-04 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (9.1 Å) | | 主引用文献 | Specific interaction between EF-G and RRF and its implication for GTP-dependent ribosome splitting into subunits.
J.Mol.Biol., 374, 2007
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6XK9
 | | Cereblon in complex with DDB1, CC-90009, and GSPT1 | | 分子名称: | 2-(4-chlorophenyl)-N-({2-[(3S)-2,6-dioxopiperidin-3-yl]-1-oxo-2,3-dihydro-1H-isoindol-5-yl}methyl)-2,2-difluoroacetamide, DNA damage-binding protein 1, Eukaryotic peptide chain release factor GTP-binding subunit ERF3A, ... | | 著者 | Clayton, T.L, Tran, E.T, Zhu, J, Pagarigan, B.E, Matyskiela, M.E, Chamberlain, P.P. | | 登録日 | 2020-06-25 | | 公開日 | 2020-12-02 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.64 Å) | | 主引用文献 | CC-90009, a novel cereblon E3 ligase modulator, targets acute myeloid leukemia blasts and leukemia stem cells.
Blood, 137, 2021
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1N0V
 | | Crystal structure of elongation factor 2 | | 分子名称: | Elongation factor 2 | | 著者 | Joergensen, R, Ortiz, P.A, Carr-Schmid, A, Nissen, P, Kinzy, T.G, Andersen, G.R. | | 登録日 | 2002-10-15 | | 公開日 | 2002-11-27 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Two crystal structures demonstrate large conformational changes in the eukaryotic ribosomal translocase.
Nat.Struct.Biol., 10, 2003
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6RA9
 | | Novel structural features and post-translational modifications in eukaryotic elongation factor 1A2 from Oryctolagus cuniculus | | 分子名称: | Elongation factor 1-alpha 2, GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, ... | | 著者 | Carriles, A.A, Hermoso, J, Gago, F. | | 登録日 | 2019-04-05 | | 公開日 | 2020-06-03 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural Cues for Understanding eEF1A2 Moonlighting.
Chembiochem, 22, 2021
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3MMP
 | | Structure of the Qb replicase, an RNA-dependent RNA polymerase consisting of viral and host proteins | | 分子名称: | (2S)-1-[3-{[(2R)-2-hydroxypropyl]oxy}-2,2-bis({[(2R)-2-hydroxypropyl]oxy}methyl)propoxy]propan-2-ol, Elongation factor Tu 2, Elongation factor Ts, ... | | 著者 | Kidmose, R.T, Vasiliev, N.N, Chetverin, A.B, Knudsen, C.R, Andersen, G.R. | | 登録日 | 2010-04-20 | | 公開日 | 2010-06-09 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure of the Qbeta replicase, an RNA-dependent RNA polymerase consisting of viral and host proteins.
Proc.Natl.Acad.Sci.USA, 107, 2010
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7UG7
 | | 70S ribosome complex in an intermediate state of translocation bound to EF-G(GDP) stalled by Argyrin B | | 分子名称: | 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ... | | 著者 | Rundlet, E.J, Wieland, M, Holm, M, Koller, T.O, Blanchard, S.C, Wilson, D.N. | | 登録日 | 2022-03-24 | | 公開日 | 2022-05-18 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (2.58 Å) | | 主引用文献 | The cyclic octapeptide antibiotic argyrin B inhibits translation by trapping EF-G on the ribosome during translocation.
Proc.Natl.Acad.Sci.USA, 119, 2022
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4V9K
 | | 70S ribosome translocation intermediate GDPNP-I containing elongation factor EFG/GDPNP, mRNA, and tRNA bound in the pe*/E state. | | 分子名称: | 23S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | | 著者 | Zhou, J, Lancaster, L, Donohue, J.P, Noller, H.F. | | 登録日 | 2013-04-24 | | 公開日 | 2014-07-09 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Crystal structures of EF-G-ribosome complexes trapped in intermediate states of translocation.
Science, 340, 2013
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4V5L
 | | The structure of EF-Tu and aminoacyl-tRNA bound to the 70S ribosome with a GTP analog | | 分子名称: | 16S RRNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ... | | 著者 | Voorhees, R.M, Schmeing, T.M, Ramakrishnan, V. | | 登録日 | 2010-09-02 | | 公開日 | 2014-07-09 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | The Mechanism for Activation of GTP Hydrolysis on the Ribosome.
Science, 330, 2010
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3VNV
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4G5G
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4Q7J
 | | Complex structure of viral RNA polymerase | | 分子名称: | 30S ribosomal protein S1, Elongation factor Ts, Elongation factor Tu 1, ... | | 著者 | Takeshita, D. | | 登録日 | 2014-04-25 | | 公開日 | 2014-08-27 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Molecular insights into replication initiation by Q beta replicase using ribosomal protein S1.
Nucleic Acids Res., 42, 2014
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4FWT
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5HXB
 | | Cereblon in complex with DDB1, CC-885, and GSPT1 | | 分子名称: | 1-(3-chloro-4-methylphenyl)-3-({2-[(3S)-2,6-dioxopiperidin-3-yl]-1-oxo-2,3-dihydro-1H-isoindol-5-yl}methyl)urea, DNA damage-binding protein 1, Eukaryotic peptide chain release factor GTP-binding subunit ERF3A, ... | | 著者 | Chamberlain, P.P, Matyskiela, M, Pagarigan, B. | | 登録日 | 2016-01-30 | | 公開日 | 2016-06-29 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | A novel cereblon modulator recruits GSPT1 to the CRL4(CRBN) ubiquitin ligase.
Nature, 535, 2016
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7N2C
 | | Elongating 70S ribosome complex in a fusidic acid-stalled intermediate state of translocation bound to EF-G(GDP) (INT2) | | 分子名称: | 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ... | | 著者 | Rundlet, E.J, Holm, M, Schacherl, M, Natchiar, K.S, Altman, R.B, Spahn, C.M.T, Myasnikov, A.G, Blanchard, S.C. | | 登録日 | 2021-05-28 | | 公開日 | 2021-07-14 | | 最終更新日 | 2021-08-11 | | 実験手法 | ELECTRON MICROSCOPY (2.72 Å) | | 主引用文献 | Structural basis of early translocation events on the ribosome.
Nature, 595, 2021
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7N2V
 | | Elongating 70S ribosome complex in a spectinomycin-stalled intermediate state of translocation bound to EF-G in an active, GTP conformation (INT1) | | 分子名称: | 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ... | | 著者 | Rundlet, E.J, Holm, M, Schacherl, M, Natchiar, K.S, Altman, R.B, Spahn, C.M.T, Myasnikov, A.G, Blanchard, S.C. | | 登録日 | 2021-05-29 | | 公開日 | 2021-07-14 | | 最終更新日 | 2021-08-11 | | 実験手法 | ELECTRON MICROSCOPY (2.54 Å) | | 主引用文献 | Structural basis of early translocation events on the ribosome.
Nature, 595, 2021
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5I4Q
 | | Contact-dependent inhibition system from Escherichia coli NC101 - ternary CdiA/CdiI/EF-Tu complex (domains 2 and 3) | | 分子名称: | CHLORIDE ION, Contact-dependent inhibitor A, Contact-dependent inhibitor I, ... | | 著者 | Michalska, K, Stols, L, Eschenfeldt, W, Hayes, C.S, Goulding, C.W, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes (UC4CDI) | | 登録日 | 2016-02-12 | | 公開日 | 2017-06-28 | | 最終更新日 | 2019-12-25 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Structure of a novel antibacterial toxin that exploits elongation factor Tu to cleave specific transfer RNAs.
Nucleic Acids Res., 45, 2017
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3VNU
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4R71
 | | Structure of the Qbeta holoenzyme complex in the P1211 crystal form | | 分子名称: | 30S ribosomal protein S1, Elongation factor Ts, Elongation factor Tu, ... | | 著者 | Gytz, H, Seweryn, P, Kutlubaeva, Z, Chetverin, A.B, Brodersen, D.E, Knudsen, C.R. | | 登録日 | 2014-08-26 | | 公開日 | 2015-09-23 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.21 Å) | | 主引用文献 | Structural basis for RNA-genome recognition during bacteriophage Q beta replication.
Nucleic Acids Res., 43, 2015
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2XEX
 | | crystal structure of Staphylococcus aureus elongation factor G | | 分子名称: | CHLORIDE ION, ELONGATION FACTOR G, POTASSIUM ION | | 著者 | Chen, Y, Koripella, R.K, Sanyal, S, Selmer, M. | | 登録日 | 2010-05-19 | | 公開日 | 2010-07-14 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Staphylococcus Aureus Elongation Factor G - Structure and Analysis of a Target for Fusidic Acid.
FEBS J., 277, 2010
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2YWH
 | | Crystal structure of GDP-bound LepA from Aquifex aeolicus | | 分子名称: | GTP-binding protein LepA, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | | 著者 | Kawazoe, M, Takemoto, C, Kaminishi, T, Nishino, A, Nakayama-Ushikoshi, R, Hanawa-Suetsugu, K, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2007-04-20 | | 公開日 | 2008-04-29 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | | 主引用文献 | Crystal structures of GTP-binding protein LepA from Aquifex aeolicus.
To be Published
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5WFS
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