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PDB: 156 件

1QFL
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BIOSYNTHETIC THIOLASE FROM ZOOGLOEA RAMIGERA IN COMPLEX WITH A REACTION INTERMEDIATE.
分子名称: COENZYME A, PROTEIN (ACETOACETYL-COA THIOLASE), SULFATE ION
著者Modis, Y, Wierenga, R.K.
登録日1999-04-12
公開日2000-04-19
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献A biosynthetic thiolase in complex with a reaction intermediate: the crystal structure provides new insights into the catalytic mechanism.
Structure Fold.Des., 7, 1999
2D3T
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Fatty Acid beta-oxidation multienzyme complex from Pseudomonas Fragi, Form V
分子名称: 3-ketoacyl-CoA thiolase, ACETYL COENZYME *A, Fatty oxidation complex alpha subunit, ...
著者Tsuchiya, D, Shimizu, N, Ishikawa, M, Suzuki, Y, Morikawa, K.
登録日2005-10-01
公開日2006-02-21
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Ligand-Induced Domain Rearrangement of Fatty Acid beta-Oxidation Multienzyme Complex
Structure, 14, 2006
1WDL
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fatty acid beta-oxidation multienzyme complex from Pseudomonas fragi, form II (native4)
分子名称: 3,6,9,12,15-PENTAOXATRICOSAN-1-OL, 3-ketoacyl-CoA thiolase, ACETYL COENZYME *A, ...
著者Ishikawa, M, Tsuchiya, D, Oyama, T, Tsunaka, Y, Morikawa, K.
登録日2004-05-17
公開日2004-07-27
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structural basis for channelling mechanism of a fatty acid beta-oxidation multienzyme complex
Embo J., 23, 2004
1WDK
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fatty acid beta-oxidation multienzyme complex from Pseudomonas fragi, form I (native2)
分子名称: 3,6,9,12,15-PENTAOXATRICOSAN-1-OL, 3-ketoacyl-CoA thiolase, ACETYL COENZYME *A, ...
著者Ishikawa, M, Tsuchiya, D, Oyama, T, Tsunaka, Y, Morikawa, K.
登録日2004-05-17
公開日2004-07-27
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis for channelling mechanism of a fatty acid beta-oxidation multienzyme complex
Embo J., 23, 2004
1WDM
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fatty acid beta-oxidation multienzyme complex from Pseudomonas fragi, form I (native3)
分子名称: 3-ketoacyl-CoA thiolase, ACETYL COENZYME *A, Fatty oxidation complex alpha subunit, ...
著者Ishikawa, M, Tsuchiya, D, Oyama, T, Tsunaka, Y, Morikawa, K.
登録日2004-05-17
公開日2004-07-27
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Structural basis for channelling mechanism of a fatty acid beta-oxidation multienzyme complex
Embo J., 23, 2004
1WL4
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Human cytosolic acetoacetyl-CoA thiolase complexed with CoA
分子名称: COENZYME A, GLYCEROL, SULFATE ION, ...
著者Kursula, P, Fukao, T, Kondo, N, Wierenga, R.K.
登録日2004-06-20
公開日2005-03-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献High Resolution Crystal Structures of Human Cytosolic Thiolase (CT): A Comparison of the Active Sites of Human CT, Bacterial Thiolase, and Bacterial KAS I
J.Mol.Biol., 347, 2005
4WYS
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Crystal structure of thiolase from Escherichia coli
分子名称: Acetyl-CoA acetyltransferase
著者Kim, S, Ha, S.C, Ahn, J.W, Kim, E.J, Lim, J.H, Kim, K.J.
登録日2014-11-18
公開日2015-10-07
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Redox-switch regulatory mechanism of thiolase from Clostridium acetobutylicum
Nat Commun, 6, 2015
1WL5
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Human cytosolic acetoacetyl-CoA thiolase
分子名称: GLYCEROL, SULFATE ION, acetyl-Coenzyme A acetyltransferase 2
著者Kursula, P, Fukao, T, Kondo, N, Wierenga, R.K.
登録日2004-06-20
公開日2005-03-01
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献High Resolution Crystal Structures of Human Cytosolic Thiolase (CT): A Comparison of the Active Sites of Human CT, Bacterial Thiolase, and Bacterial KAS I
J.Mol.Biol., 347, 2005
4WYR
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Crystal structure of thiolase mutation (V77Q,N153Y,A286K) from Clostridium acetobutylicum
分子名称: Acetyl-CoA acetyltransferase, DI(HYDROXYETHYL)ETHER, GLYCEROL
著者Kim, S, Ha, S.C, Ahn, J.W, Kim, E.J, Lim, J.H, Kim, K.J.
登録日2014-11-18
公開日2015-10-07
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Redox-switch regulatory mechanism of thiolase from Clostridium acetobutylicum
Nat Commun, 6, 2015
4XL4
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Crystal structure of thiolase from Clostridium acetobutylicum in complex with CoA
分子名称: Acetyl-CoA acetyltransferase, COENZYME A, GLYCEROL
著者Kim, S, Ha, S.C, Ahn, J.W, Kim, E.J, Lim, J.H, Kim, K.J.
登録日2015-01-13
公開日2015-10-07
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Redox-switch regulatory mechanism of thiolase from Clostridium acetobutylicum
Nat Commun, 6, 2015
4XL2
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Crystal structure of oxidized form of thiolase from Clostridium acetobutylicum
分子名称: ACETATE ION, Acetyl-CoA acetyltransferase, DI(HYDROXYETHYL)ETHER, ...
著者Kim, S, Ha, S.C, Ahn, J.W, Kim, E.J, Lim, J.H, Kim, K.J.
登録日2015-01-13
公開日2015-10-07
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Redox-switch regulatory mechanism of thiolase from Clostridium acetobutylicum
Nat Commun, 6, 2015
4XL3
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Crystal structure of reduced form of thiolase from Clostridium acetobutylicum
分子名称: Acetyl-CoA acetyltransferase, GLYCEROL
著者Kim, S, Ha, S.C, Ahn, J.W, Kim, E.J, Lim, J.H, Kim, K.J.
登録日2015-01-13
公開日2015-10-07
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Redox-switch regulatory mechanism of thiolase from Clostridium acetobutylicum
Nat Commun, 6, 2015
1M3Z
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Biosynthetic thiolase, C89A mutant, complexed with acetyl coenzyme A
分子名称: ACETYL COENZYME *A, Acetyl-CoA acetyltransferase, SULFATE ION
著者Kursula, P, Ojala, J, Lambeir, A.-M, Wierenga, R.K.
登録日2002-07-03
公開日2002-11-29
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献The catalytic cycle of biosynthetic thiolase: A conformational journey of an acetyl group through four binding modes and two oxyanion holes
Biochemistry, 41, 2002
1M1T
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Biosynthetic thiolase, Q64A mutant
分子名称: Acetyl-CoA acetyltransferase, GLYCEROL, SULFATE ION
著者Kursula, P, Ojala, J, Lambeir, A.-M, Wierenga, R.K.
登録日2002-06-20
公開日2002-11-29
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献The catalytic cycle of biosynthetic thiolase: A conformational journey of an acetyl group through four binding modes and two oxyanion holes
Biochemistry, 41, 2002
1M4S
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BU of 1m4s by Molmil
Biosynthetic thiolase, Cys89 acetylated, unliganded form
分子名称: Acetyl-CoA acetyltransferase, GLYCEROL, SULFATE ION
著者Kursula, P, Ojala, J, Lambeir, A.-M, Wierenga, R.K.
登録日2002-07-03
公開日2002-11-29
最終更新日2018-03-07
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献The catalytic cycle of biosynthetic thiolase: A conformational journey of an acetyl group through four binding modes and two oxyanion holes
Biochemistry, 41, 2002
1M1O
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Crystal structure of biosynthetic thiolase, C89A mutant, complexed with acetoacetyl-CoA
分子名称: ACETOACETYL-COENZYME A, Acetyl-CoA acetyltransferase, SULFATE ION
著者Kursula, P, Ojala, J, Lambeir, A.-M, Wierenga, R.K.
登録日2002-06-20
公開日2002-11-29
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献The catalytic cycle of biosynthetic thiolase: A conformational journey of an acetyl group through four binding modes and two oxyanion holes
Biochemistry, 41, 2002
1M4T
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Biosynthetic thiolase, Cys89 butyrylated
分子名称: Acetyl-CoA acetyltransferase, GLYCEROL, SULFATE ION
著者Kursula, P, Ojala, J, Lambeir, A.-M, Wierenga, R.K.
登録日2002-07-03
公開日2002-11-29
最終更新日2018-03-07
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献The catalytic cycle of biosynthetic thiolase: A conformational journey of an acetyl group through four binding modes and two oxyanion holes
Biochemistry, 41, 2002
4C2K
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Crystal structure of human mitochondrial 3-ketoacyl-CoA thiolase
分子名称: 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ...
著者Kiema, T.-R, Harijan, R.K, Wierenga, R.K.
登録日2013-08-19
公開日2014-09-03
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The Crystal Structure of Human Mitochondrial 3-Ketoacyl-Coa Thiolase (T1): Insight Into the Reaction Mechanism of its Thiolase and Thioesterase Activities
Acta Crystallogr.,Sect.D, 70, 2014
4C2J
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Crystal structure of human mitochondrial 3-ketoacyl-CoA thiolase in complex with CoA
分子名称: 1,2-ETHANEDIOL, 3-KETOACYL-COA THIOLASE, MITOCHONDRIAL, ...
著者Kiema, T.-R, Harijan, R.K, Wierenga, R.K.
登録日2013-08-19
公開日2014-09-03
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The Crystal Structure of Human Mitochondrial 3-Ketoacyl-Coa Thiolase (T1): Insight Into the Reaction Mechanism of its Thiolase and Thioesterase Activities
Acta Crystallogr.,Sect.D, 70, 2014
4B3H
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Crystal structure of Mycobacterium tuberculosis fatty acid beta- oxidation complex
分子名称: FATTY ACID BETA-OXIDATION COMPLEX ALPHA-CHAIN FADB, FATTY ACID BETA-OXIDATION COMPLEX BETA-CHAIN FADA, GLYCEROL, ...
著者Venkatesan, R, Wierenga, R.
登録日2012-07-24
公開日2013-03-27
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of Mycobacterial Beta-Oxidation Trifunctional Enzyme Reveals its Altered Assembly and Putative Substrate Channeling Pathway.
Acs Chem.Biol., 8, 2013
2IB8
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Crystallographic and kinetic studies of human mitochondrial acetoacetyl-CoA thiolase (T2): the importance of potassium and chloride for its structure and function
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Acetyl-CoA acetyltransferase, CHLORIDE ION, ...
著者Haapalainen, A.M, Wierenga, R.K.
登録日2006-09-11
公開日2007-04-03
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystallographic and Kinetic Studies of Human Mitochondrial Acetoacetyl-CoA Thiolase: The Importance of Potassium and Chloride Ions for Its Structure and Function
Biochemistry, 46, 2007
2IBU
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Crystallographic and kinetic studies of human mitochondrial acetoacetyl-CoA thiolase (T2): the importance of potassium and chloride for its structure and function
分子名称: Acetyl-CoA acetyltransferase, CHLORIDE ION, COENZYME A, ...
著者Haapalainen, A.M, Wierenga, R.K.
登録日2006-09-12
公開日2007-04-03
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystallographic and Kinetic Studies of Human Mitochondrial Acetoacetyl-CoA Thiolase: The Importance of Potassium and Chloride Ions for Its Structure and Function
Biochemistry, 46, 2007
2IBW
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Crystallographic and kinetic studies of human mitochondrial acetoacetyl-CoA thiolase (T2): the importance of potassium and chloride for its structure and function
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Acetyl-CoA acetyltransferase, CHLORIDE ION, ...
著者Haapalainen, A.M, Wierenga, R.K.
登録日2006-09-12
公開日2007-04-03
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystallographic and Kinetic Studies of Human Mitochondrial Acetoacetyl-CoA Thiolase: The Importance of Potassium and Chloride Ions for Its Structure and Function
Biochemistry, 46, 2007
2IIK
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Crystal Structure of human peroxisomal acetyl-CoA acyl transferase 1 (ACAA1)
分子名称: 3-ketoacyl-CoA thiolase, peroxisomal
著者Papagrigoriou, E, Johansson, C, Smee, C, Kavanagh, K, Pike, A.C.W, Sundstrom, M, Weigelt, J, Edwards, A, Arrowsmith, C.H, Gileadi, O, Gorrec, F, Umeano, C, von Delft, F, Oppermann, U, Structural Genomics Consortium (SGC)
登録日2006-09-28
公開日2006-10-10
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Crystal Structure of human peroxisomal acetyl-CoA acyl transferase 1 (ACAA1)
TO BE PUBLISHED
4E1L
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Crystal structure of Acetoacetyl-CoA thiolase (thlA2) from Clostridium difficile
分子名称: Acetoacetyl-CoA thiolase 2, IODIDE ION
著者Anderson, S.M, Wawrzak, Z, Kudritska, M, Peterson, S.N, Anderson, W.F, Savchenko, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2012-03-06
公開日2012-03-21
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献

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