1M4S

Biosynthetic thiolase, Cys89 acetylated, unliganded form

Summary for 1M4S

• Entry DOI: 10.2210/pdb1m4s/pdb
• Related: 1DLU 1DLV 1DM3 1M1O 1M1T 1M3Z 1M4T 1QFL
• Descriptor: Acetyl-CoA acetyltransferase, SULFATE ION, GLYCEROL, ... (4 entities in total)
• Functional Keywords: thiolase fold, acetylated intermediate, transferase
• Biological source: Zoogloea ramigera
• Cellular location: Cytoplasm: P07097
• Total number of polymer chains: 4
• Total formula weight: 163085.61

Authors

Kursula, P.,Ojala, J.,Lambeir, A.-M.,Wierenga, R.K. (deposition date: 2002-07-03, release date: 2002-11-29, Last modification date: 2018-03-07)

• Primary citation: Kursula, P.,Ojala, J.,Lambeir, A.-M.,Wierenga, R.K.; The catalytic cycle of biosynthetic thiolase: A conformational journey of an acetyl group through four binding modes and two oxyanion holes; Biochemistry, 41:15543-15556, 2002; PubMed: 12501183; DOI: 10.1021/bi0266232

Experimental method

X-RAY DIFFRACTION (1.87 Å)