1M1O

Crystal structure of biosynthetic thiolase, C89A mutant, complexed with acetoacetyl-CoA

Summary for 1M1O

Entry DOI	10.2210/pdb1m1o/pdb
Related	1DLU 1DLV 1DM3 1M1T 1M3K 1M3Z 1M4S 1M4T 1QFL
Descriptor	Acetyl-CoA acetyltransferase, SULFATE ION, ACETOACETYL-COENZYME A, ... (4 entities in total)
Functional Keywords	thiolase fold, transferase
Biological source	Zoogloea ramigera
Cellular location	Cytoplasm: P07097
Total number of polymer chains	4
Total formula weight	164124.05
Authors	Kursula, P.,Ojala, J.,Lambeir, A.-M.,Wierenga, R.K. (deposition date: 2002-06-20, release date: 2002-11-29, Last modification date: 2024-02-14)
Primary citation	Kursula, P.,Ojala, J.,Lambeir, A.-M.,Wierenga, R.K. The catalytic cycle of biosynthetic thiolase: A conformational journey of an acetyl group through four binding modes and two oxyanion holes Biochemistry, 41:15543-15556, 2002 Cited by PubMed: 12501183 DOI: 10.1021/bi0266232 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.95 Å)

Structure validation