1M1O
Crystal structure of biosynthetic thiolase, C89A mutant, complexed with acetoacetyl-CoA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Acetyl-CoA acetyltransferase | polymer | 392 | 40509.1 | 4 | UniProt (P07097) Pfam (PF00108) Pfam (PF02803) | Zoogloea ramigera | Acetoacetyl-CoA thiolase; biosynthetic thiolase |
| 2 | E, F, H, I (A, B) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 3 | G, J (A, B) | ACETOACETYL-COENZYME A | non-polymer | 851.6 | 2 | Chemie (CAA) | |||
| 4 | K, L, M, N (A, B, C, D) | water | water | 18.0 | 1002 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 392 (UniProt: P07097)
| PDB | External Database | Details |
|---|---|---|
| Ala 10 | - | insertion |
| Ala 89 | Cys 88 | engineered mutation |
| Arg 129 | Ala 128 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 162036.6 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 2087.5 | |
| All* | Total formula weight | 164124.0 |
