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PDB: 195 件
8GL9
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BU of 8gl9 by Molmil
Co-crystal structure of caPCNA bound to AOH1160 derivative 1LE
分子名称: CHLORIDE ION, N~2~-(naphthalene-1-carbonyl)-N-(2-phenoxyphenyl)-L-alpha-glutamine, Proliferating cell nuclear antigen
著者Jossart, J, Kenjic, N, Malkas, L.H, Hickey, R.J, Perry, J.J.
登録日2023-03-21
公開日2023-07-26
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Small molecule targeting of transcription-replication conflict for selective chemotherapy.
Cell Chem Biol, 30, 2023
8GJ5
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BU of 8gj5 by Molmil
fungal pcna and peptidomimetic
分子名称: Proliferating cell nuclear antigen, THR-ASP-ILE-ARG-ASN-PHE-PHE-HIS-SER
著者Vandborg, B, Bruning, J.B.
登録日2023-03-14
公開日2024-01-24
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Towards a High-Affinity Peptidomimetic Targeting Proliferating Cell Nuclear Antigen from Aspergillus fumigatus.
J Fungi, 9, 2023
8GJF
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BU of 8gjf by Molmil
afupcna bound with peptide mimetic
分子名称: LYS-ARG-ARG-GLN-THR-SER-MET-THR-ASP-PHE-TYR-HIS-SER-LYS-ARG, Proliferating cell nuclear antigen
著者Vandborg, B, Bruning, J.B.
登録日2023-03-15
公開日2024-01-24
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Towards a High-Affinity Peptidomimetic Targeting Proliferating Cell Nuclear Antigen from Aspergillus fumigatus.
J Fungi, 9, 2023
3JA9
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BU of 3ja9 by Molmil
Structure of native human PCNA
分子名称: Proliferating cell nuclear antigen
著者Lau, W.C.Y, Li, Y, Zhang, Q, Huen, M.S.Y.
登録日2015-05-19
公開日2015-12-09
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (22 Å)
主引用文献Molecular architecture of the Ub-PCNA/Pol eta complex bound to DNA
Sci Rep, 5, 2015
6K2M
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BU of 6k2m by Molmil
Crystal structure of the complex of Proliferating Cell Nuclear Antigen from Leishmania donovani with arginine at 3.19 A resolution.
分子名称: ARGININE, Proliferating cell nuclear antigen
著者Viswanathan, V, Iqbal, N, Sharma, S, Singh, T.P.
登録日2019-05-15
公開日2019-05-29
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.19 Å)
主引用文献Crystal structure of the complex of Proliferating Cell Nuclear Antigen from Leishmania donovani with arginine at 3.19 A resolution.
To Be Published
8GCJ
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BU of 8gcj by Molmil
PCNA
分子名称: Proliferating cell nuclear antigen
著者Vandborg, B.C, Bruning, J.B.
登録日2023-03-01
公開日2024-05-29
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Crystal structure of apo pcna
To Be Published
5E0T
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BU of 5e0t by Molmil
Human PCNA mutant - S228I
分子名称: Proliferating cell nuclear antigen
著者Duffy, C.M, Hilbert, B.J, Kelch, B.A.
登録日2015-09-29
公開日2016-04-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.6653 Å)
主引用文献A Disease-Causing Variant in PCNA Disrupts a Promiscuous Protein Binding Site.
J.Mol.Biol., 428, 2016
5E0U
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BU of 5e0u by Molmil
Human PCNA variant (S228I) complexed with p21 at 1.9 Angstroms
分子名称: Cyclin-dependent kinase inhibitor 1, Proliferating cell nuclear antigen
著者Duffy, C.M, Hilbert, B.J, Kelch, B.A.
登録日2015-09-29
公開日2016-04-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献A Disease-Causing Variant in PCNA Disrupts a Promiscuous Protein Binding Site.
J.Mol.Biol., 428, 2016
2IJX
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BU of 2ijx by Molmil
Crystal structure of PCNA3 monomer from Sulfolobus solfataricus.
分子名称: 1,2-ETHANEDIOL, DNA polymerase sliding clamp A
著者Hlinkova, V, Ling, H.
登録日2006-10-01
公開日2007-10-16
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structures of monomeric, dimeric and trimeric PCNA: PCNA-ring assembly and opening.
Acta Crystallogr.,Sect.D, 64, 2008
6KNC
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BU of 6knc by Molmil
PolD-PCNA-DNA (form B)
分子名称: DNA polymerase D DP2 (DNA polymerase II large) subunit, DNA polymerase II small subunit, DNA polymerase sliding clamp 1, ...
著者Mayanagi, K, Oki, K, Miyazaki, N, Ishino, S, Yamagami, T, Iwasaki, K, Kohda, D, Morikawa, K, Shirai, T, Ishino, Y.
登録日2019-08-05
公開日2020-08-05
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (9.3 Å)
主引用文献Two conformations of DNA polymerase D-PCNA-DNA, an archaeal replisome complex, revealed by cryo-electron microscopy.
Bmc Biol., 18, 2020
6HVO
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BU of 6hvo by Molmil
Crystal structure of human PCNA in complex with three peptides of p12 subunit of human polymerase delta
分子名称: DNA polymerase delta subunit 4, Proliferating cell nuclear antigen, SULFATE ION
著者Gonzalez-Magana, A, Romano-Moreno, M, Rojas, A.L, Blanco, F.J, De Biasio, A.
登録日2018-10-11
公開日2019-01-23
最終更新日2019-03-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The p12 subunit of human polymerase delta uses an atypical PIP box for molecular recognition of proliferating cell nuclear antigen (PCNA).
J.Biol.Chem., 294, 2019
5DAI
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BU of 5dai by Molmil
Proliferating cell nuclear antigen homolog 1 bound to FEN-1 peptide
分子名称: C-terminus of FEN-1 protein, DNA polymerase sliding clamp 1, SULFATE ION
著者Ladner, J.E, Altieri, A.S, Kelman, Z.
登録日2015-08-20
公開日2016-05-11
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A small protein inhibits proliferating cell nuclear antigen by breaking the DNA clamp.
Nucleic Acids Res., 44, 2016
3GPN
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BU of 3gpn by Molmil
Structure of the non-trimeric form of the E113G PCNA mutant protein
分子名称: Proliferating cell nuclear antigen
著者Freudenthal, B.D, Gakhar, L, Ramaswamy, S, Washington, M.T.
登録日2009-03-23
公開日2009-06-16
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献A charged residue at the subunit interface of PCNA promotes trimer formation by destabilizing alternate subunit interactions.
Acta Crystallogr.,Sect.D, 65, 2009
5E0V
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BU of 5e0v by Molmil
Human PCNA variant (S228I) complexed with FEN1 at 2.1 Angstroms
分子名称: Flap endonuclease 1, Proliferating cell nuclear antigen
著者Duffy, C.M, Hilbert, B.J, Kelch, B.A.
登録日2015-09-29
公開日2016-04-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.074 Å)
主引用文献A Disease-Causing Variant in PCNA Disrupts a Promiscuous Protein Binding Site.
J.Mol.Biol., 428, 2016
3K4X
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BU of 3k4x by Molmil
Eukaryotic Sliding Clamp PCNA Bound to DNA
分子名称: DNA (5'-D(*CP*CP*CP*AP*TP*CP*GP*TP*AP*T)-3'), DNA (5'-D(*TP*TP*TP*TP*AP*TP*AP*CP*GP*AP*TP*GP*GP*G)-3'), Proliferating cell nuclear antigen
著者McNally, R, Kuriyan, J.
登録日2009-10-06
公開日2010-02-16
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.98 Å)
主引用文献Analysis of the role of PCNA-DNA contacts during clamp loading.
Bmc Struct.Biol., 10, 2010
5CFK
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BU of 5cfk by Molmil
Crystal structure of Proliferating Cell Nuclear Antigen from Leishmania donovani at 3.2 A resolution
分子名称: Proliferating cell nuclear antigen,Proliferating cell nuclear antigen
著者Shukla, P.K, Yadav, S.P, Sharma, P, Kaur, P, Sharma, S, Singh, T.P.
登録日2015-07-08
公開日2015-10-07
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal structure of Proliferating Cell Nuclear Antigen from Leishmania donovani at 3.2 A resolution
To Be Published
6K3A
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BU of 6k3a by Molmil
Crystal structure of human PCNA in complex with DNMT1 PIP box motif.
分子名称: Peptide from DNA (cytosine-5)-methyltransferase 1, Proliferating cell nuclear antigen
著者Jimenji, T, Kori, S, Arita, K.
登録日2019-05-17
公開日2019-06-26
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of PCNA in complex with DNMT1 PIP box reveals the basis for the molecular mechanism of the interaction.
Biochem.Biophys.Res.Commun., 516, 2019
2HII
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BU of 2hii by Molmil
heterotrimeric PCNA sliding clamp
分子名称: PCNA1 (SSO0397), PCNA2 (SSO1047), PCNA3 (SSO0405)
著者Pascal, J.M, Tsodikov, O.V, Ellenberger, T.
登録日2006-06-29
公開日2006-11-07
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献A Flexible Interface between DNA Ligase and PCNA Supports Conformational Switching and Efficient Ligation of DNA.
Mol.Cell, 24, 2006
2HIK
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BU of 2hik by Molmil
heterotrimeric PCNA sliding clamp
分子名称: PCNA1 (SSO0397), PCNA2 (SSO1047), PCNA3 (SSO0405)
著者Pascal, J.M, Tsodikov, O.V, Ellenberger, T.
登録日2006-06-29
公開日2006-11-07
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献A Flexible Interface between DNA Ligase and PCNA Supports Conformational Switching and Efficient Ligation of DNA.
Mol.Cell, 24, 2006
6KNB
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BU of 6knb by Molmil
PolD-PCNA-DNA (form A)
分子名称: DNA polymerase D DP2 (DNA polymerase II large) subunit, DNA polymerase II small subunit, DNA polymerase sliding clamp 1, ...
著者Mayanagi, K, Oki, K, Miyazaki, N, Ishino, S, Yamagami, T, Iwasaki, K, Kohda, D, Morikawa, K, Shirai, T, Ishino, Y.
登録日2019-08-05
公開日2020-08-05
最終更新日2021-02-17
実験手法ELECTRON MICROSCOPY (6.9 Å)
主引用文献Two conformations of DNA polymerase D-PCNA-DNA, an archaeal replisome complex, revealed by cryo-electron microscopy.
Bmc Biol., 18, 2020
6AIG
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BU of 6aig by Molmil
Crystal structure of PCNA1 from Aeropyrum pernix
分子名称: DNA polymerase sliding clamp 1
著者Yamauchi, T, Kikuchi, M, Tsunoda, M.
登録日2018-08-23
公開日2018-09-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of PCNA1 from Aeropyrum pernix
To Be Published
6CBI
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BU of 6cbi by Molmil
PCNA in complex with inhibitor
分子名称: GLY-ARG-LYS-ARG-ARG-GLN-DAB-SER-MET-THR-GLU-PHE-TYR-HIS, Proliferating cell nuclear antigen, SULFATE ION
著者Bruning, J.B, Wegener, K.L.
登録日2018-02-03
公開日2018-07-04
最終更新日2020-01-29
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Rational Design of a 310-Helical PIP-Box Mimetic Targeting PCNA, the Human Sliding Clamp.
Chemistry, 24, 2018
6CX3
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BU of 6cx3 by Molmil
S179T Mutant of Yeast PCNA
分子名称: Proliferating cell nuclear antigen
著者Powers, K.T.
登録日2018-04-02
公開日2018-04-11
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.101 Å)
主引用文献Identification of New Mutations at the PCNA Subunit Interface that Block Translesion Synthesis.
PLoS ONE, 11, 2016
6CX2
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S177G Mutant of Yeast PCNA
分子名称: Proliferating cell nuclear antigen
著者Powers, K.T.
登録日2018-04-02
公開日2018-04-11
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.101 Å)
主引用文献Identification of New Mutations at the PCNA Subunit Interface that Block Translesion Synthesis.
PLoS ONE, 11, 2016
6CX4
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V180A Mutant of Yeast PCNA
分子名称: Proliferating cell nuclear antigen
著者Powers, K.T.
登録日2018-04-02
公開日2018-04-11
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.081 Å)
主引用文献Identification of New Mutations at the PCNA Subunit Interface that Block Translesion Synthesis.
PLoS ONE, 11, 2016

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