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PDB: 55 件
4MM2
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BU of 4mm2 by Molmil
Crystal structure of yeast primase catalytic subunit
分子名称: CADMIUM ION, CITRIC ACID, DNA primase small subunit
著者Park, K.R, An, J.Y, Lee, Y, Youn, H.S, Lee, J.G, Kang, J.Y, Kim, T.G, Lim, J.J, Eom, S.H, Wang, J.
登録日2013-09-07
公開日2014-09-10
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structure of yeast primase catalytic subunit
To be Published
4MHQ
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BU of 4mhq by Molmil
Crystal structure of human primase catalytic subunit
分子名称: CITRIC ACID, DNA primase small subunit, ZINC ION
著者Park, K.R, An, J.Y, Lee, Y, Youn, H.S, Lee, J.G, Kang, J.Y, Kim, T.G, Lim, J.J, Eom, S.H, Wang, J.
登録日2013-08-30
公開日2014-09-03
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of human primase catalytic subunit
To be Published
1V33
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BU of 1v33 by Molmil
Crystal structure of DNA primase from Pyrococcus horikoshii
分子名称: DNA primase small subunit, PHOSPHATE ION, ZINC ION
著者Ito, N, Nureki, O, Shirouzu, M, Yokoyama, S, Hanaoka, F, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2003-10-25
公開日2004-03-23
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of the Pyrococcus horikoshii DNA primase-UTP complex: implications for the mechanism of primer synthesis.
Genes Cells, 8, 2003
5L2X
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BU of 5l2x by Molmil
Crystal structure of human PrimPol ternary complex
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(P*GP*GP*TP*AP*GP*CP*(DDG))-3'), ...
著者Rechkoblit, O, Gupta, Y.K, Malik, R, Rajashankar, K.R, Johnson, R.E, Prakash, L, Prakash, S, Aggarwal, A.K.
登録日2016-08-02
公開日2016-11-23
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure and mechanism of human PrimPol, a DNA polymerase with primase activity.
Sci Adv, 2, 2016
1V34
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BU of 1v34 by Molmil
Crystal structure of Pyrococcus horikoshii DNA primase-UTP complex
分子名称: DNA primase small subunit, URIDINE 5'-TRIPHOSPHATE, ZINC ION
著者Ito, N, Nureki, O, Shirouzu, M, Yokoyama, S, Hanaoka, F, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2003-10-25
公開日2004-03-23
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of the Pyrococcus horikoshii DNA primase-UTP complex: implications for the mechanism of primer synthesis.
Genes Cells, 8, 2003
1G71
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BU of 1g71 by Molmil
CRYSTAL STRUCTURE OF PYROCOCCUS FURIOSUS DNA PRIMASE
分子名称: CHLORIDE ION, DNA PRIMASE, SULFATE ION, ...
著者Augustin, M.A, Huber, R, Kaiser, J.T.
登録日2000-11-08
公開日2001-01-10
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of a DNA-dependent RNA polymerase (DNA primase).
Nat.Struct.Biol., 8, 2001
4BPU
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BU of 4bpu by Molmil
Crystal structure of human primase in heterodimeric form, comprising PriS and truncated PriL lacking the C-terminal Fe-S domain.
分子名称: DNA PRIMASE LARGE SUBUNIT, DNA PRIMASE SMALL SUBUNIT, GLYCEROL, ...
著者Kilkenny, M.L, Perera, R.L, Pellegrini, L.
登録日2013-05-28
公開日2013-09-25
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structures of Human Primase Reveal Design of Nucleotide Elongation Site and Mode of Pol Alpha Tethering
Proc.Natl.Acad.Sci.USA, 110, 2013
4BPX
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BU of 4bpx by Molmil
Crystal structure of human primase in complex with the primase- binding motif of DNA polymerase alpha
分子名称: DNA POLYMERASE ALPHA CATALYTIC SUBUNIT, DNA PRIMASE LARGE SUBUNIT, DNA PRIMASE SMALL SUBUNIT, ...
著者Kilkenny, M.L, Perera, R.L, Pellegrini, L.
登録日2013-05-28
公開日2013-09-25
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structures of Human Primase Reveal Design of Nucleotide Elongation Site and Mode of Pol Alpha Tethering
Proc.Natl.Acad.Sci.USA, 110, 2013
4BPW
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BU of 4bpw by Molmil
Crystal structure of human primase bound to UTP
分子名称: DNA PRIMASE LARGE SUBUNIT, DNA PRIMASE SMALL SUBUNIT, MAGNESIUM ION, ...
著者Kilkenny, M.L, Perera, R.L, Pellegrini, L.
登録日2013-05-28
公開日2013-09-25
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.003 Å)
主引用文献Structures of Human Primase Reveal Design of Nucleotide Elongation Site and Mode of Pol Alpha Tethering
Proc.Natl.Acad.Sci.USA, 110, 2013
4LIK
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BU of 4lik by Molmil
Crystal structure of the catalytic subunit of human primase
分子名称: CITRIC ACID, DNA primase small subunit, ZINC ION
著者Vaithiyalingam, S, Eichman, B.F, Chazin, W.J.
登録日2013-07-02
公開日2013-12-11
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Insights into Eukaryotic Primer Synthesis from Structures of the p48 Subunit of Human DNA Primase.
J.Mol.Biol., 426, 2014
4LIM
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BU of 4lim by Molmil
Crystal structure of the catalytic subunit of yeast primase
分子名称: DNA primase small subunit, ZINC ION
著者Vaithiyalingam, S, Chazin, W.J, Berger, J.M, Corn, J, Stephenson, S.
登録日2013-07-02
公開日2013-12-18
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Insights into Eukaryotic Primer Synthesis from Structures of the p48 Subunit of Human DNA Primase.
J.Mol.Biol., 426, 2014
4LIL
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BU of 4lil by Molmil
Crystal structure of the catalytic subunit of human primase bound to UTP and Mn
分子名称: DNA primase small subunit, MANGANESE (II) ION, URIDINE 5'-TRIPHOSPHATE, ...
著者Vaithiyalingam, S, Eichman, B.F, Chazin, W.J.
登録日2013-07-02
公開日2013-12-11
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Insights into Eukaryotic Primer Synthesis from Structures of the p48 Subunit of Human DNA Primase.
J.Mol.Biol., 426, 2014
7JKL
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BU of 7jkl by Molmil
Human PrimPol misinserting dATP opposite the 8-oxoguanine lesion (3'-end base of the primer strand is 2',3'-dideoxy-terminated).
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*GP*GP*TP*GP*TP*GP*GP*TP*AP*GP*CP*(DDG))-3'), ...
著者Rechkoblit, O, Aggarwal, A.K.
登録日2020-07-28
公開日2021-06-30
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.384 Å)
主引用文献Structural basis of DNA synthesis opposite 8-oxoguanine by human PrimPol primase-polymerase.
Nat Commun, 12, 2021
7JLG
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BU of 7jlg by Molmil
Human PrimPol extending from the erroneous primer base A opposite the 8-oxoguanine lesion
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ...
著者Rechkoblit, O, Aggarwal, A.K.
登録日2020-07-29
公開日2021-06-30
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Structural basis of DNA synthesis opposite 8-oxoguanine by human PrimPol primase-polymerase.
Nat Commun, 12, 2021
7JKP
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BU of 7jkp by Molmil
Human PrimPol misinserting dATP opposite the 8-oxoguanine lesion
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*GP*GP*TP*GP*TP*GP*GP*TP*AP*GP*CP*G)-3'), ...
著者Rechkoblit, O, Aggarwal, A.K.
登録日2020-07-28
公開日2021-06-30
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.592 Å)
主引用文献Structural basis of DNA synthesis opposite 8-oxoguanine by human PrimPol primase-polymerase.
Nat Commun, 12, 2021
7JL8
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BU of 7jl8 by Molmil
Human PrimPol extending from the correct primer base C opposite the 8-oxoguanine lesion
分子名称: 1,2-ETHANEDIOL, 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, ...
著者Rechkoblit, O, Aggarwal, A.K.
登録日2020-07-29
公開日2021-06-30
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis of DNA synthesis opposite 8-oxoguanine by human PrimPol primase-polymerase.
Nat Commun, 12, 2021
7JK1
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BU of 7jk1 by Molmil
Human PrimPol inserting correct dCTP opposite the 8-oxoguanine lesion
分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ...
著者Rechkoblit, O, Aggarwal, A.K.
登録日2020-07-27
公開日2021-06-30
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Structural basis of DNA synthesis opposite 8-oxoguanine by human PrimPol primase-polymerase.
Nat Commun, 12, 2021
6R4U
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BU of 6r4u by Molmil
Crystal structure of the Pri1 subunit of human primase bound to fludarabine triphosphate
分子名称: 1,2-ETHANEDIOL, 2-fluoro-9-{5-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-beta-D-arabinofuranosyl}-9H-purin-6-a mine, DNA primase small subunit, ...
著者Kilkenny, M.L, Pellegrini, L.
登録日2019-03-24
公開日2019-09-11
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Basis for Inhibition of Human Primase by Arabinofuranosyl Nucleoside Analogues Fludarabine and Vidarabine.
Acs Chem.Biol., 14, 2019
6RB4
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BU of 6rb4 by Molmil
Crystal structure of the Pri1 subunit of human primase
分子名称: 1,2-ETHANEDIOL, DNA primase small subunit, ZINC ION
著者Kilkenny, M.L, Pellegrini, L.
登録日2019-04-09
公開日2019-09-11
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural Basis for Inhibition of Human Primase by Arabinofuranosyl Nucleoside Analogues Fludarabine and Vidarabine.
Acs Chem.Biol., 14, 2019
6R5D
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BU of 6r5d by Molmil
Crystal structure of the Pri1 subunit of human primase bound to dATP
分子名称: 1,2-ETHANEDIOL, 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA primase small subunit, ...
著者Kilkenny, M.L, Pellegrini, L.
登録日2019-03-24
公開日2019-09-11
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural Basis for Inhibition of Human Primase by Arabinofuranosyl Nucleoside Analogues Fludarabine and Vidarabine.
Acs Chem.Biol., 14, 2019
6R4S
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BU of 6r4s by Molmil
Crystal structure of the Pri1 subunit of human primase bound to ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, DNA primase small subunit, MANGANESE (II) ION, ...
著者Kilkenny, M.L, Pellegrini, L.
登録日2019-03-24
公開日2019-09-11
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structural Basis for Inhibition of Human Primase by Arabinofuranosyl Nucleoside Analogues Fludarabine and Vidarabine.
Acs Chem.Biol., 14, 2019
6R4T
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BU of 6r4t by Molmil
Crystal structure of the Pri1 subunit of human primase bound to vidarabine triphosphate
分子名称: 1,2-ETHANEDIOL, 9-{5-O-[(S)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-beta-D-arabinofuranosyl}-9H-purin-6-amine, DNA primase small subunit, ...
著者Kilkenny, M.L, Pellegrini, L.
登録日2019-03-24
公開日2019-09-11
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural Basis for Inhibition of Human Primase by Arabinofuranosyl Nucleoside Analogues Fludarabine and Vidarabine.
Acs Chem.Biol., 14, 2019
6R5E
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BU of 6r5e by Molmil
Crystal structure of the Pri1 subunit of human primase bound to 2F-ATP
分子名称: 1,2-ETHANEDIOL, 2-fluoro-ATP, DNA primase small subunit, ...
著者Kilkenny, M.L, Pellegrini, L.
登録日2019-03-24
公開日2019-09-11
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural Basis for Inhibition of Human Primase by Arabinofuranosyl Nucleoside Analogues Fludarabine and Vidarabine.
Acs Chem.Biol., 14, 2019
4RR2
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BU of 4rr2 by Molmil
Crystal structure of human primase
分子名称: DNA primase large subunit, DNA primase small subunit, IRON/SULFUR CLUSTER, ...
著者Baranovskiy, A.G, Gu, J, Suwa, Y, Babayeva, N.D, Tahirov, T.H.
登録日2014-11-05
公開日2015-01-21
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Crystal structure of the human primase.
J.Biol.Chem., 290, 2015
1ZT2
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BU of 1zt2 by Molmil
Heterodimeric structure of the core primase.
分子名称: DNA primase large subunit, DNA primase small subunit, SULFATE ION, ...
著者Lao-Sirieix, S.H, Nookala, R.K, Roversi, P, Bell, S.D, Pellegrini, L.
登録日2005-05-26
公開日2005-11-08
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.33 Å)
主引用文献Structure of the heterodimeric core primase.
Nat.Struct.Mol.Biol., 12, 2005

 

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