5L2X

Crystal structure of human PrimPol ternary complex

Summary for 5L2X

• Entry DOI: 10.2210/pdb5l2x/pdb
• Descriptor: DNA-directed primase/polymerase protein, DNA (5'-D(P*TP*CP*GP*CP*(5IU)P*AP*CP*C)-3'), DNA (5'-D(P*GP*GP*TP*AP*GP*CP*(DDG))-3'), ... (6 entities in total)
• Functional Keywords: protein-dna complex, transferase-dna complex, transferase/dna
• Biological source: Homo sapiens (Human); More
• Cellular location: Nucleus: Q96LW4
• Total number of polymer chains: 6
• Total formula weight: 101354.75

Authors

Rechkoblit, O.,Gupta, Y.K.,Malik, R.,Rajashankar, K.R.,Johnson, R.E.,Prakash, L.,Prakash, S.,Aggarwal, A.K. (deposition date: 2016-08-02, release date: 2016-11-23, Last modification date: 2024-03-06)

• Primary citation: Rechkoblit, O.,Gupta, Y.K.,Malik, R.,Rajashankar, K.R.,Johnson, R.E.,Prakash, L.,Prakash, S.,Aggarwal, A.K.; Structure and mechanism of human PrimPol, a DNA polymerase with primase activity.; Sci Adv, 2:e1601317-e1601317, 2016; PubMed: 27819052; DOI: 10.1126/sciadv.1601317

Experimental method

X-RAY DIFFRACTION (2.2 Å)