5L2X
Crystal structure of human PrimPol ternary complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, B) | DNA-directed primase/polymerase protein | polymer | 353 | 40909.3 | 2 | UniProt (Q96LW4) Pfam (PF01896) | Homo sapiens (Human) | hPrimpol1,Coiled-coil domain-containing protein 111 |
| 2 | B, E (C, G) | DNA (5'-D(P*TP*CP*GP*CP*(5IU)P*AP*CP*C)-3') | polymer | 17 | 5149.1 | 2 | Homo sapiens | ||
| 3 | C, F (D, H) | DNA (5'-D(P*GP*GP*TP*AP*GP*CP*(DDG))-3') | polymer | 13 | 4087.7 | 2 | Homo sapiens | ||
| 4 | G, I (A, B) | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE | non-polymer | 491.2 | 2 | Chemie (DTP) | |||
| 5 | H, J (A, B) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 6 | K, L, M, N, O (A, C, B, G, H) | water | water | 18.0 | 98 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 353 (UniProt: Q96LW4)
| PDB | External Database | Details |
|---|---|---|
| Arg 168 | Gln 168 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 100292.2 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1062.5 | |
| All* | Total formula weight | 101354.7 |
