6ZTN
| E. coli 70S-RNAP expressome complex in NusG-coupled state (42 nt intervening mRNA) | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Webster, M.W, Takacs, M, Weixlbaumer, A. | 登録日 | 2020-07-20 | 公開日 | 2020-09-16 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structural basis of transcription-translation coupling and collision in bacteria. Science, 369, 2020
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6ZN5
| SARS-CoV-2 Nsp1 bound to a pre-40S-like ribosome complex - state 2 | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | 著者 | Thoms, M, Buschauer, R, Ameismeier, M, Denk, T, Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. | 登録日 | 2020-07-06 | 公開日 | 2020-07-29 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2. Science, 369, 2020
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6ZP4
| SARS-CoV-2 Nsp1 bound to a human 43S preinitiation ribosome complex - state 2 | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | 著者 | Thoms, M, Buschauer, R, Ameismeier, M, Denk, T, Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. | 登録日 | 2020-07-08 | 公開日 | 2020-07-29 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2. Science, 369, 2020
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6ZTL
| E. coli 70S-RNAP expressome complex in collided state bound to NusG | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Webster, M.W, Takacs, M, Weixlbaumer, A. | 登録日 | 2020-07-20 | 公開日 | 2020-09-16 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structural basis of transcription-translation coupling and collision in bacteria. Science, 369, 2020
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6ZVJ
| Structure of a human ABCE1-bound 43S pre-initiation complex - State II | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | 著者 | Kratzat, H, Mackens-Kiani, T, Ameismeier, A, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. | 登録日 | 2020-07-24 | 公開日 | 2020-10-07 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | A structural inventory of native ribosomal ABCE1-43S pre-initiation complexes. Embo J., 40, 2021
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6ZVK
| The Halastavi arva virus (HalV) intergenic region IRES promotes translation by the simplest possible initiation mechanism | 分子名称: | 18S RIBOSOMAL RNA, 28S RIBOSOMAL RNA, 40S RIBOSOMAL PROTEIN ES17, ... | 著者 | Abaeva, I.S, Vicens, Q, Bochler, A, Soufari, H, Simonetti, A, Pestova, T, Hashem, Y, Hellen, C.U.T. | 登録日 | 2020-07-24 | 公開日 | 2020-12-23 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.49 Å) | 主引用文献 | The Halastavi arva Virus Intergenic Region IRES Promotes Translation by the Simplest Possible Initiation Mechanism. Cell Rep, 33, 2020
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6ZMW
| Structure of a human 48S translational initiation complex | 分子名称: | 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | 著者 | Brito Querido, J, Sokabe, M, Kraatz, S, Gordiyenko, Y, Skehel, M, Fraser, C, Ramakrishnan, V. | 登録日 | 2020-07-04 | 公開日 | 2020-09-23 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structure of a human 48Stranslational initiation complex. Science, 369, 2020
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6ZQD
| Cryo-EM structure of the 90S pre-ribosome from Saccharomyces cerevisiae, state Post-A1 | 分子名称: | 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S1-A, ... | 著者 | Cheng, J, Lau, B, Venuta, G.L, Berninghausen, O, Hurt, E, Beckmann, R. | 登録日 | 2020-07-09 | 公開日 | 2020-09-23 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | 90 S pre-ribosome transformation into the primordial 40 S subunit. Science, 369, 2020
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7AZO
| 70S thermus thermophilus ribosome with bound antibiotic lead SEQ-977 | 分子名称: | (2R,3S,4R,5R,7S,9S,10S,11R,12S,13R)-12-(((2R,4R,5S,6S)-4,5-dihydroxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-2-((S)-1-(((2R,3R,4R,5R,6R)-5-hydroxy-3,4-dimethoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)propan-2-yl)-10-(((2S,3R,4R,6R)-3-hydroxy-4-(methoxyamino)-6-methyltetrahydro-2H-pyran-2-yl)oxy)-3,5,7,9,11,13-hexamethyl-7-(((2-((2-nitrophenyl)sulfonamido)ethyl)carbamoyl)oxy)-6,14-dioxooxacyclotetradecan-4-yl 3-methylbutanoate, 16S rRNA, 23S rRNA, ... | 著者 | Jenner, L.B, Yusupov, M, Yusupova, G. | 登録日 | 2020-11-17 | 公開日 | 2022-06-01 | 最終更新日 | 2024-04-24 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Discovery of natural-product-derived sequanamycins as potent oral anti-tuberculosis agents. Cell, 186, 2023
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7AZS
| 70S thermus thermophilus ribosome with bound antibiotic lead SEQ-569 | 分子名称: | (2R,3S,4R,5R,7S,9S,10S,11R,12S,13R)-12-(((2R,4R,5S,6S)-4,5-dihydroxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-2-((S)-1-(((2R,3R,4R,5R,6R)-5-hydroxy-3,4-dimethoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)propan-2-yl)-10-(((2S,3R,6R,E)-3-hydroxy-4-(methoxyimino)-6-methyltetrahydro-2H-pyran-2-yl)oxy)-3,5,7,9,11,13-hexamethyl-7-(((2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl)carbamoyl)oxy)-6,14-dioxooxacyclotetradecan-4-yl 3-methylbutanoate, 16S rRNA, 23S rRNA, ... | 著者 | Jenner, L.B, Yusupov, M, Yusupova, G, Rak, A. | 登録日 | 2020-11-17 | 公開日 | 2022-06-08 | 最終更新日 | 2024-04-24 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Discovery of natural-product-derived sequanamycins as potent oral anti-tuberculosis agents. Cell, 186, 2023
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6ZTM
| E. coli 70S-RNAP expressome complex in collided state without NusG | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Webster, M.W, Takacs, M, Weixlbaumer, A. | 登録日 | 2020-07-20 | 公開日 | 2020-09-16 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural basis of transcription-translation coupling and collision in bacteria. Science, 369, 2020
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7A09
| Structure of a human ABCE1-bound 43S pre-initiation complex - State III | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | 著者 | Kratzat, H, Mackens-Kiani, T, Ameismeier, A, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. | 登録日 | 2020-08-07 | 公開日 | 2020-10-14 | 最終更新日 | 2021-01-13 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | A structural inventory of native ribosomal ABCE1-43S pre-initiation complexes. Embo J., 40, 2021
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6ZVH
| EDF1-ribosome complex | 分子名称: | 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | 著者 | Best, K.M, Denk, T, Cheng, J, Thoms, M, Berninghausen, O, Beckmann, R. | 登録日 | 2020-07-24 | 公開日 | 2020-08-19 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | EDF1 coordinates cellular responses to ribosome collisions. Elife, 9, 2020
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6ZXE
| Cryo-EM structure of a late human pre-40S ribosomal subunit - State F2 | 分子名称: | 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S12, ... | 著者 | Ameismeier, M, Zemp, I, van den Heuvel, J, Thoms, M, Berninghausen, O, Kutay, U, Beckmann, R. | 登録日 | 2020-07-29 | 公開日 | 2020-12-02 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural basis for the final steps of human 40S ribosome maturation. Nature, 587, 2020
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7A1G
| Structure of a crosslinked yeast ABCE1-bound 43S pre-initiation complex | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ... | 著者 | Mackens-Kiani, T, Kratzat, H, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. | 登録日 | 2020-08-13 | 公開日 | 2020-10-14 | 最終更新日 | 2023-11-29 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | A structural inventory of native ribosomal ABCE1-43S pre-initiation complexes. Embo J., 40, 2021
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6ZXG
| Cryo-EM structure of a late human pre-40S ribosomal subunit - State H1 | 分子名称: | 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S12, ... | 著者 | Ameismeier, M, Zemp, I, van den Heuvel, J, Thoms, M, Berninghausen, O, Kutay, U, Beckmann, R. | 登録日 | 2020-07-29 | 公開日 | 2020-12-02 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Structural basis for the final steps of human 40S ribosome maturation. Nature, 587, 2020
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6ZLW
| SARS-CoV-2 Nsp1 bound to the human 40S ribosomal subunit | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | 著者 | Thoms, M, Buschauer, R, Ameismeier, M, Denk, T, Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. | 登録日 | 2020-07-01 | 公開日 | 2020-07-29 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2. Science, 369, 2020
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6ZOJ
| SARS-CoV-2-Nsp1-40S complex, composite map | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | 著者 | Schubert, K, Karousis, E.D, Jomaa, A, Scaiola, A, Echeverria, B, Gurzeler, L.-A, Leibundgut, M.L, Thiel, V, Muehlemann, O, Ban, N. | 登録日 | 2020-07-07 | 公開日 | 2020-07-22 | 最終更新日 | 2021-02-10 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | SARS-CoV-2 Nsp1 binds the ribosomal mRNA channel to inhibit translation. Nat.Struct.Mol.Biol., 27, 2020
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7BL5
| pre-50S-ObgE particle | 分子名称: | 23S ribosomal RNA, 50S ribosomal protein L10, 50S ribosomal protein L11, ... | 著者 | Hilal, T, Nikolay, R, Spahn, C.M.T, Schmidt, S. | 登録日 | 2021-01-18 | 公開日 | 2021-05-12 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Snapshots of native pre-50S ribosomes reveal a biogenesis factor network and evolutionary specialization. Mol.Cell, 81, 2021
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7BOI
| Bacterial 30S ribosomal subunit assembly complex state F (multibody refinement for body domain of 30S ribosome) | 分子名称: | 16S rRNA, 30S ribosomal protein S11, 30S ribosomal protein S12, ... | 著者 | Schedlbauer, A, Iturrioz, I, Ochoa-Lizarralde, B, Diercks, T, Kaminishi, T, Capuni, R, Astigarraga, E, Gil-Carton, D, Fucini, P, Connell, S. | 登録日 | 2021-01-25 | 公開日 | 2021-07-07 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.98 Å) | 主引用文献 | A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit. Sci Adv, 7, 2021
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7BOF
| Bacterial 30S ribosomal subunit assembly complex state I (body domain) | 分子名称: | 16S rRNA, 30S ribosomal protein S11, 30S ribosomal protein S12, ... | 著者 | Schedlbauer, A, Iturrioz, I, Ochoa-Lizarralde, B, Diercks, T, Lopez-Alonso, J, Kaminishi, T, Capuni, R, Astigarraga, E, Gil-Carton, D, Fucini, P, Connell, S. | 登録日 | 2021-01-25 | 公開日 | 2021-07-07 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.92 Å) | 主引用文献 | A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit. Sci Adv, 7, 2021
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7B5K
| E. coli 70S containing suppressor tRNA in the A-site stabilized by a Negamycin analogue and P-site tRNA-nascent chain. | 分子名称: | 16S rRNA, 2-[[[(3~{R},5~{R})-3-azanyl-6-(3-azanylpropylamino)-5-oxidanyl-hexanoyl]amino]-methyl-amino]ethanoic acid, 23S rRNA, ... | 著者 | Albers, S, Beckert, B, Matthies, M, Schuster, R, Riedner, M, Seuring, C, Sanyal, S, Torda, A, Wilson, N.D, Ignatova, Z. | 登録日 | 2020-12-03 | 公開日 | 2021-05-26 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Harnessing evolutionarily flexibility in tRNAs to maximize nonsense suppression activities Nat Commun, 2021
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7AFI
| Bacterial 30S ribosomal subunit assembly complex state C (body domain) | 分子名称: | 16SrRNA, 30S ribosomal protein S11, 30S ribosomal protein S12, ... | 著者 | Schedlbauer, A, Iturrioz, I, Ochoa-Lizarralde, B, Diercks, T, Kaminishi, T, Capuni, R, Astigarraga, E, Gil-Carton, D, Fucini, P, Connell, S. | 登録日 | 2020-09-19 | 公開日 | 2021-07-07 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.53 Å) | 主引用文献 | A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit. Sci Adv, 7, 2021
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7AFL
| Bacterial 30S ribosomal subunit assembly complex state D (multibody refinement for body domain of 30S ribosome) | 分子名称: | 16SrRNA, 30S ribosomal protein S11, 30S ribosomal protein S12, ... | 著者 | Schedlbauer, A, Iturrioz, I, Ochoa-Lizarralde, B, Diercks, T, Kaminishi, T, Capuni, R, Astigarraga, E, Gil-Carton, D, Fucini, P, Connell, S. | 登録日 | 2020-09-19 | 公開日 | 2021-07-07 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit. Sci Adv, 7, 2021
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7AFO
| Bacterial 30S ribosomal subunit assembly complex state B (body domain) | 分子名称: | 16SrRNA (body domain of the 30S ribosome), 30S ribosomal protein S11, 30S ribosomal protein S12, ... | 著者 | Schedlbauer, A, Iturrioz, I, Ochoa-Lizarralde, B, Diercks, T, Kaminishi, T, Capuni, R, Astigarraga, E, Gil-Carton, D, Fucini, P, Connell, S. | 登録日 | 2020-09-19 | 公開日 | 2021-07-07 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.93 Å) | 主引用文献 | A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit. Sci Adv, 7, 2021
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