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PDB: 1477 件

5V93
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Cryo-EM structure of the 70S ribosome from Mycobacterium tuberculosis bound with Capreomycin
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Yang, K, Chang, J.-Y, Cui, Z, Li, X, Meng, R, Duan, L, Thongchol, J, Jakana, J, Huwe, C, Sacchettini, J, Zhang, J.
登録日2017-03-22
公開日2017-09-20
最終更新日2020-08-12
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structural insights into species-specific features of the ribosome from the human pathogen Mycobacterium tuberculosis.
Nucleic Acids Res., 45, 2017
5TCU
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Methicillin sensitive Staphylococcus aureus 70S ribosome
分子名称: 16S RRNA, 23S RRNA, 30S ribosomal protein S10, ...
著者Eyal, Z, Ahmed, T, Belousoff, N, Mishra, S, Matzov, D, Bashan, A, Zimmerman, E, Lithgow, T, Bhushan, S, Yonath, A.
登録日2016-09-15
公開日2017-05-24
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural Basis for Linezolid Binding Site Rearrangement in the Staphylococcus aureus Ribosome.
MBio, 8, 2017
5VP2
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Crystal structure of the Thermus thermophilus 70S ribosome in complex with madumycin II and bound to mRNA and A-, P- and E-site tRNAs at 2.8A resolution
分子名称: 16S ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
著者Osterman, I.A, Khabibullina, N.F, Komarova, E.S, Kasatsky, P, Kartsev, V.G, Bogdanov, A.A, Dontsova, O.A, Konevega, A.L, Sergiev, P.V, Polikanov, Y.S.
登録日2017-05-04
公開日2017-06-28
最終更新日2024-04-24
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Madumycin II inhibits peptide bond formation by forcing the peptidyl transferase center into an inactive state.
Nucleic Acids Res., 45, 2017
5U4J
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Structural Basis of Co-translational Quality Control by ArfA and RF2 Bound to Ribosome
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S12, ...
著者Zeng, F, Chen, Y, Remis, J, Shekhar, M, Phillips, J.C, Tajkhorshid, E, Jin, H.
登録日2016-12-04
公開日2017-01-11
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structural basis of co-translational quality control by ArfA and RF2 bound to ribosome.
Nature, 541, 2017
5UYK
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70S ribosome bound with cognate ternary complex not base-paired to A site codon (Structure I)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Loveland, A.B, Demo, G, Grigorieff, N, Korostelev, A.A.
登録日2017-02-24
公開日2017-06-07
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Ensemble cryo-EM elucidates the mechanism of translation fidelity
Nature, 546, 2017
5TZS
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Architecture of the yeast small subunit processome
分子名称: 13 kDa ribonucleoprotein-associated protein, 18S ribosomal RNA, 3' domain-associated, ...
著者Chaker-Margot, M, Barandun, J, Hunziker, M, Klinge, S.
登録日2016-11-22
公開日2016-12-21
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (5.1 Å)
主引用文献Architecture of the yeast small subunit processome.
Science, 355, 2017
5UYN
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70S ribosome bound with near-cognate ternary complex not base-paired to A site codon (Structure I-nc)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Loveland, A.B, Demo, G, Grigorieff, N, Korostelev, A.A.
登録日2017-02-24
公開日2017-06-07
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Ensemble cryo-EM elucidates the mechanism of translation fidelity
Nature, 546, 2017
5W4K
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Crystal structure of the Thermus thermophilus 70S ribosome in complex with Klebsazolicin and bound to mRNA and A-, P- and E-site tRNAs at 2.7A resolution
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
著者Metelev, M, Osterman, I.A, Ghilarov, D, Khabibullina, N.F, Yakimov, A, Shabalin, K, Utkina, I, Travin, D.Y, Komarova, E.S, Serebryakova, M, Artamonova, T, Khodorkovskii, M, Konevega, A.L, Sergiev, P.V, Severinov, K, Polikanov, Y.S.
登録日2017-06-12
公開日2017-08-30
最終更新日2019-12-04
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Klebsazolicin inhibits 70S ribosome by obstructing the peptide exit tunnel.
Nat. Chem. Biol., 13, 2017
5WNS
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Crystal Structure of 30S ribosomal subunit from Thermus thermophilus
分子名称: 16S Ribosomal RNA rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
著者DeMirci, H.
登録日2017-08-01
公開日2018-02-21
最終更新日2020-10-21
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献2'-O-methylation in mRNA disrupts tRNA decoding during translation elongation.
Nat. Struct. Mol. Biol., 25, 2018
5WFS
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70S ribosome-EF-Tu H84A complex with GTP and near-cognate tRNA (Complex C4)
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Fislage, M, Frank, J.
登録日2017-07-12
公開日2018-05-02
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-TuH84A.
Nucleic Acids Res., 46, 2018
5WFK
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70S ribosome-EF-Tu H84A complex with GTP and near-cognate tRNA (Complex C3)
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Fislage, M, Frank, J.
登録日2017-07-12
公開日2018-05-02
最終更新日2019-11-20
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-TuH84A.
Nucleic Acids Res., 46, 2018
5WF0
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70S ribosome-EF-Tu H84A complex with GTP and near-cognate tRNA (Complex C2)
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Fislage, M, Frank, J.
登録日2017-07-11
公開日2018-05-02
最終更新日2019-11-20
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-TuH84A.
Nucleic Acids Res., 46, 2018
5WNR
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Crystal Structure of 30S ribosomal subunit from Thermus thermophilus
分子名称: 16S Ribosomal RNA rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
著者DeMirci, H.
登録日2017-08-01
公開日2018-02-21
最終更新日2020-10-21
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献2'-O-methylation in mRNA disrupts tRNA decoding during translation elongation.
Nat. Struct. Mol. Biol., 25, 2018
8T8C
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Crystal structure of the Thermus thermophilus 70S ribosome in complex with protein Y, A-site aminoacyl-tRNA analog ACC-PMN, and P-site formyl-MFI-tripeptidyl-tRNA analog ACCA-IFMf at 2.60A resolution
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ...
著者Thaler, J, Syroegin, E.A, Breuker, K, Polikanov, Y.S, Micura, R.
登録日2023-06-22
公開日2023-07-19
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Practical Synthesis of N -Formylmethionylated Peptidyl-tRNA Mimics.
Acs Chem.Biol., 18, 2023
8T4S
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MERS-CoV Nsp1 protein bound to the Human 40S Ribosomal subunit
分子名称: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
著者Devarkar, S.C, Xiong, Y.
登録日2023-06-09
公開日2023-10-04
最終更新日2023-10-11
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Structural basis for translation inhibition by MERS-CoV Nsp1 reveals a conserved mechanism for betacoronaviruses.
Cell Rep, 42, 2023
8UU9
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Cryo-EM structure of the ratcheted Listeria innocua 70S ribosome (head-swiveled) in complex with HflXr and pe/E-tRNA (structure II-D)
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 5S Ribosomal RNA, ...
著者Seely, S.M, Basu, R.S, Gagnon, M.G.
登録日2023-10-31
公開日2024-02-28
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Mechanistic insights into the alternative ribosome recycling by HflXr.
Nucleic Acids Res., 52, 2024
8RCL
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Escherichia coli paused disome complex (Non-rotated disome interface class 1)
分子名称: 1,4-DIAMINOBUTANE, 16S ribosomal RNA, 23S ribosomal RNA, ...
著者Fluegel, T, Schacherl, M.
登録日2023-12-06
公開日2024-03-13
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3.49 Å)
主引用文献Transient disome complex formation in native polysomes during ongoing protein synthesis captured by cryo-EM.
Nat Commun, 15, 2024
8RCS
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Escherichia coli paused disome complex (Rotated disome interface class 1)
分子名称: 1,4-DIAMINOBUTANE, 16S ribosomal RNA, 23S ribosomal RNA, ...
著者Fluegel, T, Schacherl, M.
登録日2023-12-07
公開日2024-03-06
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (4.46 Å)
主引用文献Transient disome complex formation in native polysomes during ongoing protein synthesis captured by cryo-EM.
Nat Commun, 15, 2024
8URH
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Escherichia coli transcription-translation coupled complex class B (TTC-B) containing RfaH bound to ops signal, mRNA with a 27 nt long spacer, and fMet-tRNAs in E-site and P-site of the ribosome
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ...
著者Molodtsov, V, Wang, C, Ebright, R.H.
登録日2023-10-26
公開日2024-05-29
実験手法ELECTRON MICROSCOPY (5.7 Å)
主引用文献Escherichia coli transcription-translation coupled complex class A (TTC-A) containing RfaH bound to ops signal, mRNA with a 21 nt long spacer, and fMet-tRNAs in E-site and P-site of the ribosome
Nat.Struct.Mol.Biol., 2024
8UPR
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Escherichia coli transcription-translation coupled complex class A (TTC-A) containing RfaH bound to ops signal, mRNA with a 21 nt long spacer, and fMet-tRNAs in E-site and P-site of the ribosome
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ...
著者Molodtsov, V, Wang, C, Ebright, R.H.
登録日2023-10-23
公開日2024-05-29
実験手法ELECTRON MICROSCOPY (5.3 Å)
主引用文献Escherichia coli transcription-translation coupled complex class A (TTC-A) containing RfaH bound to ops signal, mRNA with a 21 nt long spacer, and fMet-tRNAs in E-site and P-site of the ribosome
Nat.Struct.Mol.Biol., 2024
8UQM
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Escherichia coli transcription-translation coupled complex class B (TTC-B) containing RfaH in loaded state, NusA, mRNA with a 24 nt long spacer, and fMet-tRNAs in E-site and P-site of the ribosome
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ...
著者Molodtsov, V, Wang, C, Ebright, R.H.
登録日2023-10-24
公開日2024-05-29
実験手法ELECTRON MICROSCOPY (5.3 Å)
主引用文献Escherichia coli transcription-translation coupled complex class A (TTC-A) containing RfaH bound to ops signal, mRNA with a 21 nt long spacer, and fMet-tRNAs in E-site and P-site of the ribosome
Nat.Struct.Mol.Biol., 2024
8URX
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Escherichia coli transcription-translation coupled complex class B (TTC-B) containing RfaH bound to ops signal, mRNA with a 30 nt long spacer, and fMet-tRNAs in E-site and P-site of the ribosome
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ...
著者Molodtsov, V, Wang, C, Ebright, R.H.
登録日2023-10-27
公開日2024-05-29
実験手法ELECTRON MICROSCOPY (6.6 Å)
主引用文献Escherichia coli transcription-translation coupled complex class A (TTC-A) containing RfaH bound to ops signal, mRNA with a 21 nt long spacer, and fMet-tRNAs in E-site and P-site of the ribosome
Nat.Struct.Mol.Biol., 2024
8UR0
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Escherichia coli transcription-translation coupled complex class B (TTC-B) containing RfaH bound to ops signal, NusA, mRNA with a 24 nt long spacer, and fMet-tRNAs in E-site and P-site of the ribosome
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ...
著者Molodtsov, V, Wang, C, Ebright, R.H.
登録日2023-10-25
公開日2024-05-29
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Escherichia coli transcription-translation coupled complex class A (TTC-A) containing RfaH bound to ops signal, mRNA with a 21 nt long spacer, and fMet-tRNAs in E-site and P-site of the ribosome
Nat.Struct.Mol.Biol., 2024
8SCB
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Terminating ribosome with SRI-41315
分子名称: (2S,4aS)-2-cyclobutyl-10-methyl-3-phenyl-2,10-dihydropyrimido[4,5-b]quinoline-4,5(3H,4aH)-dione, 18S_rRNA, 28S_rRNA, ...
著者Yip, M.C.J, Coelho, J.P.L, Oltion, K, Tauton, J, Shao, S.
登録日2023-04-05
公開日2023-12-27
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Structure and consequences of eRF1 glued to the ribosomal decoding center
To Be Published
8T8B
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Crystal structure of the Thermus thermophilus 70S ribosome in complex with protein Y, A-site aminoacyl-tRNA analog ACC-PMN, and P-site formyl-MAI-tripeptidyl-tRNA analog ACCA-IAMf at 2.65A resolution
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ...
著者Thaler, J, Syroegin, E.A, Breuker, K, Polikanov, Y.S, Micura, R.
登録日2023-06-22
公開日2023-07-19
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Practical Synthesis of N -Formylmethionylated Peptidyl-tRNA Mimics.
Acs Chem.Biol., 18, 2023

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件を2024-07-03に公開中

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