7ZUW
| Structure of RQT (C1) bound to the stalled ribosome in a disome unit from S. cerevisiae | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | 著者 | Best, K.M, Ikeuchi, K, Kater, L, Best, D.M, Musial, J, Matsuo, Y, Berninghausen, O, Becker, T, Inada, T, Beckmann, R. | 登録日 | 2022-05-13 | 公開日 | 2023-02-22 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Structural basis for clearing of ribosome collisions by the RQT complex. Nat Commun, 14, 2023
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8AYE
| E. coli 70S ribosome bound to thermorubin and fMet-tRNA | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Sanyal, S, Parajuli, N.P, Emmerich, A.G. | 登録日 | 2022-09-02 | 公開日 | 2023-03-01 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (1.96 Å) | 主引用文献 | Antibiotic thermorubin tethers ribosomal subunits and impedes A-site interactions to perturb protein synthesis in bacteria. Nat Commun, 14, 2023
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7Y7D
| Structure of the Bacterial Ribosome with human tRNA Asp(Q34) and mRNA(GAU) | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T. | 登録日 | 2022-06-22 | 公開日 | 2023-10-25 | 最終更新日 | 2023-12-27 | 実験手法 | ELECTRON MICROSCOPY (2.58 Å) | 主引用文献 | Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth. Cell, 186, 2023
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7Y7C
| Structure of the Bacterial Ribosome with human tRNA Asp(G34) and mRNA(GAU) | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T. | 登録日 | 2022-06-22 | 公開日 | 2023-10-25 | 最終更新日 | 2023-12-27 | 実験手法 | ELECTRON MICROSCOPY (2.51 Å) | 主引用文献 | Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth. Cell, 186, 2023
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7Y7F
| Structure of the Bacterial Ribosome with human tRNA Asp(ManQ34) and mRNA(GAC) | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T. | 登録日 | 2022-06-22 | 公開日 | 2023-10-25 | 最終更新日 | 2023-12-27 | 実験手法 | ELECTRON MICROSCOPY (2.43 Å) | 主引用文献 | Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth. Cell, 186, 2023
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7Y7E
| Structure of the Bacterial Ribosome with human tRNA Asp(ManQ34) and mRNA(GAU) | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T. | 登録日 | 2022-06-22 | 公開日 | 2023-10-25 | 最終更新日 | 2023-12-27 | 実験手法 | ELECTRON MICROSCOPY (2.41 Å) | 主引用文献 | Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth. Cell, 186, 2023
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7Y7G
| Structure of the Bacterial Ribosome with human tRNA Tyr(GalQ34) and mRNA(UAU) | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T. | 登録日 | 2022-06-22 | 公開日 | 2023-10-25 | 最終更新日 | 2023-12-27 | 実験手法 | ELECTRON MICROSCOPY (2.34 Å) | 主引用文献 | Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth. Cell, 186, 2023
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7Y7H
| Structure of the Bacterial Ribosome with human tRNA Tyr(GalQ34) and mRNA(UAC) | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T. | 登録日 | 2022-06-22 | 公開日 | 2023-10-25 | 最終更新日 | 2023-12-27 | 実験手法 | ELECTRON MICROSCOPY (2.51 Å) | 主引用文献 | Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth. Cell, 186, 2023
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8AKN
| Cryo-EM structure of the proline-rich antimicrobial peptide drosocin bound to the terminating ribosome | 分子名称: | 16S ribosomal RNA, 2-acetamido-2-deoxy-alpha-D-galactopyranose, 23S ribosomal RNA, ... | 著者 | Koller, T.O, Morici, M, Wilson, D.N. | 登録日 | 2022-07-30 | 公開日 | 2023-03-08 | 最終更新日 | 2023-09-06 | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | 主引用文献 | Structural basis for translation inhibition by the glycosylated drosocin peptide. Nat.Chem.Biol., 19, 2023
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8AM9
| Cryo-EM structure of the proline-rich antimicrobial peptide drosocin bound to the elongating ribosome | 分子名称: | 16S ribosomal RNA, 2-acetamido-2-deoxy-alpha-D-galactopyranose, 23S ribosomal RNA, ... | 著者 | Koller, T.O, Morici, M, Wilson, D.N. | 登録日 | 2022-08-03 | 公開日 | 2023-03-08 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Structural basis for translation inhibition by the glycosylated drosocin peptide. Nat.Chem.Biol., 19, 2023
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8AUV
| Cryo-EM structure of the plant 40S subunit | 分子名称: | 18S rRNA, MAGNESIUM ION, POTASSIUM ION, ... | 著者 | Smirnova, J, Loerke, J, Kleinau, G, Schmidt, A, Buerger, J, Meyer, E.H, Mielke, T, Scheerer, P, Bock, R, Spahn, C.M.T, Zoschke, R. | 登録日 | 2022-08-25 | 公開日 | 2023-06-07 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.38 Å) | 主引用文献 | Structure of the actively translating plant 80S ribosome at 2.2 angstrom resolution. Nat.Plants, 9, 2023
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8B2L
| Cryo-EM structure of the plant 80S ribosome | 分子名称: | 18S rRNA, 25S rRNA, 30S ribosomal protein S15, ... | 著者 | Smirnova, J, Loerke, J, Kleinau, G, Schmidt, A, Buerger, J, Meyer, E.H, Mielke, T, Scheerer, P, Bock, R, Spahn, C.M.T, Zoschke, R. | 登録日 | 2022-09-14 | 公開日 | 2023-08-23 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.2 Å) | 主引用文献 | Structure of the actively translating plant 80S ribosome at 2.2 angstrom resolution. Nat.Plants, 9, 2023
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8B7Y
| Cryo-EM structure of the E.coli 70S ribosome in complex with the antibiotic Myxovalargin B. | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Koller, T.O, Graf, M, Wilson, D.N. | 登録日 | 2022-10-03 | 公開日 | 2023-01-25 | 最終更新日 | 2023-02-01 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | The Myxobacterial Antibiotic Myxovalargin: Biosynthesis, Structural Revision, Total Synthesis, and Molecular Characterization of Ribosomal Inhibition. J.Am.Chem.Soc., 145, 2023
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9BDN
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9F1C
| Mammalian quaternary complex of a translating 80S ribosome, NAC, MetAP1 and NatA/E | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... | 著者 | Yudin, D, Scaiola, A, Ban, N. | 登録日 | 2024-04-18 | 公開日 | 2024-08-21 | 最終更新日 | 2024-09-04 | 実験手法 | ELECTRON MICROSCOPY (3.78 Å) | 主引用文献 | NAC guides a ribosomal multienzyme complex for nascent protein processing. Nature, 2024
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8WID
| Cryo- EM structure of Mycobacterium smegmatis 30S ribosomal subunit (body 2) of 70S ribosome, E- tRNA and RafH. | 分子名称: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | 著者 | Kumar, N, Sharma, S, Kaushal, P.S. | 登録日 | 2023-09-24 | 公開日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Cryo- EM structure of the mycobacterial 70S ribosome in complex with ribosome hibernation promotion factor RafH. Nat Commun, 15, 2024
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8VTX
| Crystal structure of the A2058-N6-dimethylated Thermus thermophilus 70S ribosome in complex with macrolone MCX-128, mRNA, aminoacylated A-site Phe-tRNAphe, aminoacylated P-site fMet-tRNAmet, and deacylated E-site tRNAphe at 2.40A resolution | 分子名称: | 1-cyclopropyl-7-(4-{4-[({[(3aR,4R,7R,8S,9S,10R,11R,13R,14E,15S,15aR)-10-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-4-ethyl-11-methoxy-14-(methoxyimino)-3a,7,9,11,13,15-hexamethyl-2,6-dioxododecahydro-2H,4H-[1,3]dioxolo[4,5-c]oxacyclotetradecin-8-yl]oxy}carbonyl)amino]butyl}piperazin-1-yl)-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (non-preferred name), 16S Ribosomal RNA, 23S Ribosomal RNA, ... | 著者 | Aleksandrova, E.V, Ma, C.-X, Klepacki, D, Alizadeh, F, Vazquez-Laslop, N, Liang, J.-H, Polikanov, Y.S, Mankin, A.S. | 登録日 | 2024-01-27 | 公開日 | 2024-08-07 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Macrolones target bacterial ribosomes and DNA gyrase and can evade resistance mechanisms. Nat.Chem.Biol., 2024
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8VTY
| Crystal structure of the wild-type Thermus thermophilus 70S ribosome in complex with ciprofloxacin and protein Y at 2.60A resolution | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1-CYCLOPROPYL-6-FLUORO-4-OXO-7-PIPERAZIN-1-YL-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID, 16S Ribosomal RNA, ... | 著者 | Aleksandrova, E.V, Ma, C.-X, Klepacki, D, Alizadeh, F, Vazquez-Laslop, N, Liang, J.-H, Polikanov, Y.S, Mankin, A.S. | 登録日 | 2024-01-27 | 公開日 | 2024-08-07 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Macrolones target bacterial ribosomes and DNA gyrase and can evade resistance mechanisms. Nat.Chem.Biol., 2024
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8XSX
| Cryo-EM structure of the human 80S ribosome with Tigecycline, E-tRNA, SERBP1 and eEF2 | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | 著者 | Li, X, Wang, M, Cheng, J. | 登録日 | 2024-01-10 | 公開日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | 主引用文献 | Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15, 2024
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9F1D
| Mammalian quaternary complex of a translating 80S ribosome, NAC, MetAP1 and NatA/E-HYPK | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... | 著者 | Yudin, D, Scaiola, A, Ban, N. | 登録日 | 2024-04-18 | 公開日 | 2024-08-21 | 最終更新日 | 2024-09-04 | 実験手法 | ELECTRON MICROSCOPY (3.26 Å) | 主引用文献 | NAC guides a ribosomal multienzyme complex for nascent protein processing. Nature, 2024
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8Y38
| Cryo-EM structure of Staphylococcus aureus 70S ribosome (strain 15B196) in complex with MCX-190. | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 5S ribosomal RNA, ... | 著者 | Li, Y, Lu, G, Li, J, Pei, X, Lin, J. | 登録日 | 2024-01-28 | 公開日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (2.58 Å) | 主引用文献 | Synthetic macrolides overcoming MLS B K-resistant pathogens. Cell Discov, 10, 2024
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8WQ4
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8WKP
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8WI9
| Cryo- EM structure of Mycobacterium smegmatis 30S ribosomal subunit (body 2) of 70S ribosome, bS1 and RafH. | 分子名称: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | 著者 | Kumar, N, Sharma, S, Kaushal, P.S. | 登録日 | 2023-09-24 | 公開日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Cryo- EM structure of the mycobacterial 70S ribosome in complex with ribosome hibernation promotion factor RafH. Nat Commun, 15, 2024
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8XXL
| Cryo-EM structure of the human 40S ribosome with PDCD4 | 分子名称: | 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | 著者 | Ye, X, Huang, Z, Li, Y, Wang, M, Cheng, J. | 登録日 | 2024-01-18 | 公開日 | 2024-05-01 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Human tumor suppressor PDCD4 directly interacts with ribosomes to repress translation. Cell Res., 34, 2024
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