2XZZ
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![BU of 2xzz by Molmil](/molmil-images/mine/2xzz) | Crystal structure of the human transglutaminase 1 beta-barrel domain | 分子名称: | PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE K | 著者 | Vollmar, M, Krysztofinska, E, Krojer, T, Yue, W.W, Cooper, C, Kavanagh, K, Allerston, C, Chaikuad, A, von Delft, F, Arrowsmith, C.H, Weigelt, J, Edwards, A, Bountra, C, Oppermann, U. | 登録日 | 2010-11-30 | 公開日 | 2011-01-26 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal Structure of the Human Transglutaminase 1 Beta-Barrel Domain To be Published
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6KZB
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![BU of 6kzb by Molmil](/molmil-images/mine/6kzb) | Transglutaminase2 complexed with calcium | 分子名称: | CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, Protein-glutamine gamma-glutamyltransferase 2 | 著者 | Park, H.H, Kim, C.M. | 登録日 | 2019-09-23 | 公開日 | 2020-12-09 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.55 Å) | 主引用文献 | Competitive Binding of Magnesium to Calcium Binding Sites Reciprocally Regulates Transamidase and GTP Hydrolysis Activity of Transglutaminase 2. Int J Mol Sci, 21, 2020
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3LY6
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![BU of 3ly6 by Molmil](/molmil-images/mine/3ly6) | |
4KTY
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![BU of 4kty by Molmil](/molmil-images/mine/4kty) | Fibrin-stabilizing factor with a bound ligand | 分子名称: | CALCIUM ION, Coagulation factor XIII A chain, GLYCEROL, ... | 著者 | Stieler, M, Heine, A, Klebe, G. | 登録日 | 2013-05-21 | 公開日 | 2013-12-04 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Structure of Active Coagulation Factor XIII Triggered by Calcium Binding: Basis for the Design of Next-Generation Anticoagulants. Angew.Chem.Int.Ed.Engl., 52, 2013
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4PYG
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![BU of 4pyg by Molmil](/molmil-images/mine/4pyg) | Transglutaminase2 complexed with GTP | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, Protein-glutamine gamma-glutamyltransferase 2 | 著者 | Park, H.H, Jang, T.H. | 登録日 | 2014-03-27 | 公開日 | 2015-02-11 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal structure of transglutaminase 2 with GTP complex and amino acid sequence evidence of evolution of GTP binding site. Plos One, 9, 2014
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2Q3Z
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![BU of 2q3z by Molmil](/molmil-images/mine/2q3z) | Transglutaminase 2 undergoes large conformational change upon activation | 分子名称: | Polypeptide, SULFATE ION, Transglutaminase 2 | 著者 | Strop, P, Pinkas, D.M, Brunger, A.T, Khosla, C. | 登録日 | 2007-05-30 | 公開日 | 2007-10-23 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Transglutaminase 2 undergoes a large conformational change upon activation Plos Biol., 5, 2007
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8TR9
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![BU of 8tr9 by Molmil](/molmil-images/mine/8tr9) | Cryo-EM structure of transglutaminase 2 bound to GDP | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Protein-glutamine gamma-glutamyltransferase 2 | 著者 | Aplin, C, Cerione, R.A. | 登録日 | 2023-08-09 | 公開日 | 2024-07-31 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Conformational activation and inhibition of transglutaminase 2 determined by static and time resolved small-angle X-ray scattering and cryoelectron microscopy To Be Published
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6A8P
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![BU of 6a8p by Molmil](/molmil-images/mine/6a8p) | |
1QRK
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![BU of 1qrk by Molmil](/molmil-images/mine/1qrk) | HUMAN FACTOR XIII WITH STRONTIUM BOUND IN THE ION SITE | 分子名称: | PROTEIN (COAGULATION FACTOR XIII), STRONTIUM ION | 著者 | Fox, B.A, Yee, V.C, Pederson, L.C, Le Trong, I, Bishop, P.D, Stenkamp, R.E, Teller, D.C. | 登録日 | 1999-06-14 | 公開日 | 1999-07-02 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Identification of the calcium binding site and a novel ytterbium site in blood coagulation factor XIII by x-ray crystallography. J.Biol.Chem., 274, 1999
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3S3J
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![BU of 3s3j by Molmil](/molmil-images/mine/3s3j) | |
3S3S
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![BU of 3s3s by Molmil](/molmil-images/mine/3s3s) | |
3S3P
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![BU of 3s3p by Molmil](/molmil-images/mine/3s3p) | |
9BC2
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![BU of 9bc2 by Molmil](/molmil-images/mine/9bc2) | Transglutaminase 2 - Open State | 分子名称: | CHLORIDE ION, HB-225 (gluten peptidomimetic TG2 inhibitor), Protein-glutamine gamma-glutamyltransferase 2, ... | 著者 | Mathews, I.I, Sewa, A, Khosla, C. | 登録日 | 2024-04-07 | 公開日 | 2024-07-03 | 最終更新日 | 2024-07-17 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Structural and mechanistic analysis of Ca 2+ -dependent regulation of transglutaminase 2 activity using a Ca 2+ -bound intermediate state. Proc.Natl.Acad.Sci.USA, 121, 2024
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9BC4
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![BU of 9bc4 by Molmil](/molmil-images/mine/9bc4) | Transglutaminase 2 - Intermediate State | 分子名称: | CALCIUM ION, GLYCEROL, HB-225 (gluten peptidomimetic TG2 inhibitor), ... | 著者 | Sewa, A.S, Mathews, I.I, Khosla, C. | 登録日 | 2024-04-07 | 公開日 | 2024-07-03 | 最終更新日 | 2024-07-17 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | Structural and mechanistic analysis of Ca 2+ -dependent regulation of transglutaminase 2 activity using a Ca 2+ -bound intermediate state. Proc.Natl.Acad.Sci.USA, 121, 2024
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9BC3
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![BU of 9bc3 by Molmil](/molmil-images/mine/9bc3) | Transglutaminase 2 - Alternate state | 分子名称: | CALCIUM ION, HB-225 (gluten peptidomimetic TG2 inhibitor), Protein-glutamine gamma-glutamyltransferase 2 | 著者 | Mathews, I.I, Sewa, A.S, Khosla, C. | 登録日 | 2024-04-07 | 公開日 | 2024-07-03 | 最終更新日 | 2024-07-17 | 実験手法 | X-RAY DIFFRACTION (2.52 Å) | 主引用文献 | Structural and mechanistic analysis of Ca 2+ -dependent regulation of transglutaminase 2 activity using a Ca 2+ -bound intermediate state. Proc.Natl.Acad.Sci.USA, 121, 2024
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8OXW
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![BU of 8oxw by Molmil](/molmil-images/mine/8oxw) | |
8OXV
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![BU of 8oxv by Molmil](/molmil-images/mine/8oxv) | |
8OXY
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![BU of 8oxy by Molmil](/molmil-images/mine/8oxy) | |
1EX0
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![BU of 1ex0 by Molmil](/molmil-images/mine/1ex0) | HUMAN FACTOR XIII, MUTANT W279F ZYMOGEN | 分子名称: | CALCIUM ION, COAGULATION FACTOR XIII A CHAIN, PHOSPHATE ION, ... | 著者 | Garzon, R.J, Pratt, K.P, Bishop, P.D, Le Trong, I, Stenkamp, R.E, Teller, D.C. | 登録日 | 2000-04-28 | 公開日 | 2003-12-23 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Tryptophan 279 is Essential for the Transglutaminase Activity of Coagulation Factor XIII: Functional and Structural Characterization To be Published
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1EVU
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![BU of 1evu by Molmil](/molmil-images/mine/1evu) | HUMAN FACTOR XIII WITH CALCIUM BOUND IN THE ION SITE | 分子名称: | CALCIUM ION, COAGULATION FACTOR XIII, S-1,2-PROPANEDIOL | 著者 | Garzon, R.J, Pratt, K.P, Bishop, P.D, Le Trong, I, Stenkamp, R.E, Teller, D.C. | 登録日 | 2000-04-20 | 公開日 | 2000-05-10 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Tryptophan 279 is Essential for the Transglutaminase Activity of Coagulation Factor XIII: Functional and Structural Characterization To Be Published
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1F13
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![BU of 1f13 by Molmil](/molmil-images/mine/1f13) | |
5MHM
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![BU of 5mhm by Molmil](/molmil-images/mine/5mhm) | |
5MHO
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5MHN
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![BU of 5mhn by Molmil](/molmil-images/mine/5mhn) | |
8CSL
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![BU of 8csl by Molmil](/molmil-images/mine/8csl) | Sub-tomogram averaging of erythrocyte ankyrin-1 complex | 分子名称: | Ammonium transporter Rh type A, Ankyrin-1, Band 3 anion transport protein, ... | 著者 | Vallese, F, Kim, K, Yen, L.Y, Johnston, J.D, Noble, A.J, Cali, T, Clarke, O.B. | 登録日 | 2022-05-12 | 公開日 | 2022-07-20 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (25 Å) | 主引用文献 | Architecture of the human erythrocyte ankyrin-1 complex. Nat.Struct.Mol.Biol., 29, 2022
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