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8TR9

Cryo-EM structure of transglutaminase 2 bound to GDP

Summary for 8TR9
Entry DOI10.2210/pdb8tr9/pdb
EMDB information41574
DescriptorProtein-glutamine gamma-glutamyltransferase 2, GUANOSINE-5'-DIPHOSPHATE (2 entities in total)
Functional Keywordsgdp, complex, signaling, g-protein, cancer, cryo-em, transferase
Biological sourceHomo sapiens (human)
Total number of polymer chains1
Total formula weight77855.88
Authors
Aplin, C.,Cerione, R.A. (deposition date: 2023-08-09, release date: 2024-07-31)
Primary citationAplin, C.,Zielinski, K.A.,Pabit, S.,Ogunribido, D.,Katt, W.P.,Pollack, L.,Cerione, R.A.,Milano, S.K.
Conformational activation and inhibition of transglutaminase 2 determined by static and time resolved small-angle X-ray scattering and cryoelectron microscopy
To Be Published,
Experimental method
ELECTRON MICROSCOPY (3.2 Å)
Structure validation

223532

PDB entries from 2024-08-07

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