4KTY

Fibrin-stabilizing factor with a bound ligand

Summary for 4KTY

• Entry DOI: 10.2210/pdb4kty/pdb
• Related: 1F13
• Related PRD ID: PRD_001125
• Descriptor: Coagulation factor XIII A chain, Peptide-like ligand, CALCIUM ION, ... (6 entities in total)
• Functional Keywords: transglutaminase, coagulation, transferase, acyltransferase, ligand, calcium ions, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: P00488
• Total number of polymer chains: 4
• Total formula weight: 171653.84

Authors

Stieler, M.,Heine, A.,Klebe, G. (deposition date: 2013-05-21, release date: 2013-12-04, Last modification date: 2023-11-15)

• Primary citation: Stieler, M.,Weber, J.,Hils, M.,Kolb, P.,Heine, A.,Buchold, C.,Pasternack, R.,Klebe, G.; Structure of Active Coagulation Factor XIII Triggered by Calcium Binding: Basis for the Design of Next-Generation Anticoagulants.; Angew.Chem.Int.Ed.Engl., 52:11930-11934, 2013; PubMed: 24115223; DOI: 10.1002/anie.201305133

Experimental method

X-RAY DIFFRACTION (1.98 Å)