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PDB: 74 件
7TNN
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Complex GGNN of AMPA-subtype iGluR GluA2 in complex with auxiliary subunit gamma2 (Stargazin) at low glutamate concentration (20 uM) in the presence of cyclothiazide (100 uM)
分子名称: CYCLOTHIAZIDE, GLUTAMIC ACID, Isoform Flip of Glutamate receptor 2,Voltage-dependent calcium channel gamma-3 subunit chimera
著者Yelshanskaya, M.V, Sobolevsky, A.I.
登録日2022-01-21
公開日2022-04-20
最終更新日2022-05-18
実験手法ELECTRON MICROSCOPY (3.91 Å)
主引用文献Opening of glutamate receptor channel to subconductance levels.
Nature, 605, 2022
7TNM
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Complex GNGN2 of AMPA-subtype iGluR GluA2 in complex with auxiliary subunit gamma2 (Stargazin) at low glutamate concentration (20 uM) in the presence of cyclothiazide (100 uM)
分子名称: CYCLOTHIAZIDE, GLUTAMIC ACID, Isoform Flip of Glutamate receptor 2,Voltage-dependent calcium channel gamma-3 subunit chimera
著者Yelshanskaya, M.V, Sobolevsky, A.I.
登録日2022-01-21
公開日2022-04-20
最終更新日2022-05-18
実験手法ELECTRON MICROSCOPY (4.74 Å)
主引用文献Opening of glutamate receptor channel to subconductance levels.
Nature, 605, 2022
7OCA
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Resting state full-length GluA1/A2 heterotertramer in complex with TARP gamma 8 and CNIH2
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Zhang, D, Watson, J.F, Matthews, P.M, Cais, O, Greger, I.H.
登録日2021-04-26
公開日2021-06-09
最終更新日2021-06-30
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Gating and modulation of a hetero-octameric AMPA glutamate receptor.
Nature, 594, 2021
7OCD
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BU of 7ocd by Molmil
Resting state GluA1/A2 heterotetramer in complex with auxiliary subunit TARP gamma 8 (LBD-TMD)
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 6-nitro-2,3-bis(oxidanylidene)-1,4-dihydrobenzo[f]quinoxaline-7-sulfonamide, Glutamate receptor 2, ...
著者Zhang, D, Watson, J.F, Matthews, P.M, Cais, O, Greger, I.H.
登録日2021-04-26
公開日2021-06-09
最終更新日2021-06-30
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Gating and modulation of a hetero-octameric AMPA glutamate receptor.
Nature, 594, 2021
7OCE
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BU of 7oce by Molmil
Resting state GluA1/A2 AMPA receptor in complex with TARP gamma 8 and CNIH2 (LBD-TMD)
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 6-nitro-2,3-bis(oxidanylidene)-1,4-dihydrobenzo[f]quinoxaline-7-sulfonamide, CHOLESTEROL, ...
著者Zhang, D, Watson, J.F, Matthews, P.M, Cais, O, Greger, I.H.
登録日2021-04-26
公開日2021-06-09
最終更新日2021-06-30
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Gating and modulation of a hetero-octameric AMPA glutamate receptor.
Nature, 594, 2021
7OCF
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BU of 7ocf by Molmil
Active state GluA1/A2 AMPA receptor in complex with TARP gamma 8 and CNIH2 (LBD-TMD)
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CYCLOTHIAZIDE, GLUTAMIC ACID, ...
著者Zhang, D, Watson, J.F, Matthews, P.M, Cais, O, Greger, I.H.
登録日2021-04-26
公開日2021-06-09
最終更新日2021-06-30
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Gating and modulation of a hetero-octameric AMPA glutamate receptor.
Nature, 594, 2021
8FQ1
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BU of 8fq1 by Molmil
GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma2, with 150mM CaCl2, 330uM CTZ, and 100mM L-glutamate (Open-Ca150)
分子名称: CALCIUM ION, Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit
著者Nakagawa, T.
登録日2023-01-05
公開日2024-02-28
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (5.59 Å)
主引用文献The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nat.Struct.Mol.Biol., 31, 2024
8FQ5
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GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma2, with 140mM NMDG, 330uM CTZ, and 100mM L-glutamate (Open-Na110)
分子名称: CHLORIDE ION, Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit
著者Nakagawa, T.
登録日2023-01-05
公開日2024-02-28
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (2.34 Å)
主引用文献The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nat.Struct.Mol.Biol., 31, 2024
8FPS
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BU of 8fps by Molmil
GluA2 flip Q isoform N619K mutant of AMPA receptor in complex with gain-of-function TARP gamma-2, with 10mM CaCl2, 150mM NaCl, 1mM MgCl2, 330uM CTZ, and 100mM glutamate (Open-CaNaMg/N619K)
分子名称: CHLORIDE ION, Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit
著者Nakagawa, T.
登録日2023-01-05
公開日2024-02-28
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (2.38 Å)
主引用文献The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nat.Struct.Mol.Biol., 31, 2024
8FP4
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BU of 8fp4 by Molmil
GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 500mM NaCl, 330uM CTZ, and 100mM glutamate (Open-Na610)
分子名称: CHLORIDE ION, Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit
著者Nakagawa, T.
登録日2023-01-04
公開日2024-02-28
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (2.4 Å)
主引用文献The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nat.Struct.Mol.Biol., 31, 2024
8FQB
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BU of 8fqb by Molmil
GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma2, with 10mM CaCl2, 140mM NMDG, 330uM CTZ, and 100mM L-glutamate (Open-Ca10)
分子名称: CALCIUM ION, CHLORIDE ION, Glutamate receptor 2, ...
著者Nakagawa, T.
登録日2023-01-05
公開日2024-02-28
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (2.36 Å)
主引用文献The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nat.Struct.Mol.Biol., 31, 2024
8FPG
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BU of 8fpg by Molmil
GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 10mM CaCl2, 150mM NaCl, 1mM MgCl2, 330uM CTZ, and 100uM CNQX (Closed-CaNaMg)
分子名称: CHLORIDE ION, Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit
著者Nakagawa, T.
登録日2023-01-04
公開日2024-02-28
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (2.32 Å)
主引用文献The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nat.Struct.Mol.Biol., 31, 2024
8FP9
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BU of 8fp9 by Molmil
GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 10mM CaCl2, 150mM NaCl, 1mM MgCl2, 330uM CTZ, and 100mM glutamate (Open-CaNaMg)
分子名称: CALCIUM ION, CHLORIDE ION, Glutamate receptor 2, ...
著者Nakagawa, T.
登録日2023-01-04
公開日2024-02-28
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (2.44 Å)
主引用文献The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nat.Struct.Mol.Biol., 31, 2024
8FQF
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BU of 8fqf by Molmil
GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 150mM NaCl, 330uM CTZ, and 100mM glutamate (Open-Na260)
分子名称: CHLORIDE ION, Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit
著者Nakagawa, T.
登録日2023-01-06
公開日2024-02-28
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (2.29 Å)
主引用文献The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nat.Struct.Mol.Biol., 31, 2024
8P3Y
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BU of 8p3y by Molmil
Homomeric GluA2 flip R/G-edited Q/R-edited F231A mutant in tandem with TARP gamma-2, desensitized conformation 3
分子名称: Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit
著者Krieger, J.M, Zhang, D, Yamashita, K, Greger, I.H.
登録日2023-05-18
公開日2023-08-30
最終更新日2023-10-11
実験手法ELECTRON MICROSCOPY (3.55 Å)
主引用文献Structural mobility tunes signalling of the GluA1 AMPA glutamate receptor.
Nature, 621, 2023
8P3Z
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BU of 8p3z by Molmil
Homomeric GluA2 flip R/G-edited Q/R-edited F231A mutant in tandem with TARP gamma-2, desensitized conformation 2
分子名称: Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit
著者Krieger, J.M, Zhang, D, Yamashita, K, Greger, I.H.
登録日2023-05-18
公開日2023-08-30
最終更新日2023-10-11
実験手法ELECTRON MICROSCOPY (3.46 Å)
主引用文献Structural mobility tunes signalling of the GluA1 AMPA glutamate receptor.
Nature, 621, 2023
8P3X
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BU of 8p3x by Molmil
Homomeric GluA2 flip R/G-edited Q/R-edited F231A mutant in tandem with TARP gamma-2, desensitized conformation 1
分子名称: Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit
著者Krieger, J.M, Zhang, D, Yamashita, K, Greger, I.H.
登録日2023-05-18
公開日2023-08-30
最終更新日2023-10-11
実験手法ELECTRON MICROSCOPY (3.36 Å)
主引用文献Structural mobility tunes signalling of the GluA1 AMPA glutamate receptor.
Nature, 621, 2023
8P3U
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BU of 8p3u by Molmil
Homomeric GluA1 in tandem with TARP gamma-3, desensitized conformation 2
分子名称: Glutamate receptor 1 flip isoform, Voltage-dependent calcium channel gamma-3 subunit
著者Zhang, D, Krieger, J.M, Greger, I.H.
登録日2023-05-18
公開日2023-08-30
最終更新日2023-10-11
実験手法ELECTRON MICROSCOPY (3.77 Å)
主引用文献Structural mobility tunes signalling of the GluA1 AMPA glutamate receptor.
Nature, 621, 2023
8P3V
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BU of 8p3v by Molmil
Homomeric GluA1 in tandem with TARP gamma-3, desensitized conformation 3
分子名称: Glutamate receptor 1 flip isoform, Voltage-dependent calcium channel gamma-3 subunit
著者Zhang, D, Krieger, J.M, Yamashita, K, Greger, I.H.
登録日2023-05-18
公開日2023-08-30
最終更新日2023-10-11
実験手法ELECTRON MICROSCOPY (3.53 Å)
主引用文献Structural mobility tunes signalling of the GluA1 AMPA glutamate receptor.
Nature, 621, 2023
8P3W
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Homomeric GluA1 in tandem with TARP gamma-3, desensitized conformation 4
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, Glutamate receptor 1 flip isoform, ...
著者Zhang, D, Krieger, J.M, Yamashita, K, Greger, I.
登録日2023-05-18
公開日2023-08-30
最終更新日2023-10-11
実験手法ELECTRON MICROSCOPY (3.53 Å)
主引用文献Structural mobility tunes signalling of the GluA1 AMPA glutamate receptor.
Nature, 621, 2023
8P3Q
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BU of 8p3q by Molmil
Homomeric GluA2 flip R/G-unedited Q/R-edited F231A mutant in tandem with TARP gamma-2, desensitized conformation 3
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, Glutamate receptor 2, ...
著者Zhang, D, Krieger, J.M, Yamashita, K, Greger, I.
登録日2023-05-18
公開日2023-08-30
最終更新日2023-10-11
実験手法ELECTRON MICROSCOPY (2.95 Å)
主引用文献Structural mobility tunes signalling of the GluA1 AMPA glutamate receptor.
Nature, 621, 2023
8P3S
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BU of 8p3s by Molmil
Homomeric GluA2 flip R/G-unedited Q/R-edited F231A mutant in tandem with TARP gamma-2, desensitized conformation 2
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, Glutamate receptor 2, ...
著者Zhang, D, Krieger, J.M, Yamashita, K, Greger, I.
登録日2023-05-18
公開日2023-08-30
最終更新日2023-10-11
実験手法ELECTRON MICROSCOPY (2.95 Å)
主引用文献Structural mobility tunes signalling of the GluA1 AMPA glutamate receptor.
Nature, 621, 2023
8P3T
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BU of 8p3t by Molmil
Homomeric GluA1 in tandem with TARP gamma-3, desensitized conformation 1
分子名称: Glutamate receptor 1 flip isoform, Voltage-dependent calcium channel gamma-3 subunit
著者Zhang, D, Krieger, J, Yamashita, K, Greger, I.
登録日2023-05-18
公開日2023-08-30
最終更新日2023-10-11
実験手法ELECTRON MICROSCOPY (3.39 Å)
主引用文献Structural mobility tunes signalling of the GluA1 AMPA glutamate receptor.
Nature, 621, 2023
8PIV
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BU of 8piv by Molmil
Homomeric GluA2 flip R/G-unedited Q/R-edited F231A mutant in tandem with TARP gamma-2, desensitized conformation 1
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, Glutamate receptor, ...
著者Zhang, D, Krieger, J.M, Yamashita, K, Greger, I.H.
登録日2023-06-22
公開日2023-08-30
最終更新日2023-10-11
実験手法ELECTRON MICROSCOPY (3.46 Å)
主引用文献Structural mobility tunes signalling of the GluA1 AMPA glutamate receptor.
Nature, 621, 2023
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