6LN6
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![BU of 6ln6 by Molmil](/molmil-images/mine/6ln6) | CryoEM structure of SERCA2b T1032stop in E1-2Ca2+-AMPPCP (class2) | 分子名称: | CALCIUM ION, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... | 著者 | Zhang, Y, Tsutsumi, A, Watanabe, S, Inaba, K. | 登録日 | 2019-12-28 | 公開日 | 2020-08-26 | 最終更新日 | 2020-09-16 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Cryo-EM structures of SERCA2b reveal the mechanism of regulation by the luminal extension tail. Sci Adv, 6, 2020
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6LLE
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![BU of 6lle by Molmil](/molmil-images/mine/6lle) | CryoEM structure of SERCA2b WT in E1-2Ca2+-AMPPCP state. | 分子名称: | CALCIUM ION, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... | 著者 | Zhang, Y, Tsutsumi, A, Watanabe, S, Inaba, K. | 登録日 | 2019-12-23 | 公開日 | 2020-08-26 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Cryo-EM structures of SERCA2b reveal the mechanism of regulation by the luminal extension tail. Sci Adv, 6, 2020
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6LLY
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![BU of 6lly by Molmil](/molmil-images/mine/6lly) | CryoEM structure of SERCA2b WT in E2-BeF3- state | 分子名称: | BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 | 著者 | Zhang, Y, Tsutsumi, A, Watanabe, S, Inaba, K. | 登録日 | 2019-12-24 | 公開日 | 2020-08-26 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Cryo-EM structures of SERCA2b reveal the mechanism of regulation by the luminal extension tail. Sci Adv, 6, 2020
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5XA9
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![BU of 5xa9 by Molmil](/molmil-images/mine/5xa9) | Complete structure factors and an atomic model of the calcium pump (SERCA1A) and associated phospholipids in the E2-ALF-(TG) crystals of C2 symmetry | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, MAGNESIUM ION, OCTANOIC ACID [3S-[3ALPHA, ... | 著者 | Norimatsu, Y, Hasegawa, K, Shimizu, N, Toyoshima, C. | 登録日 | 2017-03-11 | 公開日 | 2017-06-14 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Protein-phospholipid interplay revealed with crystals of a calcium pump. Nature, 545, 2017
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5XA7
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![BU of 5xa7 by Molmil](/molmil-images/mine/5xa7) | Complete structure factors and an atomic model of the calcium pump (SERCA1A) and associated phospholipids in the E1-2CA2+ crystals | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CALCIUM ION, SODIUM ION, ... | 著者 | Norimatsu, Y, Hasegawa, K, Shimizu, N, Toyoshima, C. | 登録日 | 2017-03-11 | 公開日 | 2017-05-17 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Protein-phospholipid interplay revealed with crystals of a calcium pump. Nature, 545, 2017
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5XAB
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![BU of 5xab by Molmil](/molmil-images/mine/5xab) | Complete structure factors and an atomic model of the calcium pump (SERCA1A) and associated phospholipids in the E2(TG) crystals | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, OCTANOIC ACID [3S-[3ALPHA, 3ABETA, ... | 著者 | Norimatsu, Y, Hasegawa, K, Shimizu, N, Toyoshima, C. | 登録日 | 2017-03-11 | 公開日 | 2017-06-07 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Protein-phospholipid interplay revealed with crystals of a calcium pump. Nature, 545, 2017
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5YLV
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![BU of 5ylv by Molmil](/molmil-images/mine/5ylv) | Crystal structure of the gastric proton pump complexed with SCH28080 | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-(2-methyl-8-phenylmethoxy-imidazo[1,2-a]pyridin-3-yl)ethanenitrile, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Abe, K, Irie, K, Nakanishi, H, Fujiyoshi, Y. | 登録日 | 2017-10-19 | 公開日 | 2018-04-11 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.79977775 Å) | 主引用文献 | Crystal structures of the gastric proton pump Nature, 556, 2018
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5Y0B
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![BU of 5y0b by Molmil](/molmil-images/mine/5y0b) | PIG GASTRIC H+,K+ - ATPASE IN COMPLEX with BYK99 | 分子名称: | Potassium-transporting ATPase alpha chain 1, Potassium-transporting ATPase subunit beta | 著者 | Abe, K, Shimokawa, J, Natio, M, Munson, K, Vagin, O, Sachs, G, Suzuki, H, Tani, K, Fujiyoshi, Y. | 登録日 | 2017-07-16 | 公開日 | 2017-08-09 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (6.7 Å) | 主引用文献 | The cryo-EM structure of gastric H(+),K(+)-ATPase with bound BYK99, a high-affinity member of K(+)-competitive, imidazo[1,2-a]pyridine inhibitors Sci Rep, 7, 2017
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5YLU
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![BU of 5ylu by Molmil](/molmil-images/mine/5ylu) | Crystal structure of the gastric proton pump complexed with vonoprazan | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1-[5-(2-fluorophenyl)-1-pyridin-3-ylsulfonyl-pyrrol-3-yl]-~{N}-methyl-methanamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Abe, K, Irie, K, Nakanishi, H, Fujiyoshi, Y. | 登録日 | 2017-10-19 | 公開日 | 2018-04-11 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.79988956 Å) | 主引用文献 | Crystal structures of the gastric proton pump Nature, 556, 2018
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5XA8
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![BU of 5xa8 by Molmil](/molmil-images/mine/5xa8) | Complete structure factors and an atomic model of the calcium pump (SERCA1A) and associated phospholipids in the E1-ALF4-ADP-2CA2+ crystals | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, ... | 著者 | Norimatsu, Y, Hasegawa, K, Shimizu, N, Toyoshima, C. | 登録日 | 2017-03-11 | 公開日 | 2017-05-17 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Protein-phospholipid interplay revealed with crystals of a calcium pump. Nature, 545, 2017
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5XAA
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![BU of 5xaa by Molmil](/molmil-images/mine/5xaa) | Complete structure factors and an atomic model of the calcium pump (SERCA1A) and associated phospholipids in the E2-ALF-(TG) crystals of P21212 symmetry | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, MAGNESIUM ION, OCTANOIC ACID [3S-[3ALPHA, ... | 著者 | Norimatsu, Y, Hasegawa, K, Shimizu, N, Toyoshima, C. | 登録日 | 2017-03-11 | 公開日 | 2017-05-24 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Protein-phospholipid interplay revealed with crystals of a calcium pump. Nature, 545, 2017
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5ZMV
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![BU of 5zmv by Molmil](/molmil-images/mine/5zmv) | Crystal structure of the E309A mutant of SR Ca2+-ATPase in E2(TG) | 分子名称: | OCTANOIC ACID [3S-[3ALPHA, 3ABETA, 4ALPHA, ... | 著者 | Ogawa, H, Hirata, A, Tsueda, J, Toyoshima, C. | 登録日 | 2018-04-06 | 公開日 | 2018-12-12 | 最終更新日 | 2018-12-26 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Mechanism of the E2 to E1 transition in Ca2+pump revealed by crystal structures of gating residue mutants. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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2DQS
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![BU of 2dqs by Molmil](/molmil-images/mine/2dqs) | |
2BY4
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![BU of 2by4 by Molmil](/molmil-images/mine/2by4) | SR Ca(2+)-ATPase in the HnE2 state complexed with the thapsigargin derivative Boc-12ADT. | 分子名称: | (3S,3AR,4S,6S,6AR,7S,8S,9BS)-6-(ACETYLOXY)-3,3A-DIHYDROXY-3,6,9-TRIMETHYL-8-{[(2Z)-2-METHYLBUT-2-ENOYL]OXY}-7-(OCTANOYLOXY)-2-OXO-2,3,3A,4,5,6,6A,7,8,9B-DECAHYDROAZULENO[4,5-B]FURAN-4-YL 12-[(TERT-BUTOXYCARBONYL)AMINO]DODECANOATE, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... | 著者 | Jensen, A.L, Moller, J.V, Soehoel, H, Denmeade, S.R, Isaacs, J.T, Olsen, C.E, Christensen, S.B, Nissen, P. | 登録日 | 2005-07-28 | 公開日 | 2006-04-07 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Natural Products as Starting Materials for Development of Second-Generation Serca Inhibitors Targeted Towards Prostate Cancer Cells Bioorg.Med.Chem., 14, 2006
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2C88
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![BU of 2c88 by Molmil](/molmil-images/mine/2c88) | Crystal Structure Of (SR) Calcium-ATPase E2(Tg):AMPPCP form | 分子名称: | MAGNESIUM ION, OCTANOIC ACID [3S-[3ALPHA, 3ABETA, ... | 著者 | Jensen, A.M, Sorensen, T.L, Olesen, C, Moller, J.V, Nissen, P. | 登録日 | 2005-12-02 | 公開日 | 2006-06-13 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Modulatory and Catalytic Modes of ATP Binding by the Calcium Pump Embo J., 25, 2006
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2C8L
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![BU of 2c8l by Molmil](/molmil-images/mine/2c8l) | Crystal Structure of (SR) Calcium-ATPase E2(Tg) form | 分子名称: | OCTANOIC ACID [3S-[3ALPHA, 3ABETA, 4ALPHA, ... | 著者 | Jensen, A.M, Sorensen, T.L, Olesen, C, Moller, J.V, Nissen, P. | 登録日 | 2005-12-06 | 公開日 | 2006-06-13 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Modulatory and Catalytic Modes of ATP Binding by the Calcium Pump Embo J., 25, 2006
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2C8K
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![BU of 2c8k by Molmil](/molmil-images/mine/2c8k) | Crystal Structure of (SR) Calcium-ATPase E2(Tg) with partially occupied AMPPCP site | 分子名称: | ARCOPLASMIC/ENDOPLASMIC RETICULUM CALCIUM ATPASE 1, MAGNESIUM ION, OCTANOIC ACID [3S-[3ALPHA, ... | 著者 | Jensen, A.M, Sorensen, T.L, Olesen, C, Moller, J.V, Nissen, P. | 登録日 | 2005-12-06 | 公開日 | 2006-06-13 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Modulatory and Catalytic Modes of ATP Binding by the Calcium Pump Embo J., 25, 2006
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2AGV
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![BU of 2agv by Molmil](/molmil-images/mine/2agv) | Crystal structure of the SR CA2+-ATPASE with BHQ and TG | 分子名称: | 2,5-DITERT-BUTYLBENZENE-1,4-DIOL, OCTANOIC ACID [3S-[3ALPHA, 3ABETA, ... | 著者 | Toyoshima, C, Obara, K, Norimatsu, Y. | 登録日 | 2005-07-27 | 公開日 | 2005-10-25 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Inaugural Article: Structural role of countertransport revealed in Ca2+ pump crystal structure in the absence of Ca2+. Proc.Natl.Acad.Sci.USA, 102, 2005
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2C9M
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![BU of 2c9m by Molmil](/molmil-images/mine/2c9m) | Structure of (SR) Calcium-ATPase in the Ca2E1 state solved in a P1 crystal form. | 分子名称: | CALCIUM ION, CHLORIDE ION, POTASSIUM ION, ... | 著者 | Lund Jensen, A.-M, Sorensen, T.L.-M, Olesen, C, Moller, J.V, Nissen, P. | 登録日 | 2005-12-13 | 公開日 | 2006-12-18 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Modulatory and Catalytic Modes of ATP Binding by the Calcium Pump Embo J., 25, 2006
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2EAU
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![BU of 2eau by Molmil](/molmil-images/mine/2eau) | Crystal structure of the SR CA2+-ATPASE with bound CPA in the presence of curcumin | 分子名称: | (6AR,11AS,11BR)-10-ACETYL-9-HYDROXY-7,7-DIMETHYL-2,6,6A,7,11A,11B-HEXAHYDRO-11H-PYRROLO[1',2':2,3]ISOINDOLO[4,5,6-CD]INDOL-11-ONE, PHOSPHATIDYLETHANOLAMINE, Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 著者 | Takahashi, M, Kondou, Y, Toyoshima, C. | 登録日 | 2007-02-02 | 公開日 | 2007-03-27 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Interdomain communication in calcium pump as revealed in the crystal structures with transmembrane inhibitors Proc.Natl.Acad.Sci.Usa, 104, 2007
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2EAR
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![BU of 2ear by Molmil](/molmil-images/mine/2ear) | P21 crystal of the SR CA2+-ATPase with bound TG | 分子名称: | OCTANOIC ACID [3S-[3ALPHA, 3ABETA, 4ALPHA, ... | 著者 | Takahashi, M, Kondou, Y, Toyoshima, C. | 登録日 | 2007-02-02 | 公開日 | 2007-03-27 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Interdomain communication in calcium pump as revealed in the crystal structures with transmembrane inhibitors Proc.Natl.Acad.Sci.Usa, 104, 2007
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2EAT
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![BU of 2eat by Molmil](/molmil-images/mine/2eat) | Crystal structure of the SR CA2+-ATPASE with bound CPA and TG | 分子名称: | (6AR,11AS,11BR)-10-ACETYL-9-HYDROXY-7,7-DIMETHYL-2,6,6A,7,11A,11B-HEXAHYDRO-11H-PYRROLO[1',2':2,3]ISOINDOLO[4,5,6-CD]INDOL-11-ONE, OCTANOIC ACID [3S-[3ALPHA, 3ABETA, ... | 著者 | Takahashi, M, Kondou, Y, Toyoshima, C. | 登録日 | 2007-02-02 | 公開日 | 2007-03-27 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Interdomain communication in calcium pump as revealed in the crystal structures with transmembrane inhibitors Proc.Natl.Acad.Sci.Usa, 104, 2007
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8IJM
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![BU of 8ijm by Molmil](/molmil-images/mine/8ijm) | Cyo-EM structure of K794A non-gastric proton pump in Na+ bound E1AMPPCP state | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ... | 著者 | Abe, K. | 登録日 | 2023-02-27 | 公開日 | 2023-08-02 | 最終更新日 | 2023-08-09 | 実験手法 | ELECTRON MICROSCOPY (3.13 Å) | 主引用文献 | An unusual conformation from Na + -sensitive non-gastric proton pump mutants reveals molecular mechanisms of cooperative Na + -binding. Biochim Biophys Acta Mol Cell Res, 1870, 2023
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8IJX
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![BU of 8ijx by Molmil](/molmil-images/mine/8ijx) | Cryo-EM structure of the gastric proton pump with bound DQ-18 | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1-[4-[(5-chloranyl-2-phenylmethoxy-phenyl)methoxy]phenyl]-N-methyl-methanamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Abe, K, Yokoshima, S, Yoshimori, A. | 登録日 | 2023-02-28 | 公開日 | 2023-08-30 | 最終更新日 | 2023-10-04 | 実験手法 | ELECTRON MICROSCOPY (2.08 Å) | 主引用文献 | Deep learning driven de novo drug design based on gastric proton pump structures. Commun Biol, 6, 2023
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8IJW
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![BU of 8ijw by Molmil](/molmil-images/mine/8ijw) | Cryo-EM structure of the gastric proton pump with bound DQ-06 | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ... | 著者 | Abe, K, Yokoshima, S, Yoshimori, A. | 登録日 | 2023-02-28 | 公開日 | 2023-08-30 | 最終更新日 | 2023-10-04 | 実験手法 | ELECTRON MICROSCOPY (2.19 Å) | 主引用文献 | Deep learning driven de novo drug design based on gastric proton pump structures. Commun Biol, 6, 2023
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