5XAB

Complete structure factors and an atomic model of the calcium pump (SERCA1A) and associated phospholipids in the E2(TG) crystals

Summary for 5XAB

• Entry DOI: 10.2210/pdb5xab/pdb
• Related: 5XA7 5XA8 5XA9 5XAA
• Descriptor: Sarcoplasmic/endoplasmic reticulum calcium ATPase 1, SODIUM ION, OCTANOIC ACID [3S-[3ALPHA, 3ABETA, 4ALPHA, 6BETA, 6ABETA, 7BETA, 8ALPHA(Z), 9BALPHA]]-6-(ACETYLOXY)-2,3,-3A,4,5,6,6A,7,8,9B-DECAHYDRO-3,3A-DIHYDROXY-3,6,9-TRIMETHYL-8-[(2-METHYL-1-OXO-2-BUTENYL)OX Y]-2-OXO-4-(1-OXOBUTOXY)-AZULENO[4,5-B]FURAN-7-YL ESTER, ... (5 entities in total)
• Functional Keywords: p-type atpase, hydrolase, calcium transport, calcium binding, atp binding, endoplasmic reticulum, sarcoplasmic reticulum, metal transport
• Biological source: Oryctolagus cuniculus (Rabbit)
• Cellular location: Endoplasmic reticulum membrane ; Multi-pass membrane protein : P04191
• Total number of polymer chains: 1
• Total formula weight: 133915.99

Authors

Norimatsu, Y.,Hasegawa, K.,Shimizu, N.,Toyoshima, C. (deposition date: 2017-03-11, release date: 2017-06-07, Last modification date: 2023-11-22)

• Primary citation: Norimatsu, Y.,Hasegawa, K.,Shimizu, N.,Toyoshima, C.; Protein-phospholipid interplay revealed with crystals of a calcium pump.; Nature, 545:193-198, 2017; PubMed: 28467821; DOI: 10.1038/nature22357

Experimental method

X-RAY DIFFRACTION (3.2 Å)