2AGV
Crystal structure of the SR CA2+-ATPASE with BHQ and TG
Summary for 2AGV
Entry DOI | 10.2210/pdb2agv/pdb |
Related | 1IWO 1SU4 1VFP 1WPE 1WPG |
Descriptor | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1, SODIUM ION, OCTANOIC ACID [3S-[3ALPHA, 3ABETA, 4ALPHA, 6BETA, 6ABETA, 7BETA, 8ALPHA(Z), 9BALPHA]]-6-(ACETYLOXY)-2,3,-3A,4,5,6,6A,7,8,9B-DECAHYDRO-3,3A-DIHYDROXY-3,6,9-TRIMETHYL-8-[(2-METHYL-1-OXO-2-BUTENYL)OX Y]-2-OXO-4-(1-OXOBUTOXY)-AZULENO[4,5-B]FURAN-7-YL ESTER, ... (6 entities in total) |
Functional Keywords | membrane protein, p-type atpase, had fold, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Oryctolagus cuniculus (rabbit) |
Cellular location | Endoplasmic reticulum membrane; Multi-pass membrane protein: P04191 |
Total number of polymer chains | 2 |
Total formula weight | 225401.52 |
Authors | Toyoshima, C.,Obara, K.,Norimatsu, Y. (deposition date: 2005-07-27, release date: 2005-10-25, Last modification date: 2023-10-25) |
Primary citation | Obara, K.,Miyashita, N.,Xu, C.,Toyoshima, I.,Sugita, Y.,Inesi, G.,Toyoshima, C. Inaugural Article: Structural role of countertransport revealed in Ca2+ pump crystal structure in the absence of Ca2+. Proc.Natl.Acad.Sci.USA, 102:14489-14496, 2005 Cited by PubMed: 16150713DOI: 10.1073/pnas.0506222102 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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