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PDB: 102 件

2R9H
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BU of 2r9h by Molmil
Crystal Structure of Q207C Mutant of CLC-ec1 in complex with Fab
分子名称: CHLORIDE ION, Fab fragment, H(+)/Cl(-) exchange transporter clcA
著者Nguitragool, W, Miller, C.
登録日2007-09-12
公開日2007-11-20
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crystal Structure of Q207C Mutant of CLC-ec1 in complex with Fab
To be Published
6V2J
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BU of 6v2j by Molmil
Crystal structure of ClC-ec1 triple mutant (E113Q, E148Q, E203Q)
分子名称: CHLORIDE ION, H(+)/Cl(-) exchange transporter ClcA
著者Maduke, M, Mathews, I.I, Chavan, T.S.
登録日2019-11-24
公開日2020-05-20
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献A CLC-ec1 mutant reveals global conformational change and suggests a unifying mechanism for the CLC Cl - /H + transport cycle.
Elife, 9, 2020
6LSC
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BU of 6lsc by Molmil
Structure of the E202Y mutant of the Cl-/H+ antiporter CLC-ec1 from E.coli: a re-refined model of the 4FTP model
分子名称: CHLORIDE ION, H(+)/Cl(-) exchange transporter ClcA
著者Lim, H.H, Shane, T, Miller, C.
登録日2020-01-17
公開日2020-02-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.21 Å)
主引用文献Intracellular proton access in a Cl(-)/H(+) antiporter.
PLoS Biol., 10, 2012
3Q17
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Structure of a slow CLC Cl-/H+ antiporter from a cyanobacterium in Bromide
分子名称: BROMIDE ION, Sll0855 protein
著者Jayaram, H, Robertson, J.L, Fang, W, Williams, C, Miller, C.
登録日2010-12-16
公開日2011-01-19
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Structure of a Slow CLC Cl(-)/H(+) Antiporter from a Cyanobacterium.
Biochemistry, 50, 2011
5HD8
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BU of 5hd8 by Molmil
Crystal structure of disulfide cross-linked D417C ClC-ec1
分子名称: CHLORIDE ION, FAB FRAGMENT (HEAVY CHAIN), FAB FRAGMENT (LIGHT CHAIN), ...
著者Mathews, I.I, Khantwal, C.M, Maduke, M.
登録日2016-01-05
公開日2017-01-18
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Conformational change in CLC transporters: beyond the rotation of Gluex
To be published
2FEE
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BU of 2fee by Molmil
Structure of the Cl-/H+ exchanger CLC-ec1 from E.Coli in NaBr
分子名称: Fab fragment, heavy chain, light chain, ...
著者Accardi, A, Walden, M.P, Nguitragool, W, Jayaram, H, Williams, C, Miller, C.
登録日2005-12-15
公開日2006-01-03
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Separate ion pathways in a Cl-/H+ exchanger
J.Gen.Physiol., 126, 2005
2FED
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BU of 2fed by Molmil
Structure of the E203Q mutant of the Cl-/H+ exchanger CLC-ec1 from E.Coli
分子名称: Fab fragment, heavy chain, light chain, ...
著者Accardi, A, Walden, M.P, Nguitragool, W, Jayaram, H, Williams, C, Miller, C.
登録日2005-12-15
公開日2006-01-03
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.317 Å)
主引用文献Separate ion pathways in a Cl-/H+ exchanger
J.Gen.Physiol., 126, 2005
4ENE
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BU of 4ene by Molmil
Structure of the N- and C-terminal trimmed ClC-ec1 Cl-/H+ antiporter and Fab Complex
分子名称: CHLORIDE ION, DECYL-BETA-D-MALTOPYRANOSIDE, H(+)/Cl(-) exchange transporter ClcA, ...
著者Lim, H.H, Shane, T, Miller, C.
登録日2012-04-13
公開日2012-12-26
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Intracellular proton access in a cl(-)/h(+) antiporter.
Plos Biol., 10, 2012
4FG6
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BU of 4fg6 by Molmil
Structure of EcCLC E148A mutant in Glutamate
分子名称: Fab fragment (Heavy chain), Fab fragment (Light chain), H(+)/Cl(-) exchange transporter ClcA
著者Feng, L, MacKinnon, R.
登録日2012-06-04
公開日2012-07-04
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.019 Å)
主引用文献Molecular mechanism of proton transport in CLC Cl-/H+ exchange transporters.
Proc.Natl.Acad.Sci.USA, 109, 2012
5TR1
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BU of 5tr1 by Molmil
Cryo-electron microscopy structure of a bovine CLC-K chloride channel, alternate (class 2) conformation
分子名称: CHOLESTEROL HEMISUCCINATE, Chloride channel protein, Monoclonal antibody, ...
著者Park, E, MacKinnon, R.
登録日2016-10-25
公開日2017-01-11
最終更新日2019-11-20
実験手法ELECTRON MICROSCOPY (3.95 Å)
主引用文献Structure of a CLC chloride ion channel by cryo-electron microscopy.
Nature, 541, 2017
7N8P
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CLC-ec1 at pH 4.5 100mM Cl Swap
分子名称: H(+)/Cl(-) exchange transporter ClcA
著者Fortea, E, Boudker, O, Accardi, A.
登録日2021-06-15
公開日2022-11-16
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.42 Å)
主引用文献Structural basis of common gate activation in CLC transporters
To Be Published
7N9W
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BU of 7n9w by Molmil
CLC-ec1 pH 4.5 100mM Cl Twist1
分子名称: H(+)/Cl(-) exchange transporter ClcA
著者Fortea, E, Boudker, O, Accardi, A.
登録日2021-06-18
公開日2022-11-16
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (4.16 Å)
主引用文献Structural basis of common gate activation in CLC transporters
To Be Published
1KPK
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BU of 1kpk by Molmil
Crystal Structure of the ClC Chloride Channel from E. coli
分子名称: putative channel transporter
著者Dutzler, R, Campbell, E.B, Cadene, M, Chait, B.T, MacKinnon, R.
登録日2001-12-31
公開日2002-01-23
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献X-ray structure of a ClC chloride channel at 3.0 A reveals the molecular basis of anion selectivity.
Nature, 415, 2002
1KPL
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BU of 1kpl by Molmil
Crystal Structure of the ClC Chloride Channel from S. typhimurium
分子名称: CHLORIDE ION, N-OCTANE, PENTADECANE, ...
著者Dutzler, R, Campbell, E.B, Cadene, M, Chait, B.T, MacKinnon, R.
登録日2001-12-31
公開日2002-01-23
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献X-ray structure of a ClC chloride channel at 3.0 A reveals the molecular basis of anion selectivity.
Nature, 415, 2002
3NMO
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BU of 3nmo by Molmil
Crystal structure of an engineered monomeric CLC-ec1 Cl-/H+ transporter
分子名称: CHLORIDE ION, H(+)/Cl(-) exchange transporter clcA
著者Robertson, J.L, Kolmakova-Partensky, L, Miller, C.
登録日2010-06-22
公開日2010-07-21
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Design, function and structure of a monomeric ClC transporter.
Nature, 468, 2010
5TQQ
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BU of 5tqq by Molmil
Cryo-electron microscopy structure of a bovine CLC-K chloride channel, main (class 1) conformation
分子名称: Chloride channel protein, Monoclonal antibody, Fab fragment, ...
著者Park, E, MacKinnon, R.
登録日2016-10-24
公開日2017-01-04
最終更新日2019-11-20
実験手法ELECTRON MICROSCOPY (3.76 Å)
主引用文献Structure of a CLC chloride ion channel by cryo-electron microscopy.
Nature, 541, 2017
6K5F
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BU of 6k5f by Molmil
Crystal structure of the CLC-ec1 deltaNC in presence of 200 mM NaBr
分子名称: BROMIDE ION, Fab fragment, heavy chain, ...
著者Park, K, Lim, H.H.
登録日2019-05-28
公開日2019-08-28
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.203 Å)
主引用文献Mutation of external glutamate residue reveals a new intermediate transport state and anion binding site in a CLC Cl-/H+antiporter.
Proc.Natl.Acad.Sci.USA, 116, 2019
3ND0
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BU of 3nd0 by Molmil
X-ray crystal structure of a slow cyanobacterial Cl-/H+ antiporter
分子名称: CHLORIDE ION, Sll0855 protein
著者Jayaram, H, Robertson, J, Wu, F, Williams, C, Miller, C.
登録日2010-06-06
公開日2011-01-19
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structure of a Slow CLC Cl(-)/H(+) Antiporter from a Cyanobacterium.
Biochemistry, 50, 2011
6K5D
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BU of 6k5d by Molmil
Crystal structure of the E148N mutant CLC-ec1 in presence of 200 mM NaBr
分子名称: BROMIDE ION, Fab fragment, heavy chain, ...
著者Park, K, Lim, H.H.
登録日2019-05-28
公開日2019-08-28
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.203 Å)
主引用文献Mutation of external glutamate residue reveals a new intermediate transport state and anion binding site in a CLC Cl-/H+antiporter.
Proc.Natl.Acad.Sci.USA, 116, 2019
7XJA
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BU of 7xja by Molmil
TMD masked refine map of human ClC-2
分子名称: Chloride channel protein 2
著者Wang, L.
登録日2022-04-15
公開日2023-05-17
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Cryo-EM structures of ClC-2 chloride channel reveal the blocking mechanism of its specific inhibitor AK-42
Nat Commun, 14, 2023
7XF5
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BU of 7xf5 by Molmil
Full length human CLC-2 channel in apo state
分子名称: Chloride channel protein 2
著者Wang, L.
登録日2022-04-01
公開日2023-05-03
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Cryo-EM structures of ClC-2 chloride channel reveal the blocking mechanism of its specific inhibitor AK-42
Nat Commun, 14, 2023
3EJY
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BU of 3ejy by Molmil
Structure of E203H mutant of E.coli Cl-/H+ antiporter, CLC-ec1
分子名称: BROMIDE ION, Fab fragment, Heavy chain, ...
著者Lim, H.-H, Miller, C.
登録日2008-09-18
公開日2009-02-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Intracellular proton-transfer mutants in a CLC Cl-/H+ exchanger.
J.Gen.Physiol., 133, 2009
3DET
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BU of 3det by Molmil
Structure of the E148A, Y445A doubly ungated mutant of E.coli CLC_Ec1, Cl-/H+ antiporter
分子名称: Fab fragment, Heavy chain, Light chain, ...
著者Jayaram, H, Accardi, A, Wu, F, Williams, C, Miller, C.
登録日2008-06-10
公開日2008-06-17
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Ion permeation through a Cl--selective channel designed from a CLC Cl-/H+ exchanger
Proc.Natl.Acad.Sci.USA, 105, 2008
2FEC
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BU of 2fec by Molmil
Structure of the E203Q mutant of the Cl-/H+ exchanger CLC-ec1 from E.Coli
分子名称: Fab fragment, heavy chain, light chain, ...
著者Accardi, A, Walden, M.P, Nguitragool, W, Jayaram, H, Williams, C, Miller, C.
登録日2005-12-15
公開日2006-01-03
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (3.967 Å)
主引用文献Separate ion pathways in a Cl-/H+ exchanger
J.Gen.Physiol., 126, 2005
2EXW
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BU of 2exw by Molmil
Crystal structure of a EcClC-Fab complex in the absence of bound ions
分子名称: Fab Fragment (Heavy Chain), Fab Fragment (Light Chain), H(+)/Cl(-) exchange transporter clcA
著者Lobet, S, Dutzler, R.
登録日2005-11-09
公開日2006-01-24
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Ion-binding properties of the ClC chloride selectivity filter.
Embo J., 25, 2006

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