5ZAK
 
 | | Cryo-EM structure of human Dicer and its complexes with a pre-miRNA substrate | | 分子名称: | Endoribonuclease Dicer, RISC-loading complex subunit TARBP2 | | 著者 | Liu, Z, Wang, J, Cheng, H, Ke, X, Sun, L, Zhang, Q.C, Wang, H.-W. | | 登録日 | 2018-02-07 | | 公開日 | 2018-05-09 | | 最終更新日 | 2019-11-06 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | Cryo-EM Structure of Human Dicer and Its Complexes with a Pre-miRNA Substrate.
Cell, 173, 2018
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6BUA
 | | Drosophila Dicer-2 apo homology model (helicase, Platform-PAZ, RNaseIII domains) | | 分子名称: | Dicer-2, isoform A | | 著者 | Shen, P.S, Sinha, N.K, Bass, B.L. | | 登録日 | 2017-12-09 | | 公開日 | 2017-12-27 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (7.1 Å) | | 主引用文献 | Dicer uses distinct modules for recognizing dsRNA termini.
Science, 359, 2018
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6BU9
 | | Drosophila Dicer-2 bound to blunt dsRNA | | 分子名称: | Dicer-2, isoform A, RNA (5'-R(*AP*CP*UP*AP*CP*UP*AP*UP*AP*CP*AP*AP*CP*CP*UP*AP*C)-3'), ... | | 著者 | Shen, P.S, Sinha, N.K, Bass, B.L. | | 登録日 | 2017-12-09 | | 公開日 | 2017-12-27 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (6.8 Å) | | 主引用文献 | Dicer uses distinct modules for recognizing dsRNA termini.
Science, 359, 2018
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8DGA
 | | Structural Basis of MicroRNA Biogenesis by Dicer-1 and Its Partner Protein Loqs-PB - complex IV | | 分子名称: | Endoribonuclease Dcr-1, Loquacious, isoform B, ... | | 著者 | Jouravleva, K, Golovenko, D, Demo, G, Dutcher, R.C, Tanaka Hall, T.M, Zamore, P.D, Korostelev, A.A. | | 登録日 | 2022-06-23 | | 公開日 | 2022-11-16 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.73 Å) | | 主引用文献 | Structural basis of microRNA biogenesis by Dicer-1 and its partner protein Loqs-PB.
Mol.Cell, 82, 2022
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8DFV
 | | Structural Basis of MicroRNA Biogenesis by Dicer-1 and Its Partner Protein Loqs-PB - complex IIa | | 分子名称: | CALCIUM ION, Endoribonuclease Dcr-1, Loquacious, ... | | 著者 | Jouravleva, K, Golovenko, D, Demo, G, Dutcher, R.C, Tanaka Hall, T.M, Zamore, P.D, Korostelev, A.A. | | 登録日 | 2022-06-22 | | 公開日 | 2022-11-16 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.06 Å) | | 主引用文献 | Structural basis of microRNA biogenesis by Dicer-1 and its partner protein Loqs-PB.
Mol.Cell, 82, 2022
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8DG7
 | | Structural Basis of MicroRNA Biogenesis by Dicer-1 and Its Partner Protein Loqs-PB - complex III | | 分子名称: | Endoribonuclease Dcr-1, Loquacious, isoform B, ... | | 著者 | Jouravleva, K, Golovenko, D, Demo, G, Dutcher, R.C, Tanaka Hall, T.M, Zamore, P.D, Korostelev, A.A. | | 登録日 | 2022-06-23 | | 公開日 | 2022-11-16 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.32 Å) | | 主引用文献 | Structural basis of microRNA biogenesis by Dicer-1 and its partner protein Loqs-PB.
Mol.Cell, 82, 2022
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8DGJ
 | | Structural Basis of MicroRNA Biogenesis by Dicer-1 and Its Partner Protein Loqs-PB - complex Ib | | 分子名称: | Endoribonuclease Dcr-1, Loquacious, isoform B | | 著者 | Jouravleva, K, Golovenko, D, Demo, G, Dutcher, R.C, Tanaka Hall, T.M, Zamore, P.D, Korostelev, A.A. | | 登録日 | 2022-06-23 | | 公開日 | 2022-11-16 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (4.02 Å) | | 主引用文献 | Structural basis of microRNA biogenesis by Dicer-1 and its partner protein Loqs-PB.
Mol.Cell, 82, 2022
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8DGI
 | | Structural Basis of MicroRNA Biogenesis by Dicer-1 and Its Partner Protein Loqs-PB - complex Ia | | 分子名称: | Endoribonuclease Dcr-1, Loquacious, isoform B | | 著者 | Jouravleva, K, Golovenko, D, Demo, G, Dutcher, R.C, Tanaka Hall, T.M, Zamore, P.D, Korostelev, A.A. | | 登録日 | 2022-06-23 | | 公開日 | 2022-11-16 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.94 Å) | | 主引用文献 | Structural basis of microRNA biogenesis by Dicer-1 and its partner protein Loqs-PB.
Mol.Cell, 82, 2022
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8DG5
 | | Structural Basis of MicroRNA Biogenesis by Dicer-1 and Its Partner Protein Loqs-PB - complex IIb | | 分子名称: | Endoribonuclease Dcr-1, Loquacious, isoform B, ... | | 著者 | Jouravleva, K, Golovenko, D, Demo, G, Dutcher, R.C, Tanaka Hall, T.M, Zamore, P.D, Korostelev, A.A. | | 登録日 | 2022-06-23 | | 公開日 | 2022-11-16 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.26 Å) | | 主引用文献 | Structural basis of microRNA biogenesis by Dicer-1 and its partner protein Loqs-PB.
Mol.Cell, 82, 2022
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7YZ4
 | | Mouse endoribonuclease Dicer (composite structure) | | 分子名称: | Endoribonuclease Dicer | | 著者 | Zanova, M, Zapletal, D, Kubicek, K, Stefl, R, Pinkas, M, Novacek, J. | | 登録日 | 2022-02-18 | | 公開日 | 2022-11-16 | | 実験手法 | ELECTRON MICROSCOPY (3.84 Å) | | 主引用文献 | Structural and functional basis of mammalian microRNA biogenesis by Dicer.
Mol.Cell, 82, 2022
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7W0D
 | | Dicer2-LoqsPD-dsRNA complex at mid-translocation state | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Dicer-2, isoform A, ... | | 著者 | Su, S, Wang, J, Wang, H.W, Ma, J. | | 登録日 | 2021-11-18 | | 公開日 | 2022-04-27 | | 最終更新日 | 2022-07-27 | | 実験手法 | ELECTRON MICROSCOPY (4.18 Å) | | 主引用文献 | Structural insights into dsRNA processing by Drosophila Dicer-2-Loqs-PD.
Nature, 607, 2022
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7W0B
 | | Dicer2-LoqsPD complex at apo status | | 分子名称: | Dicer-2, isoform A, Loquacious, ... | | 著者 | Su, S, Wang, J, Wang, H.W, Ma, J. | | 登録日 | 2021-11-18 | | 公開日 | 2022-04-27 | | 最終更新日 | 2022-07-27 | | 実験手法 | ELECTRON MICROSCOPY (3.33 Å) | | 主引用文献 | Structural insights into dsRNA processing by Drosophila Dicer-2-Loqs-PD.
Nature, 607, 2022
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7W0E
 | | dmDicer2-LoqsPD-dsRNA Active-dicing status | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Dicer-2, isoform A, ... | | 著者 | Su, S, Wang, J, Wang, H.W, Ma, J. | | 登録日 | 2021-11-18 | | 公開日 | 2022-04-27 | | 最終更新日 | 2022-07-27 | | 実験手法 | ELECTRON MICROSCOPY (4.03 Å) | | 主引用文献 | Structural insights into dsRNA processing by Drosophila Dicer-2-Loqs-PD.
Nature, 607, 2022
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7W0F
 | | dmDicer2-LoqsPD-dsRNA Post-dicing status | | 分子名称: | Dicer-2, isoform A, Loquacious, ... | | 著者 | Su, S, Wang, J, Wang, H.W, Ma, J. | | 登録日 | 2021-11-18 | | 公開日 | 2022-04-27 | | 最終更新日 | 2022-07-27 | | 実験手法 | ELECTRON MICROSCOPY (4.55 Å) | | 主引用文献 | Structural insights into dsRNA processing by Drosophila Dicer-2-Loqs-PD.
Nature, 607, 2022
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7W0A
 | | dmDicer2-LoqsPD-dsRNA Dimer status | | 分子名称: | Dicer-2, isoform A, Loquacious, ... | | 著者 | Su, S, Wang, J, Wang, H.W, Ma, J. | | 登録日 | 2021-11-18 | | 公開日 | 2022-04-27 | | 最終更新日 | 2022-07-27 | | 実験手法 | ELECTRON MICROSCOPY (3.12 Å) | | 主引用文献 | Structural insights into dsRNA processing by Drosophila Dicer-2-Loqs-PD.
Nature, 607, 2022
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7W0C
 | | Dicer2-Loqs-PD-dsRNA complex at early-translocation state | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Dicer-2, isoform A, ... | | 著者 | Su, S, Wang, J, Wang, H.W, Ma, J. | | 登録日 | 2021-11-18 | | 公開日 | 2022-04-27 | | 最終更新日 | 2022-07-27 | | 実験手法 | ELECTRON MICROSCOPY (3.93 Å) | | 主引用文献 | Structural insights into dsRNA processing by Drosophila Dicer-2-Loqs-PD.
Nature, 607, 2022
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7YYM
 | | Mammalian Dicer in the "pre-dicing state" with pre-miR-15a substrate | | 分子名称: | 59-nt precursor of miR-15a, Endoribonuclease Dicer | | 著者 | Zanova, M, Zapletal, D, Kubicek, K, Stefl, R, Pinkas, M, Novacek, J. | | 登録日 | 2022-02-18 | | 公開日 | 2022-11-16 | | 実験手法 | ELECTRON MICROSCOPY (4.19 Å) | | 主引用文献 | Structural and functional basis of mammalian microRNA biogenesis by Dicer.
Mol.Cell, 82, 2022
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7YYN
 | | Mammalian Dicer in the dicing state with pre-miR-15a substrate | | 分子名称: | 59-nt precursor of miR-15a, Isoform 2 of Endoribonuclease Dicer | | 著者 | Zanova, M, Zapletal, D, Kubicek, K, Stefl, R, Pinkas, M, Novacek, J. | | 登録日 | 2022-02-18 | | 公開日 | 2022-11-16 | | 実験手法 | ELECTRON MICROSCOPY (6.21 Å) | | 主引用文献 | Structural and functional basis of mammalian microRNA biogenesis by Dicer.
Mol.Cell, 82, 2022
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7XW3
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7XW2
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