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PDB: 292 件

3FEY
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Crystal structure of the CBC-importin alpha complex.
分子名称: Importin subunit alpha-2, Nuclear cap-binding protein subunit 1, Nuclear cap-binding protein subunit 2
著者Dias, S.M.G, Ambrosio, A.L.B, Cerione, R.A.
登録日2008-12-01
公開日2009-08-11
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The molecular basis for the regulation of the cap-binding complex by the importins.
Nat.Struct.Mol.Biol., 16, 2009
3FEX
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BU of 3fex by Molmil
Crystal structure of the CBC-importin alpha complex.
分子名称: Importin subunit alpha-2, Nuclear cap-binding protein subunit 1, Nuclear cap-binding protein subunit 2
著者Dias, S.M.G, Ambrosio, A.L.B, Cerione, R.A.
登録日2008-12-01
公開日2009-08-11
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.549 Å)
主引用文献The molecular basis for the regulation of the cap-binding complex by the importins.
Nat.Struct.Mol.Biol., 16, 2009
8J07
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96nm repeat of human respiratory doublet microtubule and associated axonemal complexes
分子名称: ACTA2, Axonemal dynein light intermediate polypeptide 1, Calaxin, ...
著者Gui, M, Brown, A.
登録日2023-04-09
公開日2023-07-26
最終更新日2023-08-02
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Axonemal structures reveal mechanoregulatory and disease mechanisms.
Nature, 618, 2023
1WA5
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Structure of the Cse1:Imp-alpha:RanGTP complex
分子名称: GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, Importin alpha re-exporter, ...
著者Stewart, M.
登録日2004-10-23
公開日2004-12-13
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for the assembly of a nuclear export complex.
Nature, 432, 2004
6WX7
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SOX2 bound to Importin-alpha 2
分子名称: Importin subunit alpha-1, Transcription factor SOX-2
著者Bikshapathi, J, Stewart, M, Forwood, J.K, Aragao, D, Roman, N.
登録日2020-05-09
公開日2020-10-28
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural basis for nuclear import selectivity of pioneer transcription factor SOX2.
Nat Commun, 12, 2021
6WX8
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SOX2 bound to Importin-alpha 3
分子名称: Importin subunit alpha-3, SULFATE ION, Transcription factor SOX-2
著者Bikshapathi, J, Stewart, M, Forwood, J.K, Aragao, D, Roman, N.
登録日2020-05-10
公開日2020-10-28
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for nuclear import selectivity of pioneer transcription factor SOX2.
Nat Commun, 12, 2021
6WX9
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SOX2 bound to Importin-alpha 5
分子名称: Importin subunit alpha-5, Transcription factor SOX-2
著者Bikshapathi, J, Stewart, M, Forwood, J.K, Aragao, D, Roman, N.
登録日2020-05-10
公開日2020-10-28
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis for nuclear import selectivity of pioneer transcription factor SOX2.
Nat Commun, 12, 2021
7SQC
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Ciliary C1 central pair apparatus isolated from Chlamydomonas reinhardtii
分子名称: ADENOSINE-5'-DIPHOSPHATE, CPC1, Calmodulin, ...
著者Gui, M, Wang, X, Dutcher, S.K, Brown, A, Zhang, R.
登録日2021-11-05
公開日2022-04-13
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Ciliary central apparatus structure reveals mechanisms of microtubule patterning.
Nat.Struct.Mol.Biol., 29, 2022
5T94
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Crystal structure of Kap60 bound to yeast RCC1 (Prp20)
分子名称: Guanine nucleotide exchange factor SRM1, Importin subunit alpha
著者Sankhala, R.S, Lokareddy, R.K, Pumroy, R.A, Cingolani, G.
登録日2016-09-09
公開日2017-09-13
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.631 Å)
主引用文献Three-dimensional context rather than NLS amino acid sequence determines importin alpha subtype specificity for RCC1.
Nat Commun, 8, 2017
5TBK
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Crystal structure of human importin a3 bound to RCC1
分子名称: Importin subunit alpha-3, Regulator of chromosome condensation
著者Sankhala, R.S, Lokareddy, R.K, Pumroy, R.A, Cingolani, G.
登録日2016-09-12
公開日2017-09-13
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.45 Å)
主引用文献Three-dimensional context rather than NLS amino acid sequence determines importin alpha subtype specificity for RCC1.
Nat Commun, 8, 2017
1IBR
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COMPLEX OF RAN WITH IMPORTIN BETA
分子名称: GTP-binding nuclear protein RAN, Importin beta-1 subunit, MAGNESIUM ION, ...
著者Vetter, I.R, Arndt, A, Kutay, U, Goerlich, D, Wittinghofer, A.
登録日1999-05-14
公開日1999-06-03
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural view of the Ran-Importin beta interaction at 2.3 A resolution
Cell(Cambridge,Mass.), 97, 1999
3NMZ
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Crystal structure of APC complexed with Asef
分子名称: APC variant protein, Rho guanine nucleotide exchange factor 4
著者Zhang, Z, Chen, L, Gao, L, Lin, K, Wu, G.
登録日2010-06-23
公開日2011-07-06
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.01 Å)
主引用文献Structural basis for the recognition of Asef by adenomatous polyposis coli.
Cell Res., 22, 2012
7RRO
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Structure of the 48-nm repeat doublet microtubule from bovine tracheal cilia
分子名称: Armadillo repeat containing 4, Chromosome 3 C1orf194 homolog, Cilia and flagella associated protein 161, ...
著者Gui, M, Anderson, J.R, Botsch, J.J, Meleppattu, S, Singh, S.K, Zhang, Q, Brown, A.
登録日2021-08-10
公開日2021-10-27
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献De novo identification of mammalian ciliary motility proteins using cryo-EM.
Cell, 184, 2021
5ZHX
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Crystal structure of SmgGDS-558 and farnesylated RhoA complex
分子名称: FARNESYL, Rap1 GTPase-GDP dissociation stimulator 1, Transforming protein RhoA
著者Shimizu, H, Toma-Fukai, S, Shimizu, T.
登録日2018-03-13
公開日2018-09-05
最終更新日2018-10-03
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献GEF mechanism revealed by the structure of SmgGDS-558 and farnesylated RhoA complex and its implication for a chaperone mechanism.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
8TUV
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Merkel Cell Polyomavirus LTA NLSm bound to importin alpha 2
分子名称: 30S ribosomal protein S11, Importin subunit alpha-1, SER-ARG-LYS-ARG-LYS-PHE
著者Cross, E.M, Forwood, J.K, Alvisi, G.
登録日2023-08-17
公開日2024-02-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A functional and structural comparative analysis of large tumor antigens reveals evolution of different importin alpha-dependent nuclear localization signals.
Protein Sci., 33, 2024
3TX7
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Crystal structure of LRH-1/beta-catenin complex
分子名称: (2S)-3-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-[(6E)-HEXADEC-6-ENOYLOXY]PROPYL (8E)-OCTADEC-8-ENOATE, Catenin beta-1, Nuclear receptor subfamily 5 group A member 2
著者Yumoto, F, Fletterick, R.
登録日2011-09-22
公開日2011-12-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.76 Å)
主引用文献Structural basis of coactivation of liver receptor homolog-1 by beta-catenin.
Proc.Natl.Acad.Sci.USA, 109, 2012
3W5K
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Crystal structure of Snail1 and importin beta complex
分子名称: Importin subunit beta-1, ZINC ION, Zinc finger protein SNAI1
著者Choi, S, Yamashita, E, Yasuhara, N, Song, J, Son, S.Y, Won, Y.H, Shin, Y.S, Sekimoto, T, Park, I.Y, Yoneda, Y, Lee, S.J.
登録日2013-01-30
公開日2014-03-05
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis for the selective nuclear import of the C2H2 zinc-finger protein Snail by importin beta.
Acta Crystallogr.,Sect.D, 70, 2014

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