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PDB: 289 件
8HE0
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BU of 8he0 by Molmil
Crystal structure of importin-alpha1 bound to the HIF-1alpha nuclear localization signal (wild-type)
分子名称: Hypoxia-inducible factor 1-alpha, Importin subunit alpha-1
著者Matsuura, Y.
登録日2022-11-07
公開日2023-02-22
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structures of importin-alpha bound to the wild-type and an internal deletion mutant of the bipartite nuclear localization signal of HIF-1 alpha.
Biochem.Biophys.Res.Commun., 652, 2023
8HE3
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BU of 8he3 by Molmil
Crystal structure of importin-alpha1 bound to the HIF-1alpha nuclear localization signal (delta 724-751)
分子名称: Hypoxia-inducible factor 1-alpha, Importin subunit alpha-1, SULFATE ION
著者Matsuura, Y.
登録日2022-11-07
公開日2023-02-22
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structures of importin-alpha bound to the wild-type and an internal deletion mutant of the bipartite nuclear localization signal of HIF-1 alpha.
Biochem.Biophys.Res.Commun., 652, 2023
3T7U
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BU of 3t7u by Molmil
A NeW Crystal structure of APC-ARM
分子名称: Adenomatous polyposis coli protein, PHOSPHATE ION
著者Zhang, Z, Wu, G.
登録日2011-07-31
公開日2011-12-14
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of the armadillo repeat domain of adenomatous polyposis coli which reveals its inherent flexibility
Biochem.Biophys.Res.Commun., 412, 2011
3TJ3
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BU of 3tj3 by Molmil
Structure of importin a5 bound to the N-terminus of Nup50
分子名称: Importin subunit alpha-1, Nuclear pore complex protein Nup50
著者Pumroy, R, Nardozzi, J.D, Hart, D.J, Root, M.J, Cingolani, G.
登録日2011-08-23
公開日2011-11-30
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.702 Å)
主引用文献Nucleoporin Nup50 stabilizes closed conformation of armadillo repeat 10 in importin alpha 5.
J.Biol.Chem., 287, 2012
3TPM
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BU of 3tpm by Molmil
Crystal structure of MAL RPEL domain in complex with importin-alpha
分子名称: Importin subunit alpha-2, MAL
著者Hirano, H, Matsuura, Y.
登録日2011-09-08
公開日2011-10-12
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Sensing actin dynamics: structural basis for G-actin-sensitive nuclear import of MAL
Biochem.Biophys.Res.Commun., 414, 2011
3TPO
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BU of 3tpo by Molmil
Crystal structure of D192A/E396A mutant of mouse importin alpha2
分子名称: Importin subunit alpha-2
著者Hirano, H, Matsuura, Y.
登録日2011-09-08
公開日2011-10-12
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Sensing actin dynamics: structural basis for G-actin-sensitive nuclear import of MAL
Biochem.Biophys.Res.Commun., 414, 2011
3UKW
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BU of 3ukw by Molmil
Mouse importin alpha: Bimax1 peptide complex
分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Bimax1 peptide, Importin subunit alpha-2
著者Marfori, M, Forwood, J.K, Lonhienne, T.G, Kobe, B.
登録日2011-11-10
公開日2012-10-03
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Basis of High-Affinity Nuclear Localization Signal Interactions with Importin-alpha
Traffic, 13, 2012
3UKX
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BU of 3ukx by Molmil
Mouse importin alpha: Bimax2 peptide complex
分子名称: Bimax2 peptide, Importin subunit alpha-2
著者Marfori, M, Forwood, J.K, Lonhienne, T.G, Kobe, B.
登録日2011-11-10
公開日2012-10-03
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Basis of High-Affinity Nuclear Localization Signal Interactions with Importin-alpha
Traffic, 13, 2012
3UKZ
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BU of 3ukz by Molmil
Mouse importin alpha: mouse CBP80 cNLS complex
分子名称: Importin subunit alpha-2, Nuclear cap-binding protein subunit 1
著者Marfori, M, Forwood, J.K, Lonhienne, T.G, Kobe, B.
登録日2011-11-10
公開日2012-10-03
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural Basis of High-Affinity Nuclear Localization Signal Interactions with Importin-alpha
Traffic, 13, 2012
3UL1
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BU of 3ul1 by Molmil
Mouse importin alpha: nucleoplasmin cNLS peptide complex
分子名称: Importin subunit alpha-2, Nucleoplasmin
著者Marfori, M, Forwood, J.K, Lonhienne, T.G, Kobe, B.
登録日2011-11-10
公開日2012-10-03
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural Basis of High-Affinity Nuclear Localization Signal Interactions with Importin-alpha
Traffic, 13, 2012
3UKY
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BU of 3uky by Molmil
Mouse importin alpha: yeast CBP80 cNLS complex
分子名称: Importin subunit alpha-2, Nuclear cap-binding protein complex subunit 1
著者Marfori, M, Forwood, J.K, Lonhienne, T.G, Kobe, B.
登録日2011-11-10
公開日2012-10-03
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural Basis of High-Affinity Nuclear Localization Signal Interactions with Importin-alpha
Traffic, 13, 2012
3UL0
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BU of 3ul0 by Molmil
Mouse importin alpha: mouse CBP80Y8D cNLS complex
分子名称: Importin subunit alpha-2, Nuclear cap-binding protein subunit 1
著者Marfori, M, Forwood, J.K, Lonhienne, T.G, Kobe, B.
登録日2011-11-10
公開日2012-10-03
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Basis of High-Affinity Nuclear Localization Signal Interactions with Importin-alpha
Traffic, 13, 2012
3UVU
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BU of 3uvu by Molmil
Structural basis of nuclear import of Flap endonuclease 1 (FEN1)
分子名称: Flap endonuclease 1 (Fen1) peptide, Importin subunit alpha-2
著者Barros, A.C, Takeda, A.A.S, Fontes, M.R.M.
登録日2011-11-30
公開日2012-06-27
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Structural basis of nuclear import of flap endonuclease 1 (FEN1).
Acta Crystallogr.,Sect.D, 68, 2012
3VE6
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BU of 3ve6 by Molmil
Crystal Structure Analysis of Venezuelan Equine Encephalitis Virus Capsid Protein NLS and Importin Alpha
分子名称: Importin subunit alpha-2, Venezuelan equine encephalitis virus capsid protein NLS
著者Fan, F.
登録日2012-01-07
公開日2012-01-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.829 Å)
主引用文献Crystal Structure Analysis of Venezuelan Equine Encephalitis Virus Capsid Protein NLS and Importin Alpha
To be Published
3WPT
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BU of 3wpt by Molmil
Crystal structure of closed dimer of human importin-alpha1 (Rch1)
分子名称: DI(HYDROXYETHYL)ETHER, Importin subunit alpha-1
著者Miyatake, H, Sanjoh, A, Matsuda, G, Tatsumi, Y, Dohmae, N, Aida, Y.
登録日2014-01-17
公開日2015-01-21
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.629 Å)
主引用文献Crystal structure of closed dimer of human importin-alpha1 (Rch1)
To be Published
3ZIR
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BU of 3zir by Molmil
minor-site specific NLS (B141)
分子名称: B141NLS, IMPORTIN SUBUNIT ALPHA-2
著者Chang, C.-W, Counago, R.M, Williams, S.J, Kobe, B.
登録日2013-01-10
公開日2013-08-21
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Distinctive Conformation of Minor Site-Specific Nuclear Localization Signals Bound to Importin-Alpha
Traffic, 14, 2013
3ZIO
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BU of 3zio by Molmil
minor-site specific NLS (A28)
分子名称: A28NLS, IMPORTIN SUBUNIT ALPHA-2
著者Chang, C.-W, Counago, R.M, Williams, S.J, Kobe, B.
登録日2013-01-10
公開日2013-08-21
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Distinctive Conformation of Minor Site-Specific Nuclear Localization Signals Bound to Importin-Alpha
Traffic, 14, 2013
3ZIQ
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BU of 3ziq by Molmil
minor-site specific NLS (B6)
分子名称: B6NLS, IMPORTIN SUBUNIT ALPHA-2
著者Chang, C.-W, Counago, R.M, Williams, S.J, Kobe, B.
登録日2013-01-10
公開日2013-08-21
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Distinctive Conformation of Minor Site-Specific Nuclear Localization Signals Bound to Importin-Alpha
Traffic, 14, 2013
3ZIN
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BU of 3zin by Molmil
Gu_alpha_helicase
分子名称: IMPORTIN SUBUNIT ALPHA-2, NUCLEOLAR RNA HELICASE 2
著者Chang, C.-W, Counago, R.M, Williams, S.J, Kobe, B.
登録日2013-01-10
公開日2013-08-21
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Distinctive Conformation of Minor Site-Specific Nuclear Localization Signals Bound to Importin-Alpha
Traffic, 14, 2013
3ZIP
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BU of 3zip by Molmil
minor-site specific NLS (A58)
分子名称: A58NLS, IMPORTIN SUBUNIT ALPHA-2
著者Chang, C.-W, Counago, R.M, Williams, S.J, Kobe, B.
登録日2013-01-10
公開日2013-08-21
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Distinctive Conformation of Minor Site-Specific Nuclear Localization Signals Bound to Importin-Alpha
Traffic, 14, 2013
7N6G
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BU of 7n6g by Molmil
C1 of central pair
分子名称: CPC1, Calmodulin, DPY30, ...
著者Han, L, Zhang, K.
登録日2021-06-08
公開日2022-05-18
最終更新日2022-06-01
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Cryo-EM structure of an active central apparatus.
Nat.Struct.Mol.Biol., 29, 2022
3FEY
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BU of 3fey by Molmil
Crystal structure of the CBC-importin alpha complex.
分子名称: Importin subunit alpha-2, Nuclear cap-binding protein subunit 1, Nuclear cap-binding protein subunit 2
著者Dias, S.M.G, Ambrosio, A.L.B, Cerione, R.A.
登録日2008-12-01
公開日2009-08-11
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The molecular basis for the regulation of the cap-binding complex by the importins.
Nat.Struct.Mol.Biol., 16, 2009
3FEX
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BU of 3fex by Molmil
Crystal structure of the CBC-importin alpha complex.
分子名称: Importin subunit alpha-2, Nuclear cap-binding protein subunit 1, Nuclear cap-binding protein subunit 2
著者Dias, S.M.G, Ambrosio, A.L.B, Cerione, R.A.
登録日2008-12-01
公開日2009-08-11
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.549 Å)
主引用文献The molecular basis for the regulation of the cap-binding complex by the importins.
Nat.Struct.Mol.Biol., 16, 2009
1WA5
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BU of 1wa5 by Molmil
Structure of the Cse1:Imp-alpha:RanGTP complex
分子名称: GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, Importin alpha re-exporter, ...
著者Stewart, M.
登録日2004-10-23
公開日2004-12-13
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for the assembly of a nuclear export complex.
Nature, 432, 2004
6WX7
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BU of 6wx7 by Molmil
SOX2 bound to Importin-alpha 2
分子名称: Importin subunit alpha-1, Transcription factor SOX-2
著者Bikshapathi, J, Stewart, M, Forwood, J.K, Aragao, D, Roman, N.
登録日2020-05-09
公開日2020-10-28
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural basis for nuclear import selectivity of pioneer transcription factor SOX2.
Nat Commun, 12, 2021

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