3MFV
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1ZPE
| Arginase I covalently modified with butylamine at Q19C | 分子名称: | Arginase 1, MANGANESE (II) ION | 著者 | Colleluori, D.M, Reczkowski, R.S, Emig, F.A, Cama, E, Cox, J.D, Scolnick, L.R, Compher, K, Jude, K, Han, S, Viola, R.E, Christianson, D.W, Ash, D.E. | 登録日 | 2005-05-16 | 公開日 | 2005-12-06 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Probing the role of the hyper-reactive histidine residue of arginase. Arch.Biochem.Biophys., 444, 2005
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6KSY
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6QAF
| Crystal structure of human Arginase-1 at pH 9.0 in complex with CB-1158/INCB001158 | 分子名称: | Arginase-1, MANGANESE (II) ION, SODIUM ION, ... | 著者 | Grobben, Y, Uitdehaag, J.C.M, Tabak, W.W.A, Zaman, G.J.R. | 登録日 | 2018-12-19 | 公開日 | 2019-12-11 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | 主引用文献 | Structural insights into human Arginase-1 pH dependence and its inhibition by the small molecule inhibitor CB-1158. J Struct Biol X, 4, 2020
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3MFW
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3MMR
| Structure of Plasmodium falciparum Arginase in complex with ABH | 分子名称: | 2(S)-AMINO-6-BORONOHEXANOIC ACID, Arginase, BETA-MERCAPTOETHANOL, ... | 著者 | Dowling, D.P, Ilies, M, Olszewski, K.L, Portugal, S, Mota, M.M, Llinas, M, Christianson, D.W. | 登録日 | 2010-04-20 | 公開日 | 2010-06-23 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Crystal structure of arginase from Plasmodium falciparum and implications for L-arginine depletion in malarial infection . Biochemistry, 49, 2010
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6Q37
| Complex of Arginase 2 with Example 23 | 分子名称: | 1,2-ETHANEDIOL, 3-[(3~{S},4~{R})-4-azanyl-4-carboxy-pyrrolidin-3-yl]propyl-tris(oxidanyl)boranuide, Arginase-2, ... | 著者 | Podjarny, A.D, Van Zandt, M.C, Cousido-Siah, A. | 登録日 | 2018-12-03 | 公開日 | 2019-08-28 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.211 Å) | 主引用文献 | Discovery ofN-Substituted 3-Amino-4-(3-boronopropyl)pyrrolidine-3-carboxylic Acids as Highly Potent Third-Generation Inhibitors of Human Arginase I and II. J.Med.Chem., 62, 2019
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3MJL
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6Q92
| Crystal structure of human Arginase-1 at pH 7.0 in complex with ABH | 分子名称: | 2(S)-AMINO-6-BORONOHEXANOIC ACID, Arginase-1, MANGANESE (II) ION, ... | 著者 | Grobben, Y, Uitdehaag, J.C.M, Zaman, G.J.R. | 登録日 | 2018-12-17 | 公開日 | 2019-12-11 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structural insights into human Arginase-1 pH dependence and its inhibition by the small molecule inhibitor CB-1158. J Struct Biol X, 4, 2020
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4MYL
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4MYF
| Crystal structure of Trypanosoma cruzi formiminoglutamase(oxidized) with Mn2+2 at pH 6.0 | 分子名称: | Formiminoglutamase, MANGANESE (II) ION | 著者 | Hai, Y, Dugery, R.J, Healy, D, Christianson, D.W. | 登録日 | 2013-09-27 | 公開日 | 2013-11-27 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.799 Å) | 主引用文献 | Formiminoglutamase from trypanosoma cruzi is an arginase-like manganese metalloenzyme. Biochemistry, 52, 2013
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4MYK
| Crystal structure of Trypanosoma cruzi formiminoglutamase (oxidized) with Mn2+2 at pH 8.5 | 分子名称: | Formiminoglutamase, MANGANESE (II) ION | 著者 | Hai, Y, Dugery, R.J, Healy, D, Christianson, D.W. | 登録日 | 2013-09-27 | 公開日 | 2013-11-27 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.518 Å) | 主引用文献 | Formiminoglutamase from trypanosoma cruzi is an arginase-like manganese metalloenzyme. Biochemistry, 52, 2013
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6LUH
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1XFK
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1ZPG
| Arginase I covalently modified with propylamine at Q19C | 分子名称: | Arginase 1, MANGANESE (II) ION | 著者 | Colleluori, D.M, Reczkowski, R.S, Emig, F.A, Cama, E, Cox, J.D, Scolnick, L.R, Compher, K, Jude, K, Han, S, Viola, R.E, Christianson, D.W, Ash, D.E. | 登録日 | 2005-05-16 | 公開日 | 2005-12-06 | 最終更新日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Probing the role of the hyper-reactive histidine residue of arginase. Arch.Biochem.Biophys., 444, 2005
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2AEB
| Crystal structure of human arginase I at 1.29 A resolution and exploration of inhibition in immune response. | 分子名称: | 2(S)-AMINO-6-BORONOHEXANOIC ACID, Arginase 1, MANGANESE (II) ION | 著者 | Di Costanzo, L, Sabio, G, Mora, A, Rodriguez, P.C, Ochoa, A.C, Centeno, F, Christianson, D.W. | 登録日 | 2005-07-21 | 公開日 | 2005-09-06 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.29 Å) | 主引用文献 | Crystal structure of human arginase I at 1.29 A resolution and exploration of inhibition in the immune response. Proc.Natl.Acad.Sci.Usa, 102, 2005
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2A0M
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6LUG
| Crystal structure of N(omega)-hydroxy-L-arginine hydrolase | 分子名称: | MANGANESE (II) ION, N(omega)-hydroxy-L-arginine amidinohydrolase | 著者 | Oda, K, Matoba, Y. | 登録日 | 2020-01-28 | 公開日 | 2020-06-17 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of an Nomega-hydroxy-L-arginine hydrolase found in the D-cycloserine biosynthetic pathway. Acta Crystallogr D Struct Biol, 76, 2020
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6NFP
| 1.7 Angstrom Resolution Crystal Structure of Arginase from Bacillus subtilis subsp. subtilis str. 168 | 分子名称: | 1,2-ETHANEDIOL, Arginase, CHLORIDE ION, ... | 著者 | Minasov, G, Wawrzak, Z, Evdokimova, E, Grimshaw, S, Kwon, K, Savchenko, A, Satchell, K.J.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2018-12-20 | 公開日 | 2019-01-02 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | 1.7 Angstrom Resolution Crystal Structure of Arginase from Bacillus subtilis subsp. subtilis str. 168 To Be Published
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6NBK
| Crystal structure of Arginase from Bacillus cereus | 分子名称: | Arginase, CALCIUM ION, MANGANESE (II) ION | 著者 | Chang, C, Evdokimova, E, Mcchesney, M, Joachimiak, A, Savchenko, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2018-12-07 | 公開日 | 2018-12-19 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | 主引用文献 | Crystal structure of Arginase from Bacillus cereus To Be Published
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4MXR
| Crystal structure of Trypanosoma cruzi formiminoglutamase with Mn2+2 | 分子名称: | Formiminoglutamase, GLYCEROL, MANGANESE (II) ION | 著者 | Hai, Y, Dugery, R.-J, Healy, D, Christianson, D.W. | 登録日 | 2013-09-26 | 公開日 | 2013-11-27 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.849 Å) | 主引用文献 | Formiminoglutamase from trypanosoma cruzi is an arginase-like manganese metalloenzyme. Biochemistry, 52, 2013
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4MYN
| Crystal structure of Trypanosoma cruzi formiminoglutamase N114H variant with Mn2+2 | 分子名称: | Formiminoglutamase, MANGANESE (II) ION | 著者 | Hai, Y, Dugery, R.J, Healy, D, Christianson, D.W. | 登録日 | 2013-09-27 | 公開日 | 2013-11-27 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.799 Å) | 主引用文献 | Formiminoglutamase from trypanosoma cruzi is an arginase-like manganese metalloenzyme. Biochemistry, 52, 2013
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6V7F
| Human Arginase1 Complexed with Bicyclic Inhibitor Compound 13 | 分子名称: | Arginase-1, MANGANESE (II) ION, {3-[(5R,7S,8S)-8-azaniumyl-8-carboxy-2-azaspiro[4.4]nonan-2-ium-7-yl]propyl}(trihydroxy)borate(1-) | 著者 | Palte, R.L, Lesburg, C.A. | 登録日 | 2019-12-08 | 公開日 | 2020-05-06 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | Discovery and Optimization of Rationally Designed Bicyclic Inhibitors of Human Arginase to Enhance Cancer Immunotherapy. Acs Med.Chem.Lett., 11, 2020
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6V7D
| Human Arginase1 Complexed with Bicyclic Inhibitor Compound 10 | 分子名称: | Arginase-1, MANGANESE (II) ION, {3-[(3aR,4R,5S,6aR)-4-azaniumyl-4-carboxyoctahydrocyclopenta[b]pyrrol-1-ium-5-yl]propyl}(trihydroxy)borate(1-) | 著者 | Palte, R.L, Lesburg, C.A. | 登録日 | 2019-12-08 | 公開日 | 2020-05-06 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | Discovery and Optimization of Rationally Designed Bicyclic Inhibitors of Human Arginase to Enhance Cancer Immunotherapy. Acs Med.Chem.Lett., 11, 2020
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6V7E
| Human Arginase1 Complexed with Bicyclic Inhibitor Compound 12 | 分子名称: | 3-[(5~{S},7~{S},8~{S})-8-azanyl-8-carboxy-1-azaspiro[4.4]nonan-7-yl]propyl-$l^{3}-oxidanyl-bis(oxidanyl)boranuide, Arginase-1, MANGANESE (II) ION | 著者 | Palte, R.L. | 登録日 | 2019-12-08 | 公開日 | 2020-05-06 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Discovery and Optimization of Rationally Designed Bicyclic Inhibitors of Human Arginase to Enhance Cancer Immunotherapy. Acs Med.Chem.Lett., 11, 2020
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