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PDB: 189 件

3MFV
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Crystal structure of human arginase I in complex with 2-aminohomohistidine
分子名称: (2S)-2-amino-4-(2-amino-1H-imidazol-5-yl)butanoic acid, Arginase-1, MANGANESE (II) ION
著者Di Costanzo, L, Christianson, D.W.
登録日2010-04-04
公開日2010-05-05
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献2-aminoimidazole amino acids as inhibitors of the binuclear manganese metalloenzyme human arginase I.
J.Med.Chem., 53, 2010
1ZPE
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Arginase I covalently modified with butylamine at Q19C
分子名称: Arginase 1, MANGANESE (II) ION
著者Colleluori, D.M, Reczkowski, R.S, Emig, F.A, Cama, E, Cox, J.D, Scolnick, L.R, Compher, K, Jude, K, Han, S, Viola, R.E, Christianson, D.W, Ash, D.E.
登録日2005-05-16
公開日2005-12-06
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Probing the role of the hyper-reactive histidine residue of arginase.
Arch.Biochem.Biophys., 444, 2005
6KSY
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Crystal structure of arginase from Zymomonas mobilis ZM4
分子名称: Arginase/agmatinase/formiminoglutamase, ZINC ION
著者Park, S.Y, Hwangbo, S.A.
登録日2019-08-26
公開日2020-08-05
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.649 Å)
主引用文献Characterization of a Dimeric Arginase FromZymomonas mobilisZM4.
Front Microbiol, 10, 2019
6QAF
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Crystal structure of human Arginase-1 at pH 9.0 in complex with CB-1158/INCB001158
分子名称: Arginase-1, MANGANESE (II) ION, SODIUM ION, ...
著者Grobben, Y, Uitdehaag, J.C.M, Tabak, W.W.A, Zaman, G.J.R.
登録日2018-12-19
公開日2019-12-11
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.61 Å)
主引用文献Structural insights into human Arginase-1 pH dependence and its inhibition by the small molecule inhibitor CB-1158.
J Struct Biol X, 4, 2020
3MFW
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Crystal structure of human arginase I in complex with L-2-aminohistidine and sulphate
分子名称: 2-amino-L-histidine, Arginase-1, MANGANESE (II) ION, ...
著者Di Costanzo, L, Christianson, D.W.
登録日2010-04-04
公開日2010-05-05
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献2-aminoimidazole amino acids as inhibitors of the binuclear manganese metalloenzyme human arginase I.
J.Med.Chem., 53, 2010
3MMR
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BU of 3mmr by Molmil
Structure of Plasmodium falciparum Arginase in complex with ABH
分子名称: 2(S)-AMINO-6-BORONOHEXANOIC ACID, Arginase, BETA-MERCAPTOETHANOL, ...
著者Dowling, D.P, Ilies, M, Olszewski, K.L, Portugal, S, Mota, M.M, Llinas, M, Christianson, D.W.
登録日2010-04-20
公開日2010-06-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Crystal structure of arginase from Plasmodium falciparum and implications for L-arginine depletion in malarial infection .
Biochemistry, 49, 2010
6Q37
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Complex of Arginase 2 with Example 23
分子名称: 1,2-ETHANEDIOL, 3-[(3~{S},4~{R})-4-azanyl-4-carboxy-pyrrolidin-3-yl]propyl-tris(oxidanyl)boranuide, Arginase-2, ...
著者Podjarny, A.D, Van Zandt, M.C, Cousido-Siah, A.
登録日2018-12-03
公開日2019-08-28
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.211 Å)
主引用文献Discovery ofN-Substituted 3-Amino-4-(3-boronopropyl)pyrrolidine-3-carboxylic Acids as Highly Potent Third-Generation Inhibitors of Human Arginase I and II.
J.Med.Chem., 62, 2019
3MJL
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BU of 3mjl by Molmil
Crystal structure of human arginase I in complex with 2-aminoimidazole. Resolution 1.90 A.
分子名称: 1H-imidazol-2-amine, Arginase-1, MANGANESE (II) ION
著者Di Costanzo, L, Christianson, D.W.
登録日2010-04-13
公開日2010-05-05
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of human arginase I in complex with 2-aminoimidazole. Resolution 1.90 A.
To be Published
6Q92
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Crystal structure of human Arginase-1 at pH 7.0 in complex with ABH
分子名称: 2(S)-AMINO-6-BORONOHEXANOIC ACID, Arginase-1, MANGANESE (II) ION, ...
著者Grobben, Y, Uitdehaag, J.C.M, Zaman, G.J.R.
登録日2018-12-17
公開日2019-12-11
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural insights into human Arginase-1 pH dependence and its inhibition by the small molecule inhibitor CB-1158.
J Struct Biol X, 4, 2020
4MYL
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Crystal structure of Trypanosoma cruzi Formiminoglutamase (oxidized) at pH 4.6
分子名称: Formiminoglutamase
著者Hai, Y, Dugery, R.J, Healy, D, Christianson, D.W.
登録日2013-09-27
公開日2013-11-27
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.531 Å)
主引用文献Formiminoglutamase from trypanosoma cruzi is an arginase-like manganese metalloenzyme.
Biochemistry, 52, 2013
4MYF
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Crystal structure of Trypanosoma cruzi formiminoglutamase(oxidized) with Mn2+2 at pH 6.0
分子名称: Formiminoglutamase, MANGANESE (II) ION
著者Hai, Y, Dugery, R.J, Healy, D, Christianson, D.W.
登録日2013-09-27
公開日2013-11-27
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.799 Å)
主引用文献Formiminoglutamase from trypanosoma cruzi is an arginase-like manganese metalloenzyme.
Biochemistry, 52, 2013
4MYK
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Crystal structure of Trypanosoma cruzi formiminoglutamase (oxidized) with Mn2+2 at pH 8.5
分子名称: Formiminoglutamase, MANGANESE (II) ION
著者Hai, Y, Dugery, R.J, Healy, D, Christianson, D.W.
登録日2013-09-27
公開日2013-11-27
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.518 Å)
主引用文献Formiminoglutamase from trypanosoma cruzi is an arginase-like manganese metalloenzyme.
Biochemistry, 52, 2013
6LUH
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BU of 6luh by Molmil
High resolution structure of N(omega)-hydroxy-L-arginine hydrolase
分子名称: MAGNESIUM ION, MANGANESE (II) ION, N(omega)-hydroxy-L-arginine amidinohydrolase
著者Oda, K, Matoba, Y.
登録日2020-01-28
公開日2020-09-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structure of an Nomega-hydroxy-L-arginine hydrolase found in the D-cycloserine biosynthetic pathway.
Acta Crystallogr D Struct Biol, 76, 2020
1XFK
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1.8A crystal structure of formiminoglutamase from Vibrio cholerae O1 biovar eltor str. N16961
分子名称: Formimidoylglutamase
著者Wu, R, Zhang, R, Shonda, C, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2004-09-14
公開日2004-10-26
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献1.8A crystal structure of formiminoglutamas from Vibrio cholerae O1 biovar eltor str. N16961
To be Published
1ZPG
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BU of 1zpg by Molmil
Arginase I covalently modified with propylamine at Q19C
分子名称: Arginase 1, MANGANESE (II) ION
著者Colleluori, D.M, Reczkowski, R.S, Emig, F.A, Cama, E, Cox, J.D, Scolnick, L.R, Compher, K, Jude, K, Han, S, Viola, R.E, Christianson, D.W, Ash, D.E.
登録日2005-05-16
公開日2005-12-06
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Probing the role of the hyper-reactive histidine residue of arginase.
Arch.Biochem.Biophys., 444, 2005
2AEB
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BU of 2aeb by Molmil
Crystal structure of human arginase I at 1.29 A resolution and exploration of inhibition in immune response.
分子名称: 2(S)-AMINO-6-BORONOHEXANOIC ACID, Arginase 1, MANGANESE (II) ION
著者Di Costanzo, L, Sabio, G, Mora, A, Rodriguez, P.C, Ochoa, A.C, Centeno, F, Christianson, D.W.
登録日2005-07-21
公開日2005-09-06
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.29 Å)
主引用文献Crystal structure of human arginase I at 1.29 A resolution and exploration of inhibition in the immune response.
Proc.Natl.Acad.Sci.Usa, 102, 2005
2A0M
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BU of 2a0m by Molmil
Arginase superfamily protein from Trypanosoma cruzi
分子名称: ARGINASE SUPERFAMILY PROTEIN, CHLORIDE ION
著者Arakaki, T.L, Merritt, E.A, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
登録日2005-06-16
公開日2005-07-05
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.603 Å)
主引用文献Structural genomics of pathogenic protozoa: an overview.
Methods Mol.Biol., 426, 2008
6LUG
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BU of 6lug by Molmil
Crystal structure of N(omega)-hydroxy-L-arginine hydrolase
分子名称: MANGANESE (II) ION, N(omega)-hydroxy-L-arginine amidinohydrolase
著者Oda, K, Matoba, Y.
登録日2020-01-28
公開日2020-06-17
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of an Nomega-hydroxy-L-arginine hydrolase found in the D-cycloserine biosynthetic pathway.
Acta Crystallogr D Struct Biol, 76, 2020
6NFP
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1.7 Angstrom Resolution Crystal Structure of Arginase from Bacillus subtilis subsp. subtilis str. 168
分子名称: 1,2-ETHANEDIOL, Arginase, CHLORIDE ION, ...
著者Minasov, G, Wawrzak, Z, Evdokimova, E, Grimshaw, S, Kwon, K, Savchenko, A, Satchell, K.J.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2018-12-20
公開日2019-01-02
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献1.7 Angstrom Resolution Crystal Structure of Arginase from Bacillus subtilis subsp. subtilis str. 168
To Be Published
6NBK
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Crystal structure of Arginase from Bacillus cereus
分子名称: Arginase, CALCIUM ION, MANGANESE (II) ION
著者Chang, C, Evdokimova, E, Mcchesney, M, Joachimiak, A, Savchenko, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2018-12-07
公開日2018-12-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Crystal structure of Arginase from Bacillus cereus
To Be Published
4MXR
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BU of 4mxr by Molmil
Crystal structure of Trypanosoma cruzi formiminoglutamase with Mn2+2
分子名称: Formiminoglutamase, GLYCEROL, MANGANESE (II) ION
著者Hai, Y, Dugery, R.-J, Healy, D, Christianson, D.W.
登録日2013-09-26
公開日2013-11-27
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.849 Å)
主引用文献Formiminoglutamase from trypanosoma cruzi is an arginase-like manganese metalloenzyme.
Biochemistry, 52, 2013
4MYN
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Crystal structure of Trypanosoma cruzi formiminoglutamase N114H variant with Mn2+2
分子名称: Formiminoglutamase, MANGANESE (II) ION
著者Hai, Y, Dugery, R.J, Healy, D, Christianson, D.W.
登録日2013-09-27
公開日2013-11-27
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.799 Å)
主引用文献Formiminoglutamase from trypanosoma cruzi is an arginase-like manganese metalloenzyme.
Biochemistry, 52, 2013
6V7F
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Human Arginase1 Complexed with Bicyclic Inhibitor Compound 13
分子名称: Arginase-1, MANGANESE (II) ION, {3-[(5R,7S,8S)-8-azaniumyl-8-carboxy-2-azaspiro[4.4]nonan-2-ium-7-yl]propyl}(trihydroxy)borate(1-)
著者Palte, R.L, Lesburg, C.A.
登録日2019-12-08
公開日2020-05-06
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Discovery and Optimization of Rationally Designed Bicyclic Inhibitors of Human Arginase to Enhance Cancer Immunotherapy.
Acs Med.Chem.Lett., 11, 2020
6V7D
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Human Arginase1 Complexed with Bicyclic Inhibitor Compound 10
分子名称: Arginase-1, MANGANESE (II) ION, {3-[(3aR,4R,5S,6aR)-4-azaniumyl-4-carboxyoctahydrocyclopenta[b]pyrrol-1-ium-5-yl]propyl}(trihydroxy)borate(1-)
著者Palte, R.L, Lesburg, C.A.
登録日2019-12-08
公開日2020-05-06
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Discovery and Optimization of Rationally Designed Bicyclic Inhibitors of Human Arginase to Enhance Cancer Immunotherapy.
Acs Med.Chem.Lett., 11, 2020
6V7E
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Human Arginase1 Complexed with Bicyclic Inhibitor Compound 12
分子名称: 3-[(5~{S},7~{S},8~{S})-8-azanyl-8-carboxy-1-azaspiro[4.4]nonan-7-yl]propyl-$l^{3}-oxidanyl-bis(oxidanyl)boranuide, Arginase-1, MANGANESE (II) ION
著者Palte, R.L.
登録日2019-12-08
公開日2020-05-06
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Discovery and Optimization of Rationally Designed Bicyclic Inhibitors of Human Arginase to Enhance Cancer Immunotherapy.
Acs Med.Chem.Lett., 11, 2020

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件を2024-10-16に公開中

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