6NBK

Crystal structure of Arginase from Bacillus cereus

Summary for 6NBK

• Entry DOI: 10.2210/pdb6nbk/pdb
• Descriptor: Arginase, MANGANESE (II) ION, CALCIUM ION, ... (4 entities in total)
• Functional Keywords: csgid, structural genomics, arginase, center for structural genomics of infectious diseases, hydrolase
• Biological source: Bacillus thuringiensis DB27
• Total number of polymer chains: 6
• Total formula weight: 194988.10

Authors

Chang, C.,Evdokimova, E.,Mcchesney, M.,Joachimiak, A.,Savchenko, A.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2018-12-07, release date: 2018-12-19, Last modification date: 2026-03-25)

Primary citation

Inniss, N.L.,Minasov, G.,Chang, C.,Tan, K.,Kim, Y.,Maltseva, N.,Stogios, P.,Filippova, E.,Michalska, K.,Osipiuk, J.,Jaroszewki, L.,Godzik, A.,Savchenko, A.,Joachimiak, A.,Anderson, W.F.,Satchell, K.J.F.
Structural genomics of bacterial drug targets: Application of a high-throughput pipeline to solve 58 protein structures from pathogenic and related bacteria.
Microbiol Resour Announc, 14:e0020025-e0020025, 2025

PubMed Abstract: Antibiotic resistance remains a leading cause of severe infections worldwide. Small changes in protein sequence can impact antibiotic efficacy. Here, we report deposition of 58 X-ray crystal structures of bacterial proteins that are known targets for antibiotics, which expands knowledge of structural variation to support future antibiotic discovery or modifications.

PubMed: 40391899
DOI: 10.1128/mra.00200-25

Experimental method

X-RAY DIFFRACTION (1.91 Å)