6NPK
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![BU of 6npk by Molmil](/molmil-images/mine/6npk) | Structure of the TM domain | 分子名称: | Solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 著者 | Feng, L, Liao, M.F, Orlando, B, Zhang, J.R. | 登録日 | 2019-01-17 | 公開日 | 2019-07-31 | 最終更新日 | 2019-08-28 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structure and mechanism of the cation-chloride cotransporter NKCC1. Nature, 572, 2019
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6NPH
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![BU of 6nph by Molmil](/molmil-images/mine/6nph) | Structure of NKCC1 TM domain | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CHLORIDE ION, POTASSIUM ION, ... | 著者 | Feng, L, Liao, M.F, Orlando, B, Zhang, J.R. | 登録日 | 2019-01-17 | 公開日 | 2019-07-31 | 最終更新日 | 2020-01-29 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structure and mechanism of the cation-chloride cotransporter NKCC1. Nature, 572, 2019
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7D99
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![BU of 7d99 by Molmil](/molmil-images/mine/7d99) | human potassium-chloride co-transporter KCC4 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, POTASSIUM ION, ... | 著者 | Xie, Y, Chang, S, Zhao, C, Ye, S, Guo, J. | 登録日 | 2020-10-12 | 公開日 | 2020-12-30 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structures and an activation mechanism of human potassium-chloride cotransporters. Sci Adv, 6, 2020
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6PZT
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![BU of 6pzt by Molmil](/molmil-images/mine/6pzt) | cryo-EM structure of human NKCC1 | 分子名称: | Solute carrier family 12 member 2 | 著者 | Cao, E, Wang, Q, Yang, X. | 登録日 | 2019-08-01 | 公開日 | 2020-03-25 | 実験手法 | ELECTRON MICROSCOPY (3.46 Å) | 主引用文献 | Structure of the human cation-chloride cotransporter NKCC1 determined by single-particle electron cryo-microscopy. Nat Commun, 11, 2020
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6UKN
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![BU of 6ukn by Molmil](/molmil-images/mine/6ukn) | Cryo-EM structure of the potassium-chloride cotransporter KCC4 in lipid nanodiscs | 分子名称: | CHLORIDE ION, POTASSIUM ION, Solute carrier family 12 member 7, ... | 著者 | Reid, M.S, Kern, D.M, Brohawn, S.G. | 登録日 | 2019-10-05 | 公開日 | 2020-06-10 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.65 Å) | 主引用文献 | Cryo-EM structure of the potassium-chloride cotransporter KCC4 in lipid nanodiscs. Elife, 9, 2020
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7ZGO
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![BU of 7zgo by Molmil](/molmil-images/mine/7zgo) | Cryo-EM structure of human NKCC1 (TM domain) | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CHLORIDE ION, CHOLESTEROL HEMISUCCINATE, ... | 著者 | Nissen, P, Fenton, R, Neumann, C, Lindtoft Rosenbaek, L, Kock Flygaard, R, Habeck, M, Lykkegaard Karlsen, J, Wang, Y, Lindorff-Larsen, K, Gad, H, Hartmann, R, Lyons, J. | 登録日 | 2022-04-04 | 公開日 | 2022-10-05 | 最終更新日 | 2023-04-19 | 実験手法 | ELECTRON MICROSCOPY (2.55 Å) | 主引用文献 | Cryo-EM structure of the human NKCC1 transporter reveals mechanisms of ion coupling and specificity. Embo J., 41, 2022
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6KKU
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![BU of 6kku by Molmil](/molmil-images/mine/6kku) | human KCC1 structure determined in NaCl and GDN | 分子名称: | 2-[2-[(1~{S},2~{S},4~{S},5'~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxyethyl]propane-1,3-diol, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | 著者 | Liu, S, Chang, S, Ye, S, Bai, X, Guo, J. | 登録日 | 2019-07-27 | 公開日 | 2019-10-23 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Cryo-EM structures of the human cation-chloride cotransporter KCC1. Science, 366, 2019
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6KKT
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![BU of 6kkt by Molmil](/molmil-images/mine/6kkt) | human KCC1 structure determined in KCl and lipid nanodisc | 分子名称: | 2-[2-[(1~{S},2~{S},4~{S},5'~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxyethyl]propane-1,3-diol, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | 著者 | Liu, S, Chang, S, Ye, S, Bai, X, Guo, J. | 登録日 | 2019-07-27 | 公開日 | 2019-10-23 | 最終更新日 | 2020-08-12 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Cryo-EM structures of the human cation-chloride cotransporter KCC1. Science, 366, 2019
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6KKR
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![BU of 6kkr by Molmil](/molmil-images/mine/6kkr) | human KCC1 structure determined in KCl and detergent GDN | 分子名称: | 2-[2-[(1~{S},2~{S},4~{S},5'~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxyethyl]propane-1,3-diol, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | 著者 | Liu, S, Chang, S, Ye, S, Bai, X, Guo, J. | 登録日 | 2019-07-27 | 公開日 | 2019-10-23 | 最終更新日 | 2020-08-12 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Cryo-EM structures of the human cation-chloride cotransporter KCC1. Science, 366, 2019
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6Y5V
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![BU of 6y5v by Molmil](/molmil-images/mine/6y5v) | Structure of Human Potassium Chloride Transporter KCC3b (S45D/T940D/T997D) in KCl | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Solute carrier family 12 member 6, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Chi, G, Man, H, Ebenhoch, R, Reggiano, G, Pike, A.C.W, Wang, D, McKinley, G, Mukhopadhyay, S.M.M, MacLean, E.M, Chalk, R, Moreau, C, Snee, M, Bohstedt, T, Singh, N.K, Abrusci, P, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Marsden, B.D, Burgess-Brown, N.A, DiMaio, F, Duerr, K.L. | 登録日 | 2020-02-25 | 公開日 | 2020-07-15 | 最終更新日 | 2021-07-28 | 実験手法 | ELECTRON MICROSCOPY (4.08 Å) | 主引用文献 | Phospho-regulation, nucleotide binding and ion access control in potassium-chloride cotransporters. Embo J., 40, 2021
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6Y5R
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![BU of 6y5r by Molmil](/molmil-images/mine/6y5r) | Structure of Human Potassium Chloride Transporter KCC3 S45D/T940D/T997D in NaCl | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Solute carrier family 12 member 6, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Chi, G, Man, H, Ebenhoch, R, Reggiano, G, Pike, A.C.W, Wang, D, McKinley, G, Mukhopadhyay, S.M.M, MacLean, B, Chalk, R, Moreau, C, Snee, M, Bohstedt, T, Singh, N.K, Abrusci, P, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Marsden, B.D, Burgess-Brown, N.A, DiMaio, F, Duerr, K.L, Structural Genomics Consortium (SGC) | 登録日 | 2020-02-25 | 公開日 | 2020-03-11 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.76 Å) | 主引用文献 | Structure of Human Potassium Chloride Transporter KCC3 in NaCl To be published
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7NGB
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![BU of 7ngb by Molmil](/molmil-images/mine/7ngb) | Structure of Wild-Type Human Potassium Chloride Transporter KCC3 in NaCl (LMNG/CHS) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform 2 of Solute carrier family 12 member 6, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Chi, G, Man, H, Pike, A.C.W, Wang, D, McKinley, G, Mukhopadhyay, S.M.M, MacLean, E.M, Chalk, R, Moreau, C, Snee, M, Abrusci, P, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Marsden, B.D, Burgess-Brown, N.A, Duerr, K.L. | 登録日 | 2021-02-09 | 公開日 | 2021-06-09 | 最終更新日 | 2021-07-28 | 実験手法 | ELECTRON MICROSCOPY (3.64 Å) | 主引用文献 | Phospho-regulation, nucleotide binding and ion access control in potassium-chloride cotransporters. Embo J., 40, 2021
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7MXO
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![BU of 7mxo by Molmil](/molmil-images/mine/7mxo) | CryoEM structure of human NKCC1 | 分子名称: | CHLORIDE ION, POTASSIUM ION, Solute carrier family 12 member 2 | 著者 | Moseng, M.A. | 登録日 | 2021-05-19 | 公開日 | 2022-09-28 | 最終更新日 | 2023-05-31 | 実験手法 | ELECTRON MICROSCOPY (3.47 Å) | 主引用文献 | Inhibition mechanism of NKCC1 involves the carboxyl terminus and long-range conformational coupling. Sci Adv, 8, 2022
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7N3N
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![BU of 7n3n by Molmil](/molmil-images/mine/7n3n) | CryoEM structure of human NKCC1 state Fu-I | 分子名称: | 5-(AMINOSULFONYL)-4-CHLORO-2-[(2-FURYLMETHYL)AMINO]BENZOIC ACID, Solute carrier family 12 member 2 | 著者 | Moseng, M.A. | 登録日 | 2021-06-01 | 公開日 | 2022-09-28 | 最終更新日 | 2023-05-31 | 実験手法 | ELECTRON MICROSCOPY (3.33 Å) | 主引用文献 | Inhibition mechanism of NKCC1 involves the carboxyl terminus and long-range conformational coupling. Sci Adv, 8, 2022
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7YG1
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![BU of 7yg1 by Molmil](/molmil-images/mine/7yg1) | Cryo-EM structure of the C-terminal domain of the human sodium-chloride cotransporter | 分子名称: | Solute carrier family 12 member 3 | 著者 | Nan, J, Yang, X.M, Shan, Z.Y, Yuan, Y.F, Zhang, Y.Q. | 登録日 | 2022-07-09 | 公開日 | 2022-11-23 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.77 Å) | 主引用文献 | Cryo-EM structure of the human sodium-chloride cotransporter NCC. Sci Adv, 8, 2022
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7YG0
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![BU of 7yg0 by Molmil](/molmil-images/mine/7yg0) | Cryo-EM structure of human sodium-chloride cotransporter | 分子名称: | Solute carrier family 12 member 3 | 著者 | Nan, J, Yang, X.M, Shan, Z.Y, Yuan, Y.F, Zhang, Y.Q. | 登録日 | 2022-07-09 | 公開日 | 2022-11-23 | 実験手法 | ELECTRON MICROSCOPY (3.75 Å) | 主引用文献 | Cryo-EM structure of the human sodium-chloride cotransporter NCC. Sci Adv, 8, 2022
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7Y6I
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![BU of 7y6i by Molmil](/molmil-images/mine/7y6i) | Cryo-EM structure of human sodium-chloride cotransporter | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 1-O-OCTADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Nan, J, Yang, X, Shan, Z, Yuan, Y, Zhang, Y.Q. | 登録日 | 2022-06-20 | 公開日 | 2022-11-23 | 実験手法 | ELECTRON MICROSCOPY (2.85 Å) | 主引用文献 | Cryo-EM structure of the human sodium-chloride cotransporter NCC. Sci Adv, 8, 2022
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7D14
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![BU of 7d14 by Molmil](/molmil-images/mine/7d14) | Mouse KCC2 | 分子名称: | Solute carrier family 12 member 5 | 著者 | Zhang, S, Yang, M. | 登録日 | 2020-09-13 | 公開日 | 2021-04-14 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | The structural basis of function and regulation of neuronal cotransporters NKCC1 and KCC2. Commun Biol, 4, 2021
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7D10
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![BU of 7d10 by Molmil](/molmil-images/mine/7d10) | Human NKCC1 | 分子名称: | PALMITIC ACID, Solute carrier family 12 member 2 | 著者 | Zhang, S, Yang, M. | 登録日 | 2020-09-12 | 公開日 | 2021-04-14 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.52 Å) | 主引用文献 | The structural basis of function and regulation of neuronal cotransporters NKCC1 and KCC2. Commun Biol, 4, 2021
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7D8Z
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![BU of 7d8z by Molmil](/molmil-images/mine/7d8z) | human potassium-chloride co-transporter KCC2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, potassium-chloride cotransporter 2 | 著者 | Xie, Y, Chang, S, Zhao, C, Ye, S, Guo, J. | 登録日 | 2020-10-11 | 公開日 | 2020-12-30 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structures and an activation mechanism of human potassium-chloride cotransporters. Sci Adv, 6, 2020
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7D90
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![BU of 7d90 by Molmil](/molmil-images/mine/7d90) | human potassium-chloride co-transporter KCC3 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, potassium-chloride cotransporter 3 | 著者 | Xie, Y, Chang, S, Zhao, C, Ye, S, Guo, J. | 登録日 | 2020-10-12 | 公開日 | 2020-12-30 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structures and an activation mechanism of human potassium-chloride cotransporters. Sci Adv, 6, 2020
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7AIO
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![BU of 7aio by Molmil](/molmil-images/mine/7aio) | Structure of Human Potassium Chloride Transporter KCC3 S45D/T940D/T997D in NaCl (Subclass) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Solute carrier family 12 member 6, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Chi, G, Man, H, Ebenhoch, R, Reggiano, G, Pike, A.C.W, Wang, D, McKinley, G, Mukhopadhyay, S.M.M, MacLean, E.M, Chalk, R, Moreau, C, Snee, M, Bohstedt, T, Singh, N.K, Abrusci, P, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Marsden, B.D, Burgess-Brown, N.A, DiMaio, F, Duerr, K.L, Structural Genomics Consortium (SGC) | 登録日 | 2020-09-28 | 公開日 | 2021-06-02 | 最終更新日 | 2021-07-28 | 実験手法 | ELECTRON MICROSCOPY (3.31 Å) | 主引用文献 | Phospho-regulation, nucleotide binding and ion access control in potassium-chloride cotransporters. Embo J., 40, 2021
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7AIN
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![BU of 7ain by Molmil](/molmil-images/mine/7ain) | Structure of Human Potassium Chloride Transporter KCC3 S45D/T940D/T997D in NaCl (Reference Map) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform 2 of Solute carrier family 12 member 6, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Chi, G, Man, H, Ebenhoch, R, Reggiano, G, Pike, A.C.W, Wang, D, McKinley, G, Mukhopadhyay, S.M.M, MacLean, E.M, Chalk, R, Moreau, C, Snee, M, Bohstedt, T, Singh, N.K, Abrusci, P, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Marsden, B.D, Burgess-Brown, N.A, DiMaio, F, Duerr, K.L, Structural Genomics Consortium (SGC) | 登録日 | 2020-09-28 | 公開日 | 2021-06-02 | 最終更新日 | 2021-07-28 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Phospho-regulation, nucleotide binding and ion access control in potassium-chloride cotransporters. Embo J., 40, 2021
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7AIR
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![BU of 7air by Molmil](/molmil-images/mine/7air) | Structure of Human Potassium Chloride Transporter KCC1 in NaCl (Subclass 2) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ... | 著者 | Ebenhoch, R, Chi, G, Man, H, Wang, D, McKinley, G, Mukhopadhyay, S.M.M, MacLean, E.M, Chalk, R, Moreau, C, Snee, M, Bohstedt, T, Singh, N.K, Abrusci, P, Liko, I, Tehan, B.G, Almeida, F.G, Arrowsmith, C.H, Tang, H, Robinson, C.V, Bountra, C, Edwards, A.M, Marsden, B.D, Burgess-Brown, N.A, Duerr, K.L, Structural Genomics Consortium (SGC) | 登録日 | 2020-09-28 | 公開日 | 2021-06-02 | 最終更新日 | 2021-07-28 | 実験手法 | ELECTRON MICROSCOPY (3.66 Å) | 主引用文献 | Phospho-regulation, nucleotide binding and ion access control in potassium-chloride cotransporters. Embo J., 40, 2021
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7AIP
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![BU of 7aip by Molmil](/molmil-images/mine/7aip) | Structure of Human Potassium Chloride Transporter KCC1 in NaCl (Reference Map) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Ebenhoch, R, Chi, G, Man, H, Wang, D, McKinley, G, Mukhopadhyay, S.M.M, MacLean, E.M, Chalk, R, Moreau, C, Snee, M, Bohstedt, T, Liko, I, Tehan, B.G, Almeida, F.G, Elkins, J, Singh, N.K, Abrusci, P, Arrowsmith, C.H, Tang, H, Robinson, C.V, Bountra, C, Edwards, A.M, Marsden, B.D, Burgess-Brown, N.A, Duerr, K.L, Structural Genomics Consortium (SGC) | 登録日 | 2020-09-28 | 公開日 | 2021-06-02 | 最終更新日 | 2021-07-28 | 実験手法 | ELECTRON MICROSCOPY (3.12 Å) | 主引用文献 | Phospho-regulation, nucleotide binding and ion access control in potassium-chloride cotransporters. Embo J., 40, 2021
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