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PDB: 424 件
7W75
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BU of 7w75 by Molmil
Crystal structure of the K. lactis Bre1 RBD in complex with Rad6, crystal form I
分子名称: E3 ubiquitin-protein ligase BRE1, Ubiquitin-conjugating enzyme E2 2
著者Shi, M, Zhao, J, Xiang, S.
登録日2021-12-03
公開日2023-03-29
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural basis for the Rad6 activation by the Bre1 N-terminal domain.
Elife, 12, 2023
7W76
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BU of 7w76 by Molmil
Crystal structure of the K. lactis Bre1 RBD in complex with Rad6, crystal form II
分子名称: E3 ubiquitin-protein ligase BRE1, GLYCEROL, SULFATE ION, ...
著者Shi, M, Zhao, J, Xiang, S.
登録日2021-12-03
公開日2023-03-29
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Structural basis for the Rad6 activation by the Bre1 N-terminal domain.
Elife, 12, 2023
7WLH
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BU of 7wlh by Molmil
The crystal structure of African swine fever virus I215L
分子名称: E2 ubiquitin-conjugating enzyme
著者Shen, Z, Liang, R, Yang, Y, Peng, G.
登録日2022-01-13
公開日2023-07-19
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献The crystal structure of African swine fever virus I215L
To Be Published
7V8F
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BU of 7v8f by Molmil
Crystal structure of UBE2L3 bound to HOIP RING1 domain.
分子名称: E3 ubiquitin-protein ligase RNF31, Ubiquitin-conjugating enzyme E2 L3, ZINC ION
著者Liu, J, Wang, Y, Pan, L.
登録日2021-08-22
公開日2022-03-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Mechanistic insights into the subversion of the linear ubiquitin chain assembly complex by the E3 ligase IpaH1.4 of Shigella flexneri.
Proc.Natl.Acad.Sci.USA, 119, 2022
7UVC
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BU of 7uvc by Molmil
Rad6(P43L)-Bre1 Complex
分子名称: E3 ubiquitin-protein ligase BRE1, Ubiquitin-conjugating enzyme E2 2
著者Shukla, P.K, Chandrasekharan, M.B.
登録日2022-04-29
公開日2023-01-11
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Structure and functional determinants of Rad6-Bre1 subunits in the histone H2B ubiquitin-conjugating complex.
Nucleic Acids Res., 51, 2023
7UV8
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BU of 7uv8 by Molmil
Rad6-Bre1 Complex
分子名称: E3 ubiquitin-protein ligase BRE1, Ubiquitin-conjugating enzyme E2 2
著者Shukla, P.K, Chandrasekharan, M.B.
登録日2022-04-29
公開日2023-01-11
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure and functional determinants of Rad6-Bre1 subunits in the histone H2B ubiquitin-conjugating complex.
Nucleic Acids Res., 51, 2023
2YB6
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BU of 2yb6 by Molmil
Native human Rad6
分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, UBIQUITIN-CONJUGATING ENZYME E2 B
著者Hibbert, R.G, Sixma, T.K.
登録日2011-03-02
公開日2011-04-20
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献E3 Ligase Rad18 Promotes Monoubiquitination Rather Than Ubiquitin Chain Formation by E2 Enzyme Rad6.
Proc.Natl.Acad.Sci.USA, 108, 2011
2YBF
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BU of 2ybf by Molmil
Complex of Rad18 (Rad6 binding domain) with Rad6b
分子名称: BETA-MERCAPTOETHANOL, E3 UBIQUITIN-PROTEIN LIGASE RAD18, SODIUM ION, ...
著者Hibbert, R.G, Sixma, T.K.
登録日2011-03-08
公開日2011-04-20
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献E3 Ligase Rad18 Promotes Monoubiquitination Rather Than Ubiquitin Chain Formation by E2 Enzyme Rad6.
Proc.Natl.Acad.Sci.USA, 108, 2011
4M1N
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BU of 4m1n by Molmil
Crystal structure of Plasmodium falciparum ubiquitin conjugating enzyme UBC9
分子名称: SODIUM ION, Ubiquitin conjugating enzyme UBC9
著者Boucher, L.E, Reiter, K.H, Bosch, J, Matunis, J.M.
登録日2013-08-03
公開日2013-08-21
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Identification of Biochemically Distinct Properties of the Small Ubiquitin-related Modifier (SUMO) Conjugation Pathway in Plasmodium falciparum.
J.Biol.Chem., 288, 2013
6S98
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BU of 6s98 by Molmil
Crystal structure of the catalytic domain of UBE2S WT.
分子名称: 1,2-ETHANEDIOL, ACETATE ION, SODIUM ION, ...
著者Liess, A.K.L, Lorenz, S.
登録日2019-07-11
公開日2020-10-21
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Dimerization regulates the human APC/C-associated ubiquitin-conjugating enzyme UBE2S.
Sci.Signal., 13, 2020
6S96
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BU of 6s96 by Molmil
Crystal structure of the catalytic domain of UBE2S C118A.
分子名称: FORMIC ACID, SODIUM ION, Ubiquitin-conjugating enzyme E2 S
著者Liess, A.K.L, Lorenz, S.
登録日2019-07-11
公開日2020-10-21
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献Dimerization regulates the human APC/C-associated ubiquitin-conjugating enzyme UBE2S.
Sci.Signal., 13, 2020
2Z5D
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BU of 2z5d by Molmil
Human ubiquitin-conjugating enzyme E2 H
分子名称: SODIUM ION, Ubiquitin-conjugating enzyme E2 H
著者Bochkarev, A, Cui, H, Walker, J.R, Newman, E.M, Mackenzie, F, Battaile, K.P, Sundstrom, M, Arrowsmith, C, Edwards, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2007-07-06
公開日2007-10-09
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen.
MOL.CELL PROTEOMICS, 11, 2012
6SYF
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BU of 6syf by Molmil
Human Ubc9 with covalent isopeptide ligand
分子名称: ACE-ILE-LYS-GLN-GLU, ACE-LEU-ARG-LEU-ARG-GLY-CYS, SUMO-conjugating enzyme UBC9
著者Hofmann, R, Akimoto, G, Wucherpfennig, T.G, Zeymer, C, Bode, J.W.
登録日2019-09-27
公開日2020-08-12
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Lysine acylation using conjugating enzymes for site-specific modification and ubiquitination of recombinant proteins.
Nat.Chem., 12, 2020
4JUE
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BU of 4jue by Molmil
Crystal structure of Plasmodium falciparum ubiquitin conjugating enzyme UBC9
分子名称: Ubiquitin conjugating enzyme UBC9
著者Reiter, K.H, Boucher, L.E, Bosch, J, Matunis, J.M.
登録日2013-03-24
公開日2013-08-21
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.851 Å)
主引用文献Identification of Biochemically Distinct Properties of the Small Ubiquitin-related Modifier (SUMO) Conjugation Pathway in Plasmodium falciparum.
J.Biol.Chem., 288, 2013
6R75
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BU of 6r75 by Molmil
Crystal structure of human Ube2T E54R mutant
分子名称: Ubiquitin-conjugating enzyme E2 T
著者Chaugule, V.K, Rennie, M.L, Walden, H, Arkinson, C, Kamarainen, O, Toth, R.
登録日2019-03-28
公開日2019-10-16
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Allosteric mechanism for site-specific ubiquitination of FANCD2.
Nat.Chem.Biol., 16, 2020
3BZH
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BU of 3bzh by Molmil
Crystal structure of human ubiquitin-conjugating enzyme E2 E1
分子名称: GLYCEROL, Ubiquitin-conjugating enzyme E2 E1
著者Walker, J.R, Avvakumov, G.V, Xue, S, Li, Y, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2008-01-18
公開日2008-02-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen.
Mol Cell Proteomics, 11, 2012
4NR3
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BU of 4nr3 by Molmil
Crystal Structure of a human Mms2/Ubc13 L121G mutant
分子名称: Ubiquitin-conjugating enzyme E2 N, Ubiquitin-conjugating enzyme E2 variant 2
著者Hodge, C.D, Edwards, R.A, Glover, J.N.M.
登録日2013-11-26
公開日2014-12-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.802 Å)
主引用文献Stochastic gate dynamics regulate the catalytic activity of ubiquitination enzymes.
J.Am.Chem.Soc., 136, 2014
4NRI
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BU of 4nri by Molmil
Crystal Structure of a human Mms2/Ubc13 A122G mutant
分子名称: GLYCEROL, Ubiquitin-conjugating enzyme E2 N, Ubiquitin-conjugating enzyme E2 variant 2
著者Hodge, C.D, Edwards, R.A, Glover, J.N.M.
登録日2013-11-26
公開日2014-12-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Stochastic gate dynamics regulate the catalytic activity of ubiquitination enzymes.
J.Am.Chem.Soc., 136, 2014
4NRG
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BU of 4nrg by Molmil
Crystal Structure of a human Mms2/Ubc13 D118G mutant
分子名称: Ubiquitin-conjugating enzyme E2 N, Ubiquitin-conjugating enzyme E2 variant 2
著者Hodge, C.D, Edwards, R.A, Glover, J.N.M.
登録日2013-11-26
公開日2014-12-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Stochastic gate dynamics regulate the catalytic activity of ubiquitination enzymes.
J.Am.Chem.Soc., 136, 2014
5A4P
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BU of 5a4p by Molmil
Structure of UBE2Z provides functional insight into specificity in the FAT10 conjugation machinery
分子名称: DI(HYDROXYETHYL)ETHER, MALONATE ION, UBIQUITIN-CONJUGATING ENZYME E2 Z
著者Schelpe, J, Monte, D, Dewitte, F, Sixma, T.K, Rucktooa, P.
登録日2015-06-11
公開日2015-11-18
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure of Ube2Z Provides Functional Insight Into Specificity in the Fat10 Conjugation Machinery
J.Biol.Chem., 291, 2016
4DS2
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BU of 4ds2 by Molmil
Ubiquitin conjugating enzyme (putative) from Trypanosoma cruzi
分子名称: Ubiquitin-conjugating enzyme E2, putative
著者Merritt, E.A, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
登録日2012-02-17
公開日2012-02-29
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.63 Å)
主引用文献Ubiquitin conjugating enzyme (putative) from Trypanosoma cruzi
To be Published
4ONL
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BU of 4onl by Molmil
Crystal structure of human Mms2/Ubc13_D81N, R85S, A122V, N123P
分子名称: Ubiquitin-conjugating enzyme E2 N, Ubiquitin-conjugating enzyme E2 variant 2
著者Hodge, C.D, Edwards, R.A, Glover, J.N.M.
登録日2014-01-28
公開日2015-05-06
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Covalent Inhibition of Ubc13 Affects Ubiquitin Signaling and Reveals Active Site Elements Important for Targeting.
Acs Chem.Biol., 10, 2015
7YW1
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BU of 7yw1 by Molmil
crystal structure of UBE2O
分子名称: (E3-independent) E2 ubiquitin-conjugating enzyme UBE2O
著者Fu, Z, Zhu, W, Huang, H.
登録日2022-08-20
公開日2023-08-30
実験手法X-RAY DIFFRACTION (3.27 Å)
主引用文献crystal structure of UBE2O
To Be Published
2GJD
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BU of 2gjd by Molmil
Distinct functional domains of Ubc9 dictate cell survival and resistance to genotoxic stress
分子名称: Ubiquitin-conjugating enzyme E2-18 kDa
著者van Waardenburg, R.C, Duda, D.M, Lancaster, C.S, Schulman, B.A, Bjornsti, M.A.
登録日2006-03-30
公開日2006-07-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Distinct functional domains of ubc9 dictate cell survival and resistance to genotoxic stress.
Mol.Cell.Biol., 26, 2006
2KLY
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BU of 2kly by Molmil
Solution structure of human ubiquitin conjugating enzyme Ube2g2
分子名称: Ubiquitin-conjugating enzyme E2 G2
著者Ju, T, Bocik, W, Majumdar, A, Tolman, J.R.
登録日2009-07-10
公開日2010-03-02
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure and dynamics of human ubiquitin conjugating enzyme Ube2g2.
Proteins, 78, 2010

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