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PDB: 202 件
3FBK
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Crystal structure of the C2 domain of the human regulator of G-protein signaling 3 isoform 6 (RGP3), Northeast Structural Genomics Consortium Target HR5550A
分子名称: Regulator of G-protein signaling 3, SULFATE ION
著者Forouhar, F, Lew, S, Seetharaman, J, Mao, L, Xiao, R, Ciccosanti, C, Foote, E.L, Shastry, R, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
登録日2008-11-19
公開日2008-12-02
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of the C2 domain of the human regulator of G-protein signaling 3 isoform 6 (RGP3), Northeast Structural Genomics Consortium Target HR5550A
To be Published
1V27
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Solution structure of the first C2 domain of RIM2
分子名称: Regulating synaptic membrane exocytosis protein 2
著者Nagashima, T, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2003-10-07
公開日2004-04-07
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Solution structure of the first C2 domain of RIM2
to be published
4WEE
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BU of 4wee by Molmil
High-resolution structure of Synaptotagmin 1 C2A
分子名称: SODIUM ION, SULFATE ION, Synaptotagmin-1
著者Sutton, R.B, Fuson, K.L.
登録日2014-09-09
公開日2014-10-01
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (0.891 Å)
主引用文献High-resolution structure of Synaptotagmin 1 C2A
To Be Published
5A52
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The crystal structure of Arabidopsis thaliana CAR1 in complex with one calcium ion
分子名称: CALCIUM ION, CALCIUM-DEPENDENT LIPID-BINDING DOMAIN-CONTAINING PROTEIN, GLYCEROL, ...
著者Fernandez, D, Marquez, J.A.
登録日2015-06-16
公開日2016-03-02
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Calcium-Dependent Oligomerization of Car Proteins at Cell Membrane Modulates Aba Signaling.
Proc.Natl.Acad.Sci.USA, 113, 2016
2Q3X
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BU of 2q3x by Molmil
The RIM1alpha C2B domain
分子名称: CHLORIDE ION, Regulating synaptic membrane exocytosis protein 1, SODIUM ION, ...
著者Guan, R, Dai, H, Tomchick, D.R, Machius, M, Sudhof, T.C, Rizo, J.
登録日2007-05-30
公開日2007-08-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Crystal Structure of the RIM1alpha C(2)B Domain at 1.7 A Resolution.
Biochemistry, 46, 2007
1A25
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C2 DOMAIN FROM PROTEIN KINASE C (BETA)
分子名称: CALCIUM ION, O-PHOSPHOETHANOLAMINE, PROTEIN KINASE C (BETA)
著者Sutton, R.B, Sprang, S.R.
登録日1998-01-16
公開日1998-05-06
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure of the protein kinase Cbeta phospholipid-binding C2 domain complexed with Ca2+.
Structure, 6, 1998
8C5H
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NbSyt1 anti-(rat Synaptotagmin-1) nanobody bound to target cytosolic domain of Synaptotagmin-1
分子名称: CALCIUM ION, GLYCEROL, NbSyt1 nanobody, ...
著者Martinez-Carranza, M, Stenmark, P.
登録日2023-01-09
公開日2023-08-02
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献A Versatile Synaptotagmin-1 Nanobody Provides Perturbation-Free Live Synaptic Imaging And Low Linkage-Error in Super-Resolution Microscopy.
Small Methods, 7, 2023
5YQ3
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BU of 5yq3 by Molmil
Solution NMR Structure and Backbone Dynamics of the Partially Disordered Arabidopsis thaliana Phloem Protein 16-1, A Putative mRNA Transporter
分子名称: At3g55470
著者Bhuyan, A.K, Sashi, P.
登録日2017-11-04
公開日2018-04-18
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution NMR Structure and Backbone Dynamics of Partially Disordered Arabidopsis thaliana Phloem Protein 16-1, a Putative mRNA Transporter.
Biochemistry, 57, 2018
4DNL
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Crystal structure of a C2 domain of a protein kinase C alpha (PRKCA) from Homo sapiens at 1.90 A resolution
分子名称: Protein kinase C alpha type, SODIUM ION
著者Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL)
登録日2012-02-08
公開日2012-02-22
最終更新日2023-02-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of a C2 domain of a protein kinase C alpha (PRKCA) from Homo sapiens at 1.90 A resolution
To be published
6IEJ
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The C2 domain of cytosolic phospholipase A2 alpha bound to phosphatidylcholine
分子名称: 1,2-dihexanoyl-sn-glycero-3-phosphocholine, CALCIUM ION, Cytosolic phospholipase A2, ...
著者Hirano, Y, Gao, Y.G, Stephenson, D.J, Vu, N.T, Malinina, L, Chalfant, C.E, Patel, D.J, Brown, R.E.
登録日2018-09-14
公開日2019-05-22
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.206 Å)
主引用文献Structural basis of phosphatidylcholine recognition by the C2-domain of cytosolic phospholipase A2alpha.
Elife, 8, 2019
4TS6
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BU of 4ts6 by Molmil
Crystal structure of the RIM C2A domain from Drosophila.
分子名称: GLYCEROL, Rab3 interacting molecule variant 2
著者Hatzopoulos, G.N, Shiroma, J, Vakonakis, I.
登録日2014-06-18
公開日2015-07-01
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Crystal structure of the RIM C2A domain from Drosophila.
To Be Published
4NS0
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BU of 4ns0 by Molmil
The C2A domain of Rabphilin 3A in complex with PI(4,5)P2
分子名称: Rabphilin-3A, SULFATE ION, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
著者Guillen, J, Ferrer-Orta, C, Buxaderas, M, Perez-sanchez, D, Guerrero-Valero, M, Luengo-Gil, G, Pous, J, Guerra, P, Gomez-Fernandez, J.C, Verdaguer, N, Corbalan-Garcia, S.
登録日2013-11-27
公開日2013-12-25
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural insights into the Ca2+ and PI(4,5)P2 binding modes of the C2 domains of rabphilin 3A and synaptotagmin 1.
Proc.Natl.Acad.Sci.USA, 110, 2013
4NPK
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BU of 4npk by Molmil
Extended-Synaptotagmin 2, C2A- and C2B-domains, calcium bound
分子名称: CALCIUM ION, Extended synaptotagmin-2
著者Tomchick, D.R, Rizo, J, Xu, J.
登録日2013-11-21
公開日2014-01-29
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.552 Å)
主引用文献Structure and ca(2+)-binding properties of the tandem c2 domains of e-syt2.
Structure, 22, 2014
2EP6
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BU of 2ep6 by Molmil
Solution structure of the second C2 domain from human MCTP2 protein
分子名称: MCTP2 protein
著者Nagashima, T, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-03-29
公開日2007-10-02
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the second C2 domain from human MCTP2 protein
To be Published
2ENP
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BU of 2enp by Molmil
Solution structure of the first C2 domain from human B/K protein
分子名称: B/K protein
著者Endo, H, Nagashima, T, Yoshida, M, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-03-28
公開日2007-10-02
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the first C2 domain from human B/K protein
To be Published
3GPE
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BU of 3gpe by Molmil
Crystal Structure Analysis of PKC (alpha)-C2 domain complexed with Ca2+ and PtdIns(4,5)P2
分子名称: CALCIUM ION, PHOSPHATE ION, Protein kinase C alpha type, ...
著者Ferrer-Orta, C, Querol-Audi, J, Fita, I, Verdaguer, N.
登録日2009-03-23
公開日2009-05-05
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural and mechanistic insights into the association of PKCalpha-C2 domain to PtdIns(4,5)P2.
Proc.Natl.Acad.Sci.USA, 106, 2009
6U4W
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BU of 6u4w by Molmil
1.4 A structure of a pathogenic human Syt 1 C2B (D366E)
分子名称: SULFATE ION, Synaptotagmin-1
著者Dominguez, M.J, Bradberry, M.M, Chapman, E.R, Sutton, R.B.
登録日2019-08-26
公開日2020-05-13
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Molecular Basis for Synaptotagmin-1-Associated Neurodevelopmental Disorder.
Neuron, 107, 2020
2R83
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Crystal structure analysis of human synaptotagmin 1 C2A-C2B
分子名称: CHLORIDE ION, Synaptotagmin-1
著者Sutton, R.B, Fuson, K.L, Montes, M, Robert, J.J.
登録日2007-09-10
公開日2008-02-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure of human synaptotagmin 1 C2AB in the absence of Ca2+ reveals a novel domain association.
Biochemistry, 46, 2007
4V11
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Structure of Synaptotagmin-1 with SV2A peptide phosphorylated at Thr84
分子名称: CALCIUM ION, GLYCEROL, SYNAPTIC VESICLE GLYCOPROTEIN 2A, ...
著者Zhang, N, Gordon, S.L, Fritsch, M.J, Esoof, N, Campbell, D, Gourlay, R, Velupillai, S, Macartney, T, Peggie, M, vanAalten, D.M.F, Cousin, M.A, Alessi, D.R.
登録日2014-09-22
公開日2015-02-25
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Phosphorylation of Synaptic Vesicle Protein 2A at Thr84 by Casein Kinase 1 Family Kinases Controls the Specific Retrieval of Synaptotagmin-1.
J.Neurosci., 35, 2015
2UZP
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BU of 2uzp by Molmil
Crystal structure of the C2 domain of human protein kinase C gamma.
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, COBALT (II) ION, ...
著者Pike, A.C.W, Amos, A, Johansson, C, Sobott, F, Savitsky, P, Berridge, G, Fedorov, O, Umeano, C, Gorrec, F, Bunkoczi, G, Debreczeni, J, von Delft, F, Arrowsmith, C.H, Edwards, A, Weigelt, J, Sundstrom, M, Knapp, S.
登録日2007-04-30
公開日2007-05-29
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of C2 Domain of Protein Kinase C Gamma
To be Published
5H4Z
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Crystal structure of S202G mutant of human SYT-5 C2A domain
分子名称: CALCIUM ION, CHLORIDE ION, Synaptotagmin-5
著者Qiu, X, Ge, J, Yan, X, Gao, Y, Teng, M, Niu, L.
登録日2016-11-02
公開日2016-11-30
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.01 Å)
主引用文献Structural analysis of Ca(2+)-binding pocket of synaptotagmin 5 C2A domain
Int. J. Biol. Macromol., 95, 2017
5H4Y
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Crystal structure of human synaptotagmin 5 C2A domain
分子名称: ACETATE ION, CALCIUM ION, Synaptotagmin-5
著者Qiu, X, Gao, Y, Teng, M, Niu, L.
登録日2016-11-02
公開日2016-11-30
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural analysis of Ca(2+)-binding pocket of synaptotagmin 5 C2A domain
Int. J. Biol. Macromol., 95, 2017
3HN8
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Crystal structure of synaptotagmin
分子名称: CALCIUM ION, Synaptotagmin-3, ZINC ION
著者Strop, P, Vrljic, M, Ernst, J, Brunger, A.T.
登録日2009-05-30
公開日2010-02-23
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Molecular mechanism of the synaptotagmin-SNARE interaction in Ca2+-triggered vesicle fusion.
Nat.Struct.Mol.Biol., 17, 2010
1K5W
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THREE-DIMENSIONAL STRUCTURE OF THE SYNAPTOTAGMIN 1 C2B-DOMAIN: SYNAPTOTAGMIN 1 AS A PHOSPHOLIPID BINDING MACHINE
分子名称: CALCIUM ION, Synaptotagmin I
著者Fernandez, I, Arac, D, Ubach, J, Gerber, S.H, Shin, O, Gao, Y, Anderson, R.G.W, Sudhof, T.C, Rizo, J.
登録日2001-10-12
公開日2002-01-23
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Three-dimensional structure of the synaptotagmin 1 C2B-domain: synaptotagmin 1 as a phospholipid binding machine.
Neuron, 32, 2001
1GMI
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Structure of the c2 domain from novel protein kinase C epsilon
分子名称: MAGNESIUM ION, PROTEIN KINASE C, EPSILON TYPE
著者Ochoa, W.F, Garcia-Garcia, J, Fita, I, Corbalan-Garcia, S, Verdaguer, N, Gomez-Fernandez, J.C.
登録日2001-09-14
公開日2001-10-25
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure of the C2 Domain from Novel Protein Kinase Cepsilon. A Membrane Binding Model for Ca(2+ )-Independent C2 Domains
J.Mol.Biol., 311, 2001

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