8D96
| Human DNA polymerase alpha/primase elongation complex I bound to primer/template | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*AP*TP*AP*AP*TP*GP*GP*TP*CP*GP*TP*GP*CP*CP*GP*CP*CP*AP*AP*TP*AP*A)-3'), DNA polymerase alpha catalytic subunit, ... | 著者 | He, Q, Baranovskiy, A, Lim, C, Tahirov, T. | 登録日 | 2022-06-09 | 公開日 | 2023-04-19 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.35 Å) | 主引用文献 | Structures of human primosome elongation complexes. Nat.Struct.Mol.Biol., 30, 2023
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8D9D
| Human DNA polymerase-alpha/primase elongation complex II bound to primer/template | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*AP*TP*GP*GP*TP*CP*GP*TP*GP*CP*CP*GP*CP*CP*AP*AP*TP*AP*A)-3'), DNA polymerase alpha catalytic subunit, ... | 著者 | He, Q, Baranovskiy, A, Lim, C, Tahirov, T. | 登録日 | 2022-06-09 | 公開日 | 2023-04-19 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.59 Å) | 主引用文献 | Structures of human primosome elongation complexes. Nat.Struct.Mol.Biol., 30, 2023
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7U5C
| Cryo-EM structure of human CST bound to DNA polymerase alpha-primase in a recruitment state | 分子名称: | CST complex subunit CTC1, CST complex subunit STN1, CST complex subunit TEN1, ... | 著者 | Cai, S.W, Zinder, J.C, Svetlov, V, Bush, M.W, Nudler, E, Walz, T, de Lange, T. | 登録日 | 2022-03-02 | 公開日 | 2022-05-18 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | 主引用文献 | Cryo-EM structure of the human CST-Pol alpha /primase complex in a recruitment state. Nat.Struct.Mol.Biol., 29, 2022
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3CQ8
| Ternary complex of the L415F mutant RB69 exo(-)polymerase | 分子名称: | CALCIUM ION, DNA (5'-D(*DAP*DCP*DAP*DGP*DGP*DTP*DAP*DAP*DGP*DCP*DAP*DGP*DTP*DCP*DCP*DGP*DCP*DG)-3'), DNA (5'-D(*DGP*DCP*DGP*DGP*DAP*DCP*DTP*DGP*DCP*DTP*DTP*DAP*DCP*DC)-3'), ... | 著者 | Zhong, X, Pedersen, L.C, Kunkel, T.A. | 登録日 | 2008-04-02 | 公開日 | 2008-09-02 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Characterization of a replicative DNA polymerase mutant with reduced fidelity and increased translesion synthesis capacity. Nucleic Acids Res., 36, 2008
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7TQW
| Kod RSGA incorporating PMT, n+2 | 分子名称: | DNA polymerase, Primer, Template | 著者 | Hajjar, M, Chim, N, Chaput, J.C. | 登録日 | 2022-01-27 | 公開日 | 2022-08-31 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.01 Å) | 主引用文献 | Crystallographic analysis of engineered polymerases synthesizing phosphonomethylthreosyl nucleic acid. Nucleic Acids Res., 50, 2022
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3CFP
| Structure of the replicating complex of a POL Alpha family DNA Polymerase, ternary complex 1 | 分子名称: | CALCIUM ION, CHLORIDE ION, DNA (5'-D(*DAP*DCP*DAP*DGP*DGP*DTP*DAP*DAP*DGP*DCP*DAP*DGP*DTP*DCP*DCP*DGP*DCP*DG)-3'), ... | 著者 | Wang, J, Klimenko, D, Wang, M, Steitz, T.A, Konigsberg, W.H. | 登録日 | 2008-03-04 | 公開日 | 2009-03-10 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Insights into base selectivity from the structures
of an RB69 DNA Polymerase triple mutant To be Published
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7UY7
| Tetrahymena CST with Polymerase alpha-Primase | 分子名称: | DNA polymerase, Telomerase associated protein p50, Telomerase-associated protein of 19 kDa, ... | 著者 | He, Y, Song, H, Chan, H, Wang, Y, Liu, B, Susac, L, Zhou, Z.H, Feigon, J. | 登録日 | 2022-05-06 | 公開日 | 2022-07-13 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Structure of Tetrahymena telomerase-bound CST with polymerase alpha-primase. Nature, 608, 2022
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7UY8
| Tetrahymena Polymerase alpha-Primase | 分子名称: | DNA polymerase, DNA polymerase alpha subunit B, DNA primase, ... | 著者 | He, Y, Song, H, Chan, H, Wang, Y, Liu, B, Susac, L, Zhou, Z.H, Feigon, J. | 登録日 | 2022-05-06 | 公開日 | 2022-07-13 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Structure of Tetrahymena telomerase-bound CST with polymerase alpha-primase. Nature, 608, 2022
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3CFO
| Triple Mutant APO structure | 分子名称: | DNA polymerase, GUANOSINE, SULFATE ION | 著者 | Wang, J, Klimenko, D, Wang, M, Steitz, T.A, Konigsberg, W.H. | 登録日 | 2008-03-04 | 公開日 | 2009-03-10 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Insights into base selectivity from the structures
of an RB69 DNA Polymerase triple mutant To be Published
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8B9B
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8B9A
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8B9C
| S. cerevisiae pol alpha - replisome complex | 分子名称: | Cell division control protein 45, Chromosome segregation in meiosis protein 3, DNA polymerase alpha catalytic subunit A, ... | 著者 | Jones, M.L, Yeeles, J.T.P. | 登録日 | 2022-10-05 | 公開日 | 2023-08-09 | 最終更新日 | 2023-08-30 | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | 主引用文献 | How Pol alpha-primase is targeted to replisomes to prime eukaryotic DNA replication. Mol.Cell, 83, 2023
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8B9D
| Human replisome bound by Pol Alpha | 分子名称: | Cell division control protein 45 homolog, Claspin, DNA Molecule, ... | 著者 | Jones, M.L, Yeeles, J.T.P. | 登録日 | 2022-10-05 | 公開日 | 2023-08-09 | 最終更新日 | 2023-08-30 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | How Pol alpha-primase is targeted to replisomes to prime eukaryotic DNA replication. Mol.Cell, 83, 2023
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3CFR
| Structure of the replicating complex of a POL Alpha family DNA Polymerase, ternary complex 2 | 分子名称: | CALCIUM ION, CHLORIDE ION, DNA (5'-D(*DGP*DCP*DGP*DGP*DAP*DCP*DTP*DGP*DCP*DTP*DTP*DAP*(DOC))-3'), ... | 著者 | Wang, J, Klimenko, D, Wang, M, Steitz, T.A, Konigsberg, W.H. | 登録日 | 2008-03-04 | 公開日 | 2009-03-10 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Insights into base selectivity from the structures
of an RB69 DNA Polymerase triple mutant To be Published
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6V93
| Structure of DNA Polymerase Zeta/DNA/dNTP Ternary Complex | 分子名称: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA, ... | 著者 | Malik, R, Kopylov, M, Jain, R, Ubarrextena-Belandia, I, Aggarwal, A.K. | 登録日 | 2019-12-13 | 公開日 | 2020-08-19 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structure and mechanism of B-family DNA polymerase zeta specialized for translesion DNA synthesis. Nat.Struct.Mol.Biol., 27, 2020
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6V8P
| Structure of DNA Polymerase Zeta (Apo) | 分子名称: | DNA polymerase delta small subunit, DNA polymerase delta subunit 3, DNA polymerase zeta catalytic subunit, ... | 著者 | Malik, R, Gomez-Llorente, Y, Ubarretxena-Belandia, I, Aggarwal, A.K. | 登録日 | 2019-12-11 | 公開日 | 2020-08-19 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structure and mechanism of B-family DNA polymerase zeta specialized for translesion DNA synthesis. Nat.Struct.Mol.Biol., 27, 2020
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5VU5
| TNA polymerase, apo | 分子名称: | DNA polymerase | 著者 | Chim, N, Chaput, J.C. | 登録日 | 2017-05-18 | 公開日 | 2017-12-06 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural basis for TNA synthesis by an engineered TNA polymerase. Nat Commun, 8, 2017
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5VU7
| TNA polymerase, open ternary complex | 分子名称: | 5-(6-AMINO-9H-PURIN-9-YL)-4-HYDROXYTETRAHYDROFURAN-3-YL DIHYDROGEN PHOSPHATE, DNA polymerase, DNA template, ... | 著者 | Chim, N, Chaput, J.C. | 登録日 | 2017-05-18 | 公開日 | 2017-12-06 | 最終更新日 | 2017-12-13 | 実験手法 | X-RAY DIFFRACTION (2.72 Å) | 主引用文献 | Structural basis for TNA synthesis by an engineered TNA polymerase. Nat Commun, 8, 2017
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5VU8
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5VU6
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2P5O
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1Q8I
| Crystal structure of ESCHERICHIA coli DNA Polymerase II | 分子名称: | DNA polymerase II | 著者 | Brunzelle, J.S, Muchmore, C.R.A, Mashhoon, N, Blair-Johnson, M, Shuvalova, L, Goodman, M.F, Anderson, W.F, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2003-08-21 | 公開日 | 2004-01-27 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structure of Escherichia Coli DNA Polymerase II To be Published
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2P5G
| Crystal structure of RB69 gp43 in complex with DNA with dAMP opposite an abasic site analog in a 21mer template | 分子名称: | DNA polymerase, Primer DNA, Template DNA | 著者 | Zahn, K.E, Belrhali, H, Wallace, S.S, Doublie, S. | 登録日 | 2007-03-15 | 公開日 | 2007-10-23 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Caught bending the a-rule: crystal structures of translesion DNA synthesis with a non-natural nucleotide. Biochemistry, 46, 2007
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6WJV
| Structure of the Saccharomyces cerevisiae polymerase epsilon holoenzyme | 分子名称: | DNA polymerase epsilon catalytic subunit A, DNA polymerase epsilon subunit B, DNA polymerase epsilon subunit C, ... | 著者 | Yuan, Z, Georgescu, R, Schauer, G.D, O'Donnell, M, Li, H. | 登録日 | 2020-04-14 | 公開日 | 2020-07-08 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structure of the polymerase epsilon holoenzyme and atomic model of the leading strand replisome. Nat Commun, 11, 2020
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1QHT
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