3CFR

Structure of the replicating complex of a POL Alpha family DNA Polymerase, ternary complex 2

Summary for 3CFR

Related1IH7 1IG9 3CFO 3CFP
DescriptorDNA (5'-D(*DTP*DCP*DAP*DAP*DGP*DTP*DAP*DAP*DGP*DCP*DAP*DGP*DTP*DCP*DCP*DGP*DCP*DG)-3'), DNA (5'-D(*DGP*DCP*DGP*DGP*DAP*DCP*DTP*DGP*DCP*DTP*DTP*DAP*(DOC))-3'), DNA polymerase, ... (7 entities in total)
Functional Keywordsdna polymerase, catalytic complex, fidelity, two metal ion mechanism, transferase-dna complex, transferase/dna
Biological sourceBACTERIOPHAGE RB69
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Total number of polymer chains3
Total molecular weight115603.04
Authors
Wang, J.,Klimenko, D.,Wang, M.,Steitz, T.A.,Konigsberg, W.H. (deposition date: 2008-03-04, release date: 2009-03-10, Last modification date: 2011-07-13)
Primary citation
Klimenko, D.,Wang, M.,Steitz, T.A.,Konigsberg, W.H.,Wang, J.
Insights into base selectivity from the structures of an RB69 DNA Polymerase triple mutant
To be Published,
Experimental method
X-RAY DIFFRACTION (2.4 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.27071.0%5.7%1.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 3cfr
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Molmil generated image of 3cfr
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Molmil generated image of 3cfr
rotated about y axis by 90°