3CFR

Structure of the replicating complex of a POL Alpha family DNA Polymerase, ternary complex 2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (T)	DNA (5'-D(*DTP*DCP*DAP*DAP*DGP*DTP*DAP*DAP*DGP*DCP*DAP*DGP*DTP*DCP*DCP*DGP*DCP*DG)-3')	polymer	18	5525.6	1
2	B (P)	DNA (5'-D(*DGP*DCP*DGP*DGP*DAP*DCP*DTP*DGP*DCP*DTP*DTP*DAP*(DOC))-3')	polymer	13	3951.6	1
3	C (A)	DNA polymerase	polymer	909	105407.9	1	UniProt (Q38087) Pfam (PF03104) Pfam (PF00136)	BACTERIOPHAGE RB69	Gp43
4	D, E, F, G, H (A)	CALCIUM ION	non-polymer		40.1	5	Chemie (CA)
5	I (A)	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
6	J (A)	THYMIDINE-5'-TRIPHOSPHATE	non-polymer		482.2	1	Chemie (TTP)
7	K, L, M (T, P, A)	water	water		18.0	629	Chemie (HOH)

Sequence modifications

A: 1 - 903 (UniProt: Q38087)

PDB	External Database	Details
Ala 561	Leu 561	engineered mutation
Gly 565	Ser 565	engineered mutation
Ala 567	Tyr 567	engineered mutation
His 904	-	expression tag
His 905	-	expression tag
His 906	-	expression tag
His 907	-	expression tag
His 908	-	expression tag
His 909	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	114885.0
Non-Polymers*	Number of molecules	7
	Total formula weight	718.0
All*	Total formula weight	115603.0

*Water molecules are not included.