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PDB: 318 件
6B0P
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BU of 6b0p by Molmil
Zinc finger Domain of WT1(-KTS form) with 12+1mer Oligonucleotide with 3' Triplet GGT
分子名称: 1,2-ETHANEDIOL, DNA (5'-D(P*AP*CP*CP*CP*TP*CP*CP*CP*AP*CP*GP*C)-3'), DNA (5'-D(P*GP*CP*GP*TP*GP*GP*GP*AP*GP*GP*GP*T)-3'), ...
著者Horton, J.R, Cheng, X.
登録日2017-09-14
公開日2018-01-03
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.077 Å)
主引用文献Role for first zinc finger of WT1 in DNA sequence specificity: Denys-Drash syndrome-associated WT1 mutant in ZF1 enhances affinity for a subset of WT1 binding sites.
Nucleic Acids Res., 46, 2018
6B0R
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BU of 6b0r by Molmil
Zinc finger Domain of WT1(-KTS form) with M342R Mutation and 14+1mer Oligonucleotide with 3' Triplet TGG
分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*AP*GP*CP*GP*TP*GP*GP*GP*AP*GP*GP*GP*TP*TP*A)-3'), DNA (5'-D(P*TP*AP*AP*CP*CP*CP*TP*CP*CP*CP*AP*CP*GP*C)-3'), ...
著者Horton, J.R, Cheng, X.
登録日2017-09-14
公開日2018-01-03
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.818 Å)
主引用文献Role for first zinc finger of WT1 in DNA sequence specificity: Denys-Drash syndrome-associated WT1 mutant in ZF1 enhances affinity for a subset of WT1 binding sites.
Nucleic Acids Res., 46, 2018
7N5S
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BU of 7n5s by Molmil
ZBTB7A Zinc Finger Domain Bound to -200 Site of Fetal Globin Promoter (Oligo 6)
分子名称: DNA Strand I, DNA Strand II, ZINC ION, ...
著者Horton, J.R, Ren, R, Cheng, X.
登録日2021-06-06
公開日2021-08-25
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.86 Å)
主引用文献Structural basis for human ZBTB7A action at the fetal globin promoter.
Cell Rep, 36, 2021
7N5T
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BU of 7n5t by Molmil
ZBTB7A Zinc Finger Domain Bound to -200 Site of Fetal Globin Promoter (Oligo 5)
分子名称: DNA Strand I, DNA Strand II, ZINC ION, ...
著者Horton, J.R, Ren, R, Cheng, X.
登録日2021-06-06
公開日2021-08-25
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural basis for human ZBTB7A action at the fetal globin promoter.
Cell Rep, 36, 2021
7N5U
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BU of 7n5u by Molmil
ZBTB7A Zinc Finger Domain Bound to DNA Duplex Containing GGACCC (Oligo 21)
分子名称: DNA Strain II, DNA Strand I, ZINC ION, ...
著者Horton, J.R, Ren, R, Cheng, X.
登録日2021-06-06
公開日2022-06-08
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.86 Å)
主引用文献Structural basis for transcription factor ZBTB7A recognition of DNA and effects of ZBTB7A somatic mutations that occur in human acute myeloid leukemia.
J.Biol.Chem., 299, 2023
7N5W
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BU of 7n5w by Molmil
ZBTB7A Zinc Finger Domain Bound to DNA Duplex Containing GGACCC (Oligo 23)
分子名称: 1,2-ETHANEDIOL, DNA Strand I, DNA Strand II, ...
著者Horton, J.R, Ren, R, Cheng, X.
登録日2021-06-06
公開日2022-06-08
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Structural basis for transcription factor ZBTB7A recognition of DNA and effects of ZBTB7A somatic mutations that occur in human acute myeloid leukemia.
J.Biol.Chem., 299, 2023
7N5V
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BU of 7n5v by Molmil
ZBTB7A Zinc Finger Domain Bound to DNA Duplex Containing GGACCC (Oligo 20)
分子名称: DNA Strand I, DNA Strand II, ZINC ION, ...
著者Horton, J.R, Ren, R, Cheng, X.
登録日2021-06-06
公開日2022-06-08
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.08 Å)
主引用文献Structural basis for transcription factor ZBTB7A recognition of DNA and effects of ZBTB7A somatic mutations that occur in human acute myeloid leukemia.
J.Biol.Chem., 299, 2023
7MC3
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BU of 7mc3 by Molmil
Solution structure of Miz-1 zinc finger 12
分子名称: Isoform 2 of Zinc finger and BTB domain-containing protein 17, ZINC ION
著者Boisvert, O, Lavigne, P.
登録日2021-04-01
公開日2021-04-21
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Zinc Fingers 10 and 11 of Miz-1 undergo conformational exchange to achieve specific DNA binding.
Structure, 30, 2022
7MC1
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BU of 7mc1 by Molmil
Solution structure of Miz-1 Zinc finger 10
分子名称: Isoform 2 of Zinc finger and BTB domain-containing protein 17, ZINC ION
著者Boisvert, O, Lavigne, P.
登録日2021-04-01
公開日2021-04-28
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Zinc Fingers 10 and 11 of Miz-1 undergo conformational exchange to achieve specific DNA binding.
Structure, 30, 2022
7MC2
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BU of 7mc2 by Molmil
Solution structure of Miz-1 Zinc finger 11 H586Y
分子名称: Isoform 2 of Zinc finger and BTB domain-containing protein 17, ZINC ION
著者Boisvert, O, Lavigne, P.
登録日2021-04-01
公開日2021-04-28
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Zinc Fingers 10 and 11 of Miz-1 undergo conformational exchange to achieve specific DNA binding.
Structure, 30, 2022
5K5L
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BU of 5k5l by Molmil
Homo sapiens CCCTC-binding factor (CTCF) ZnF6-8 and H19 sequence DNA complex structure
分子名称: DNA (5'-D(*GP*TP*TP*GP*CP*CP*GP*CP*GP*TP*G)-3'), DNA (5'-D(P*AP*CP*GP*CP*GP*GP*CP*AP*AP*C)-3'), Transcriptional repressor CTCF, ...
著者Hashimoto, H, Cheng, X.
登録日2016-05-23
公開日2017-05-24
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.125 Å)
主引用文献Structural Basis for the Versatile and Methylation-Dependent Binding of CTCF to DNA.
Mol. Cell, 66, 2017
5K5H
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BU of 5k5h by Molmil
Homo sapiens CCCTC-binding factor (CTCF) ZnF4-7 and DNA complex structure
分子名称: DNA (5'-D(*CP*AP*GP*CP*AP*GP*GP*GP*GP*GP*CP*GP*C)-3'), DNA (5'-D(*CP*GP*CP*CP*CP*CP*CP*TP*GP*CP*TP*GP*G)-3'), Transcriptional repressor CTCF, ...
著者Hashimoto, H, Cheng, X.
登録日2016-05-23
公開日2017-05-24
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.108 Å)
主引用文献Structural Basis for the Versatile and Methylation-Dependent Binding of CTCF to DNA.
Mol. Cell, 66, 2017
1U86
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BU of 1u86 by Molmil
321-TW-322 insertion mutant of the third zinc finger of BKLF
分子名称: Kruppel-like factor 3, ZINC ION
著者Cram, E.D, Mackay, J.P, Matthews, J.M.
登録日2004-08-05
公開日2005-08-23
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structures of tryptophan-containing CCHH zinc finger mutants
To be Published
5KE8
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BU of 5ke8 by Molmil
mouse Klf4 E446P ZnF1-3 and MpG/MpG sequence DNA complex structure
分子名称: DNA (5'-D(*GP*AP*GP*GP*(5CM)P*GP*TP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*AP*(5CM)P*GP*CP*CP*TP*C)-3'), Krueppel-like factor 4, ...
著者Hashimoto, H, Cheng, X.
登録日2016-06-09
公開日2016-09-14
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Distinctive Klf4 mutants determine preference for DNA methylation status.
Nucleic Acids Res., 44, 2016
5K5J
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BU of 5k5j by Molmil
Homo sapiens CCCTC-binding factor (CTCF) ZnF5-8 and DNA complex structure in space group P41212
分子名称: ACETATE ION, DNA (5'-D(*CP*CP*CP*TP*GP*CP*TP*GP*GP*CP*AP*AP*C)-3'), DNA (5'-D(*TP*TP*GP*CP*CP*AP*GP*CP*AP*GP*GP*GP*G)-3'), ...
著者Hashimoto, H, Cheng, X.
登録日2016-05-23
公開日2017-05-24
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.287 Å)
主引用文献Structural Basis for the Versatile and Methylation-Dependent Binding of CTCF to DNA.
Mol. Cell, 66, 2017
5KE9
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BU of 5ke9 by Molmil
mouse Klf4 E446P ZnF1-3 and TpG/CpA sequence DNA complex structure
分子名称: DNA (5'-D(*GP*AP*GP*GP*TP*GP*TP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*AP*CP*AP*CP*CP*TP*C)-3'), Krueppel-like factor 4, ...
著者Hashimoto, H, Cheng, X.
登録日2016-06-09
公開日2016-09-14
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.336 Å)
主引用文献Distinctive Klf4 mutants determine preference for DNA methylation status.
Nucleic Acids Res., 44, 2016
5KEA
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BU of 5kea by Molmil
mouse Klf4 ZnF1-3 (E446D) and CpG/CpG sequence DNA complex structure: Form I
分子名称: DNA (5'-D(*GP*AP*GP*GP*CP*GP*TP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*AP*CP*GP*CP*CP*TP*C)-3'), Krueppel-like factor 4, ...
著者Hashimoto, H, Cheng, X.
登録日2016-06-09
公開日2016-09-14
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.458 Å)
主引用文献Distinctive Klf4 mutants determine preference for DNA methylation status.
Nucleic Acids Res., 44, 2016
5KL6
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BU of 5kl6 by Molmil
Wilms Tumor Protein (WT1) Q369R ZnF2-4 in complex with DNA
分子名称: DNA (5'-D(*AP*GP*CP*GP*TP*GP*GP*GP*GP*GP*T)-3'), DNA (5'-D(*TP*AP*CP*CP*CP*CP*CP*AP*CP*GP*C)-3'), Wilms tumor protein, ...
著者Hashimoto, H, Cheng, X.
登録日2016-06-23
公開日2016-09-14
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.641 Å)
主引用文献Denys-Drash syndrome associated WT1 glutamine 369 mutants have altered sequence-preferences and altered responses to epigenetic modifications.
Nucleic Acids Res., 44, 2016
5KL4
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BU of 5kl4 by Molmil
Wilms Tumor Protein (WT1) ZnF2-4 Q369H in complex with formylated DNA
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*GP*GP*GP*(5FC)P*GP*T)-3'), ...
著者Hashimoto, H, Cheng, X.
登録日2016-06-23
公開日2016-09-14
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.783 Å)
主引用文献Denys-Drash syndrome associated WT1 glutamine 369 mutants have altered sequence-preferences and altered responses to epigenetic modifications.
Nucleic Acids Res., 44, 2016
5KKQ
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BU of 5kkq by Molmil
Homo sapiens CCCTC-binding factor (CTCF) ZnF3-7 and DNA complex structure
分子名称: DNA (5'-D(*GP*CP*CP*AP*GP*CP*AP*GP*GP*GP*GP*GP*CP*GP*CP*TP*A)-3'), DNA (5'-D(*TP*AP*GP*CP*GP*CP*CP*CP*CP*CP*TP*GP*CP*TP*GP*GP*C)-3'), Transcriptional repressor CTCF, ...
著者Hashimoto, H, Wang, D, Cheng, X.
登録日2016-06-22
公開日2017-05-24
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.744 Å)
主引用文献Structural Basis for the Versatile and Methylation-Dependent Binding of CTCF to DNA.
Mol. Cell, 66, 2017
5KL5
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BU of 5kl5 by Molmil
Wilms Tumor Protein (WT1) ZnF2-4 Q369H in complex with carboxylated DNA
分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*AP*GP*CP*GP*TP*GP*GP*GP*(1CC)P*GP*T)-3'), DNA (5'-D(*TP*AP*(5CM)P*GP*CP*CP*CP*AP*CP*GP*C)-3'), ...
著者Hashimoto, H, Cheng, X.
登録日2016-06-23
公開日2016-09-14
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.289 Å)
主引用文献Denys-Drash syndrome associated WT1 glutamine 369 mutants have altered sequence-preferences and altered responses to epigenetic modifications.
Nucleic Acids Res., 44, 2016
5KL2
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BU of 5kl2 by Molmil
Wilms Tumor Protein (WT1) ZnF2-4 in complex with DNA
分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*AP*GP*CP*GP*TP*GP*GP*GP*AP*GP*T)-3'), DNA (5'-D(*TP*AP*CP*TP*CP*CP*CP*AP*CP*GP*C)-3'), ...
著者Hashimoto, H, Cheng, X.
登録日2016-06-23
公開日2016-09-14
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.692 Å)
主引用文献Denys-Drash syndrome associated WT1 glutamine 369 mutants have altered sequence-preferences and altered responses to epigenetic modifications.
Nucleic Acids Res., 44, 2016
8SSU
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BU of 8ssu by Molmil
ZnFs 3-11 of CCCTC-binding factor (CTCF) Complexed with 19mer DNA
分子名称: 1,2-ETHANEDIOL, DNA (19-MER) Strand I, DNA (19-MER) Strand II, ...
著者Horton, J.R, Yang, J, Cheng, X.
登録日2023-05-08
公開日2023-08-02
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.89 Å)
主引用文献Structures of CTCF-DNA complexes including all 11 zinc fingers.
Nucleic Acids Res., 51, 2023
8SST
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BU of 8sst by Molmil
ZnFs 1-7 of CCCTC-binding factor (CTCF) K365T Mutant Complexed with 23mer
分子名称: 1,2-ETHANEDIOL, DNA Strand (23mer) I, DNA Strand (23mer) II, ...
著者Horton, J.R, Yang, J, Cheng, X.
登録日2023-05-08
公開日2023-08-02
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Structures of CTCF-DNA complexes including all 11 zinc fingers.
Nucleic Acids Res., 51, 2023
8SSS
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BU of 8sss by Molmil
ZnFs 1-7 of CCCTC-binding factor (CTCF) Complexed with 23mer
分子名称: 1,2-ETHANEDIOL, DNA Strand (23mer) I, DNA Strand (23mer) II, ...
著者Horton, J.R, Yang, J, Cheng, X.
登録日2023-05-08
公開日2023-08-02
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structures of CTCF-DNA complexes including all 11 zinc fingers.
Nucleic Acids Res., 51, 2023

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