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PDB: 256 件
2B4X
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Crystal Structure of Antithrombin-III
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antithrombin-III
著者Adams, T.E, Huntington, J.A, Johnson, D.J.D, Bock, S.C.
登録日2005-09-27
公開日2006-10-10
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal Structure of Antithrombin-III
To be Published
2ANT
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THE 2.6 A STRUCTURE OF ANTITHROMBIN INDICATES A CONFORMATIONAL CHANGE AT THE HEPARIN BINDING SITE
分子名称: 2-acetamido-2-deoxy-beta-D-allopyranose, ANTITHROMBIN
著者Skinner, R, Abrahams, J.-P, Whisstock, J.C, Lesk, A.M, Carrell, R.W, Wardell, M.R.
登録日1997-01-28
公開日1997-06-16
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The 2.6 A structure of antithrombin indicates a conformational change at the heparin binding site.
J.Mol.Biol., 266, 1997
2ARQ
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Human plasminogen activator inhibitor-2.[loop (66-98) deletion mutant] complexed with peptide n-acetyl-teaaagdggvmtgr-oh
分子名称: 14-mer from Plasminogen activator inhibitor-2, Plasminogen activator inhibitor-2
著者Di Giusto, D.A, Sutherland, A.P, Jankova, L, Harrop, S.J, Curmi, P.M, King, G.C.
登録日2005-08-21
公開日2006-07-11
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Plasminogen activator inhibitor-2 is highly tolerant to P8 residue substitution--implications for serpin mechanistic model and prediction of nsSNP activities
J.Mol.Biol., 353, 2005
1LQ8
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Crystal structure of cleaved protein C inhibitor
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Huntington, J.A, Kjellberg, M, Stenflo, J.
登録日2002-05-09
公開日2003-02-11
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structure of Protein C Inhibitor Provides Insights into Hormone Binding and Heparin Activation
Structure, 11, 2003
1MTP
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The X-ray crystal structure of a serpin from a thermophilic prokaryote
分子名称: Serine Proteinase Inhibitor (SERPIN), Chain A, Chain B
著者Irving, J.A, Cabrita, L.D, Rossjohn, J, Pike, R.N, Bottomley, S.P, Whisstock, J.C.
登録日2002-09-21
公開日2003-04-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The 1.5 A crystal structure of a prokaryote serpin: controlling conformational change in a heated environment
Structure, 11, 2003
2BEH
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Crystal structure of antithrombin variant S137A/V317C/T401C with plasma latent antithrombin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antithrombin-III, ...
著者Johnson, D.J, Luis, S.A, Huntington, J.A.
登録日2005-10-24
公開日2005-11-01
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of monomeric native antithrombin reveals a novel reactive center loop conformation.
J.Biol.Chem., 281, 2006
1NQ9
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Crystal Structure of Antithrombin in the Pentasaccharide-Bound Intermediate State
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3,4-di-O-methyl-2,6-di-O-sulfo-alpha-D-glucopyranose-(1-4)-2,3-di-O-methyl-beta-D-glucopyranuronic acid-(1-4)-2,3,6-tri-O-sulfo-alpha-D-glucopyranose-(1-4)-3-O-methyl-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-methyl 2,3,6-tri-O-sulfo-alpha-D-glucopyranoside, ...
著者Huntington, J.A, Johnson, D.J.D.
登録日2003-01-21
公開日2003-09-30
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal Structure of Antithrombin in a Heparin-Bound Intermediate State
Biochemistry, 42, 2003
1KCT
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ALPHA1-ANTITRYPSIN
分子名称: ALPHA1-ANTITRYPSIN
著者Song, H.K, Suh, S.W.
登録日1996-08-06
公開日1997-01-11
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3.46 Å)
主引用文献Crystal structure of an uncleaved alpha 1-antitrypsin reveals the conformation of its inhibitory reactive loop.
FEBS Lett., 377, 1995
2DUT
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Crystal structure of a M-loop deletion variant of MENT in the native conformation
分子名称: Heterochromatin-associated protein MENT
著者Whisstock, J.C, Buckle, A.M, McGowan, S, Irving, J.A.
登録日2006-07-26
公開日2006-08-08
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献X-ray crystal structure of MENT: evidence for functional loop-sheet polymers in chromatin condensation
Embo J., 25, 2006
2CEO
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thyroxine-binding globulin complex with thyroxine
分子名称: 3,5,3',5'-TETRAIODO-L-THYRONINE, GLYCEROL, THYROXINE-BINDING GLOBULIN
著者Zhou, A, Wei, Z, Read, R.J, Carrell, R.W.
登録日2006-02-08
公開日2006-08-14
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Mechanism for the Carriage and Release of Thyroxine in the Blood.
Proc.Natl.Acad.Sci.USA, 103, 2006
2H4R
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Crystal structure of wildtype MENT in the native conformation
分子名称: Heterochromatin-associated protein MENT
著者Irving, J.A, Whisstock, J.C, Buckle, A.M, McGowan, S.
登録日2006-05-25
公開日2006-07-18
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献X-ray crystal structure of MENT: evidence for functional loop-sheet polymers in chromatin condensation.
Embo J., 25, 2006
2H4Q
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Crystal structure of a M-loop deletion variant of MENT in the cleaved conformation
分子名称: Heterochromatin-associated protein MENT
著者Whisstock, J.C, Buckle, A.M, McGowan, S, Irving, J.A.
登録日2006-05-25
公開日2006-07-18
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献X-ray crystal structure of MENT: evidence for functional loop-sheet polymers in chromatin condensation.
Embo J., 25, 2006
2H4P
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Crystal structure of wildtype MENT in the cleaved conformation
分子名称: Heterochromatin-associated protein MENT
著者Buckle, A.M, McGowan, S, Irving, J.A, Whisstock, J.C.
登録日2006-05-24
公開日2006-07-18
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献X-ray crystal structure of MENT: evidence for functional loop-sheet polymers in chromatin condensation.
Embo J., 25, 2006
2HI9
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Crystal Structure of human native protein C inhibitor
分子名称: CITRIC ACID, GLYCEROL, Plasma serine protease inhibitor
著者Li, W, Adams, T.E, Huntington, J.A.
登録日2006-06-29
公開日2007-03-13
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of native protein C inhibitor provides insight into its multiple functions.
J.Biol.Chem., 282, 2007
2HIJ
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Crystal Structure of P14 Alanine Variant of Antithrombin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antithrombin-III, ...
著者Luis, S.A, Bock, S.C, Huntington, J.A.
登録日2006-06-29
公開日2007-06-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal Structure of P14 Alanine Variant of Antithrombin
To be Published
1F0C
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STRUCTURE OF THE VIRAL SERPIN CRMA
分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, ICE INHIBITOR
著者Renatus, M, Zhou, Q, Stennicke, H.R, Snipas, S.J, Turk, D, Bankston, L.A, Liddington, R.C, Salvesen, G.S.
登録日2000-05-15
公開日2000-09-06
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Crystal structure of the apoptotic suppressor CrmA in its cleaved form.
Structure Fold.Des., 8, 2000
3CAA
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CLEAVED ANTICHYMOTRYPSIN A347R
分子名称: ANTICHYMOTRYPSIN
著者Lukacs, C.M, Christianson, D.W.
登録日1997-08-18
公開日1998-02-25
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Engineering an anion-binding cavity in antichymotrypsin modulates the "spring-loaded" serpin-protease interaction.
Biochemistry, 37, 1998
3CVM
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High resolution structure of a stable Plasminogen activator inhibitor type-1 in its protease cleaved form
分子名称: Plasminogen activator inhibitor 1
著者Jensen, J.K, Gettins, P.G.W.
登録日2008-04-18
公開日2008-08-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献High-resolution structure of the stable plasminogen activator inhibitor type-1 variant 14-1B in its proteinase-cleaved form: a new tool for detailed interaction studies and modeling.
Protein Sci., 17, 2008
3CWM
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Crystal structure of alpha-1-antitrypsin complexed with citrate
分子名称: Alpha-1-antitrypsin, CITRIC ACID
著者Morton, C.J, Hansen, G, Feil, S.C, Adams, J.J, Parker, M.W.
登録日2008-04-22
公開日2008-09-23
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Preventing serpin aggregation: The molecular mechanism of citrate action upon antitrypsin unfolding.
Protein Sci., 17, 2008
1HP7
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A 2.1 ANGSTROM STRUCTURE OF AN UNCLEAVED ALPHA-1-ANTITRYPSIN SHOWS VARIABILITY OF THE REACTIVE CENTER AND OTHER LOOPS
分子名称: ALPHA-1-ANTITRYPSIN, BETA-MERCAPTOETHANOL, ZINC ION
著者Kim, S.-J, Woo, J.-R, Seo, E.J, Yu, M.-H, Ryu, S.-E.
登録日2000-12-12
公開日2001-03-14
最終更新日2021-11-10
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A 2.1 A resolution structure of an uncleaved alpha(1)-antitrypsin shows variability of the reactive center and other loops.
J.Mol.Biol., 306, 2001
1HLE
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CRYSTAL STRUCTURE OF CLEAVED EQUINE LEUCOCYTE ELASTASE INHIBITOR DETERMINED AT 1.95 ANGSTROMS RESOLUTION
分子名称: CALCIUM ION, HORSE LEUKOCYTE ELASTASE INHIBITOR
著者Baumann, U, Bode, W, Huber, R, Travis, J, Potempa, J.
登録日1992-04-13
公開日1994-01-31
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structure of cleaved equine leucocyte elastase inhibitor determined at 1.95 A resolution.
J.Mol.Biol., 226, 1992
3DRU
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Crystal Structure of Gly117Phe Alpha1-Antitrypsin
分子名称: Alpha-1-antitrypsin
著者Gooptu, B, Nobeli, I, Purkiss, A, Phillips, R.L, Mallya, M, Lomas, D.A, Barrett, T.E.
登録日2008-07-11
公開日2009-03-31
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystallographic and cellular characterisation of two mechanisms stabilising the native fold of alpha1-antitrypsin: implications for disease and drug design.
J.Mol.Biol., 387, 2009
3DRM
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2.2 Angstrom Crystal Structure of Thr114Phe Alpha1-Antitrypsin
分子名称: Alpha-1-antitrypsin
著者Gooptu, B, Nobeli, I, Purkiss, A, Phillips, R.L, Mallya, M, Lomas, D.A, Barrett, T.E.
登録日2008-07-11
公開日2009-03-31
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystallographic and cellular characterisation of two mechanisms stabilising the native fold of alpha1-antitrypsin: implications for disease and drug design.
J.Mol.Biol., 387, 2009
3DLW
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Antichymotrypsin
分子名称: Alpha-1-antichymotrypsin
著者Feil, S.C.
登録日2008-06-29
公開日2009-07-07
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Identification and characterization of a misfolded monomeric serpin formed at physiological temperature
J.Mol.Biol., 403, 2010
3CWL
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Crystal structure of alpha-1-antitrypsin, crystal form B
分子名称: Alpha-1-antitrypsin, CHLORIDE ION
著者Morton, C.J, Hansen, G, Feil, S.C, Adams, J.J, Parker, M.W.
登録日2008-04-22
公開日2008-09-23
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献Preventing serpin aggregation: The molecular mechanism of citrate action upon antitrypsin unfolding.
Protein Sci., 17, 2008

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