2BEH

Crystal structure of antithrombin variant S137A/V317C/T401C with plasma latent antithrombin

Summary for 2BEH

• Entry DOI: 10.2210/pdb2beh/pdb
• Related: 1T1F 1TB6 2B5T
• Descriptor: Antithrombin-III, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• Functional Keywords: antithrombin dimer, blood clotting
• Biological source: Homo sapiens (human); More
• Cellular location: Secreted, extracellular space: P01008 P01008
• Total number of polymer chains: 2
• Total formula weight: 100161.94

Authors

Johnson, D.J.,Luis, S.A.,Huntington, J.A. (deposition date: 2005-10-24, release date: 2005-11-01, Last modification date: 2021-10-20)

• Primary citation: Johnson, D.J.,Langdown, J.,Li, W.,Luis, S.A.,Baglin, T.P.,Huntington, J.A.; Crystal structure of monomeric native antithrombin reveals a novel reactive center loop conformation.; J.Biol.Chem., 281:35478-35486, 2006; PubMed: 16973611; DOI: 10.1074/jbc.M607204200

Experimental method

X-RAY DIFFRACTION (2.7 Å)