2B5T
2.1 Angstrom structure of a nonproductive complex between antithrombin, synthetic heparin mimetic SR123781 and two S195A thrombin molecules
Summary for 2B5T
Entry DOI | 10.2210/pdb2b5t/pdb |
Related | 1NQ9 1T1F 1TB6 |
Descriptor | Thrombin, 2-acetamido-2-deoxy-beta-D-glucopyranose, Antithrombin-III, ... (11 entities in total) |
Functional Keywords | blood coagulation, blood clotting |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 5 |
Total formula weight | 128613.87 |
Authors | Johnson, D.J.,Li, W.,Luis, S.A.,Carrell, R.W.,Huntington, J.A. (deposition date: 2005-09-29, release date: 2006-09-19, Last modification date: 2023-08-23) |
Primary citation | Johnson, D.J.,Langdown, J.,Li, W.,Luis, S.A.,Baglin, T.P.,Huntington, J.A. Crystal structure of monomeric native antithrombin reveals a novel reactive center loop conformation. J.Biol.Chem., 281:35478-35486, 2006 Cited by PubMed: 16973611DOI: 10.1074/jbc.M607204200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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