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PDB: 256 件

5DUQ
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Active human c1-inhibitor in complex with dextran sulfate
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Plasma protease C1 inhibitor, SULFITE ION, ...
著者Dijk, M, Holkers, J, Voskamp, P, Giannetti, B.M, Waterreus, W.J, van Veen, H.A, Pannu, N.S.
登録日2015-09-20
公開日2016-08-31
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献How Dextran Sulfate Affects C1-inhibitor Activity: A Model for Polysaccharide Potentiation.
Structure, 24, 2016
3T1P
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BU of 3t1p by Molmil
Crystal structure of an alpha-1-antitrypsin trimer
分子名称: Alpha-1-antitrypsin
著者Huntington, J.A, Yamasaki, M.
登録日2011-07-22
公開日2011-08-17
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.9 Å)
主引用文献Molecular basis of alpha 1-antitrypsin deficiency revealed by the structure of a domain-swapped trimer.
EMBO Rep., 12, 2011
8GXV
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BU of 8gxv by Molmil
Structure of a bacterial serpin Choloropin derived from Cholorobium limicola
分子名称: GLYCEROL, Proteinase inhibitor I4 serpin, ZINC ION
著者Zhou, A, Xu, J.
登録日2022-09-21
公開日2023-09-27
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Climpin, a Novel Bacterial a Serpin inducing a Broad Range of Proteases and Regulated by Heparin and DNA.
To Be Published
4P0O
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Cleaved Serpin 42Da
分子名称: Serine protease inhibitor 4, isoform B
著者Ellisdon, A.M, Whisstock, J.C.
登録日2014-02-21
公開日2014-05-07
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献High resolution structure of cleaved Serpin 42 Da from Drosophila melanogaster.
Bmc Struct.Biol., 14, 2014
4P0F
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Cleaved Serpin 42Da (C 2 2 21)
分子名称: Serine protease inhibitor 4, isoform B
著者Ellisdon, A.M, Whisstock, J.C.
登録日2014-02-21
公開日2014-05-07
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献High resolution structure of cleaved Serpin 42 Da from Drosophila melanogaster.
Bmc Struct.Biol., 14, 2014
5INW
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BU of 5inw by Molmil
Structure of reaction loop cleaved lamprey angiotensinogen
分子名称: C-terminal peptide of Putative angiotensinogen, Putative angiotensinogen, SULFATE ION
著者Wei, H, Zhou, A.
登録日2016-03-08
公開日2016-10-05
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Heparin Binds Lamprey Angiotensinogen and Promotes Thrombin Inhibition through a Template Mechanism
J.Biol.Chem., 291, 2016
5M3X
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BU of 5m3x by Molmil
Crystal structure of human angiotensin I-deleted angiotensinogen
分子名称: Angiotensinogen
著者Yan, Y, Read, R.J.
登録日2016-10-17
公開日2017-12-20
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.63 Å)
主引用文献Structural basis for the specificity of renin-mediated angiotensinogen cleavage.
J. Biol. Chem., 294, 2019
3STO
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BU of 3sto by Molmil
Serpin from the trematode Schistosoma Haematobium
分子名称: Serine protease inhibitor
著者Granzin, J, Weiergraeber, O.H, Lee, X, Blanton, R.E.
登録日2011-07-11
公開日2012-05-30
最終更新日2013-01-23
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Three-dimensional structure of a schistosome serpin revealing an unusual configuration of the helical subdomain.
Acta Crystallogr.,Sect.D, 68, 2012
5IO1
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BU of 5io1 by Molmil
CRYSTAL STRUCTURE OF RECOMBINANT HUMAN Z ALPHA-1-ANTITRYPSIN
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-1-antitrypsin
著者Zhou, A.
登録日2016-03-08
公開日2016-06-08
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.34 Å)
主引用文献Molecular Mechanism of Z alpha 1-Antitrypsin Deficiency
J. Biol. Chem., 291, 2016
8H4X
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BU of 8h4x by Molmil
Structure of cleaved Serpin B9
分子名称: 1,2-ETHANEDIOL, Serpin B9, ZINC ION
著者Zhou, A, Yan, T.
登録日2022-10-11
公開日2023-10-25
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Expression, purification and crystallization of cleaved Serpin B9
To Be Published
5EI0
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BU of 5ei0 by Molmil
Structure of RCL-cleaved vaspin (serpinA12)
分子名称: Serpin A12
著者Pippel, J, Kuettner, B.E, Ulbricht, D, Daberger, J, Schultz, S, Heiker, J.T, Strater, N.
登録日2015-10-29
公開日2015-11-11
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of cleaved vaspin (serpinA12).
Biol.Chem., 397, 2016
8PI2
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BU of 8pi2 by Molmil
Native alpha-1-antitrypsin at 1.5 Angstrom (Cys232Ser)
分子名称: 1,2-ETHANEDIOL, Alpha-1-antitrypsin, DIMETHYL SULFOXIDE, ...
著者Wang, M, Irving, J.A.
登録日2023-06-20
公開日2023-07-05
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Structural determinants of instability in alpha-1-antitrypsin
To Be Published
5M3Y
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BU of 5m3y by Molmil
Crystal structure of human glycosylated angiotensinogen
分子名称: Angiotensinogen, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Yan, Y, Read, R.J.
登録日2016-10-17
公開日2017-12-20
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for the specificity of renin-mediated angiotensinogen cleavage.
J. Biol. Chem., 294, 2019
3UT3
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BU of 3ut3 by Molmil
A novel PAI-I inhibitor and its structural mechanism
分子名称: 2,5-dihydroxy-3-undecylcyclohexa-2,5-diene-1,4-dione, Plasminogen activator inhibitor 1
著者Lin, Z.H, Hong, Z.B, Shi, X.L, Hu, L.H, Andreasen, P.A, Huang, M.D.
登録日2011-11-25
公開日2013-02-06
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.42 Å)
主引用文献A novel PAI-I inhibitor and its structural mechanism
To be Published
8H55
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BU of 8h55 by Molmil
The structure of zebrafish angiotensinogen
分子名称: Angiotensinogen, SULFATE ION
著者Zhou, A, Wei, H.
登録日2022-10-12
公開日2023-10-18
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献BIOLOGICAL IMPLICATIONS OF A 2 ANGSTROMS STRUCTURE OF DIMERIC ANGIOTENSINOGEN
To Be Published
5NBV
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BU of 5nbv by Molmil
Crystal structure of native alpha-1-antitrypsin with seven stabilising mutations
分子名称: Alpha-1-antitrypsin, GLYCEROL
著者Huntington, J.A, Pomowski, A, Johnson, D.J.D.
登録日2017-03-02
公開日2018-03-21
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献CRYSTAL STRUCTURE OF THE Z VARIANT OF ALPHA-1-ANTITRYPSIN REVEALS STRUCTURAL AND DYNAMICAL CHANGES AND SUPPORTS A C-TERMINAL DOMAIN SWAP MECHANISM OF POLYMERIZATION
To Be Published
8P4U
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BU of 8p4u by Molmil
Alpha-1-antitrypsin - Sydney variant (G192C)
分子名称: Alpha-1-antitrypsin
著者Kamuda, K, Lomas, D.A, Irving, J.A.
登録日2023-05-23
公開日2024-04-03
最終更新日2024-07-17
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献A novel pathological mutant reveals the role of torsional flexibility in the serpin breach in adoption of an aggregation-prone intermediate.
Febs J., 291, 2024
8P4J
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BU of 8p4j by Molmil
Alpha-1-antitrypsin - Sydney variant (G192C)
分子名称: Alpha-1-antitrypsin
著者Kamuda, K, Lomas, D.A, Irving, J.A.
登録日2023-05-22
公開日2024-04-03
最終更新日2024-07-17
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献A novel pathological mutant reveals the role of torsional flexibility in the serpin breach in adoption of an aggregation-prone intermediate.
Febs J., 291, 2024
4PYW
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BU of 4pyw by Molmil
1.92 angstrom crystal structure of A1AT:TTAI ternary complex
分子名称: ACE-THR-THR-ALA-ILE-NH2, Alpha-1-antitrypsin, GLYCEROL
著者Nyon, M.P, Day, J, Gooptu, B.
登録日2014-03-28
公開日2015-06-10
最終更新日2022-08-24
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献An integrative approach combining ion mobility mass spectrometry, X-ray crystallography, and nuclear magnetic resonance spectroscopy to study the conformational dynamics of alpha 1 -antitrypsin upon ligand binding.
Protein Sci., 24, 2015
7BFI
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BU of 7bfi by Molmil
A double-histidine mutant of HSP47 slows down client release at low pH
分子名称: 15R8 collagen model peptide, Collagen-binding protein
著者Oecal, S, Baumann, U.
登録日2021-01-03
公開日2021-11-10
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献Collagen's primary structure determines collagen:HSP47 complex stoichiometry.
J.Biol.Chem., 297, 2021
6CJ7
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BU of 6cj7 by Molmil
Crystal structure of Manduca sexta Serine protease inhibitor (Serpin)-12
分子名称: Serpin-12
著者Gulati, M, Hu, Y, Peng, S, Pathak, P.K, Wang, Y, Deng, J, Jiang, H.
登録日2018-02-26
公開日2018-07-04
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Manduca sexta serpin-12 controls the prophenoloxidase activation system in larval hemolymph.
Insect Biochem. Mol. Biol., 99, 2018
4ZK0
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BU of 4zk0 by Molmil
Psoriasis pathogenesis - Pso p27 constitute a compact structure forming large aggregates. High pH structure
分子名称: Serpin B4, ZINC ION
著者Helland, R, Lysvand, H, Slupphaug, G, Iversen, O.J.
登録日2015-04-29
公開日2015-07-01
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Psoriasis pathogenesis - Pso p27 constitutes a compact structure forming large aggregates.
Biochem Biophys Rep, 2, 2015
4RSQ
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BU of 4rsq by Molmil
2.9A resolution structure of SRPN2 (K198C/E359C) from Anopheles gambiae
分子名称: Serpin 2
著者Lovell, S, Battaile, K.P, Zhang, X, Meekins, D.A, An, C, Michel, K.
登録日2014-11-10
公開日2014-12-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural and Inhibitory Effects of Hinge Loop Mutagenesis in Serpin-2 from the Malaria Vector Anopheles gambiae.
J.Biol.Chem., 290, 2015
4ROA
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1.90A resolution structure of SRPN2 (S358W) from Anopheles gambiae
分子名称: Serpin 2
著者Lovell, S, Battaile, K.P, Zhang, X, Meekins, D.A, An, C, Michel, K.
登録日2014-10-28
公開日2014-12-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural and Inhibitory Effects of Hinge Loop Mutagenesis in Serpin-2 from the Malaria Vector Anopheles gambiae.
J.Biol.Chem., 290, 2015
4ZK3
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Psoriasis pathogenesis - Pso p27 constitute a compact structure forming large aggregates. Low pH structure
分子名称: Serpin B3
著者Helland, R, Lysvand, H, Slupphaug, G, Iversen, O.J.
登録日2015-04-29
公開日2015-07-01
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Psoriasis pathogenesis - Pso p27 constitutes a compact structure forming large aggregates.
Biochem Biophys Rep, 2, 2015

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