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PDB: 549 件

1MML
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MECHANISTIC IMPLICATIONS FROM THE STRUCTURE OF A CATALYTIC FRAGMENT OF MMLV REVERSE TRANSCRIPTASE
分子名称: MMLV REVERSE TRANSCRIPTASE
著者Georgiadis, M.M, Jessen, S.M, Ogata, C.M, Telesnitsky, A, Goff, S.P, Hendrickson, W.A.
登録日1995-07-18
公開日1995-10-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Mechanistic implications from the structure of a catalytic fragment of Moloney murine leukemia virus reverse transcriptase.
Structure, 3, 1995
2FVQ
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A Structural Study of the CA Dinucleotide Step in the Integrase Processing Site of Moloney Murine Leukemia Virus
分子名称: 5'-D(*CP*TP*TP*TP*CP*AP*TP*TP*AP*AP*TP*GP*AP*AP*AP*G)-3', reverse transcriptase
著者Montano, S.P, Cote, M.L, Roth, M.J, Georgiadis, M.M.
登録日2006-01-31
公開日2006-12-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structures of oligonucleotides including the integrase processing site of the Moloney murine leukemia virus.
Nucleic Acids Res., 34, 2006
2FVP
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A Structural Study of the CA Dinucleotide Step in the Integrase Processing Site of Moloney Murine Leukemia Virus
分子名称: 5'-D(*TP*TP*TP*CP*AP*TP*TP*GP*CP*AP*AP*TP*GP*AP*AP*A)-3', Reverse transcriptase
著者Montano, S.P, Cote, M.L, Roth, M.J, Georgiadis, M.M.
登録日2006-01-31
公開日2006-12-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Crystal structures of oligonucleotides including the integrase processing site of the Moloney murine leukemia virus.
Nucleic Acids Res., 34, 2006
2FVS
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A Structural Study of the CA Dinucleotide Step in the Integrase Processing Site of Moloney Murine Leukemia Virus
分子名称: 5'-D(*CP*AP*CP*AP*AP*TP*GP*AP*TP*CP*AP*TP*TP*GP*TP*G)-3', reverse transcriptase
著者Montano, S.P, Cote, M.L, Roth, M.J, Georgiadis, M.M.
登録日2006-01-31
公開日2006-12-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Crystal structures of oligonucleotides including the integrase processing site of the Moloney murine leukemia virus.
Nucleic Acids Res., 34, 2006
8CS0
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BU of 8cs0 by Molmil
Crystal structure of alien DNA CTSZZPBSBSZPPBAG in a host-guest complex with the N-terminal fragment of Moloney murine leukemia virus reverse transcriptase
分子名称: DNA (5'-D(*CP*TP*(JSP)P*(1W5)P*(1W5)P*(1WA)P*(IGU)P*(JSP))-3'), DNA (5'-D(P*(IGU)P*(JSP)P*(1W5)P*(1WA)P*(1WA)P*(IGU)P*AP*G)-3'), reverse transcriptase
著者Georgiadis, M.M.
登録日2022-05-12
公開日2023-05-17
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Alien DNA visualized at high resolution in A- and B-forms
To Be Published
8C8J
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BU of 8c8j by Molmil
Long Interspersed Nuclear Element 1 (LINE-1) reverse transcriptase ternary complex with hybrid duplex and dTTP
分子名称: 1,2-ETHANEDIOL, 1,4-DIETHYLENE DIOXIDE, CHLORIDE ION, ...
著者Nichols, C.E, Walpole, T.B, Baldwin, E.
登録日2023-01-20
公開日2023-12-20
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structures, functions and adaptations of the human LINE-1 ORF2 protein.
Nature, 626, 2024
4XO0
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Crystal structure of 5'-CTTATPPTAZZATAAG in a host-guest complex
分子名称: DNA (5'-D(*CP*TP*TP*AP*TP*(1WA)P*(1WA)P*T)-3'), DNA (5'-D(P*AP*(1W5)P*(1W5)P*AP*TP*AP*AP*G)-3'), reverse transcriptase
著者Georgiadis, M.M, Singh, I.
登録日2015-01-16
公開日2015-05-27
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural basis for a six nucleotide genetic alphabet.
J. Am. Chem. Soc., 137, 2015
4XPC
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Crystal structure of 5'- CTTATAAATTTATAAG in a host-guest complex
分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*CP*TP*TP*AP*TP*AP*AP*A)-3'), DNA (5'-D(P*TP*TP*TP*AP*TP*AP*AP*G)-3'), ...
著者Georgiadis, M.M, Singh, I.
登録日2015-01-16
公開日2015-05-27
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Structural basis for a six nucleotide genetic alphabet.
J. Am. Chem. Soc., 137, 2015
4XPE
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BU of 4xpe by Molmil
Crystal structure of 5'-CTTATGGGCCCATAAG in a host-guest complex
分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*CP*TP*TP*AP*TP*GP*GP*G)-3'), DNA (5'-D(P*CP*CP*CP*AP*TP*AP*AP*G)-3'), ...
著者Georgiadis, M.M, Singh, I.
登録日2015-01-16
公開日2015-05-27
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Structural basis for a six nucleotide genetic alphabet.
J. Am. Chem. Soc., 137, 2015
8QBM
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BU of 8qbm by Molmil
Retron-Eco1 filament with ADP-ribosylated Effector (full map with 2 segments)
分子名称: MAGNESIUM ION, Retron Ec86 putative ribosyltransferase/DNA-binding protein, Retron Ec86 reverse transcriptase, ...
著者Carabias del Rey, A, Montoya, G.
登録日2023-08-24
公開日2024-06-05
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.09 Å)
主引用文献Retron-Eco1 assembles NAD + -hydrolyzing filaments that provide immunity against bacteriophages.
Mol.Cell, 84, 2024
8QBL
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BU of 8qbl by Molmil
Retron-Eco1 filament with inactive effector (E106A, 2 segments)
分子名称: MAGNESIUM ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Retron Ec86 putative ribosyltransferase/DNA-binding protein, ...
著者Carabias del Rey, A, Montoya, G.
登録日2023-08-24
公開日2024-06-05
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.66 Å)
主引用文献Retron-Eco1 assembles NAD + -hydrolyzing filaments that provide immunity against bacteriophages.
Mol.Cell, 84, 2024
8QBK
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BU of 8qbk by Molmil
Retron-Eco1 filament with ADP-ribosylated Effector (local map with 1 segment)
分子名称: MAGNESIUM ION, Retron Ec86 putative ribosyltransferase/DNA-binding protein, Retron Ec86 reverse transcriptase, ...
著者Carabias del Rey, A, Montoya, G.
登録日2023-08-24
公開日2024-06-05
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.99 Å)
主引用文献Retron-Eco1 assembles NAD + -hydrolyzing filaments that provide immunity against bacteriophages.
Mol.Cell, 84, 2024
8BGJ
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BU of 8bgj by Molmil
Crystal structure of Reverse Transcriptase domain from Caloramator australicus CART-CAPP
分子名称: L(+)-TARTARIC ACID, MAGNESIUM ION, PENTAETHYLENE GLYCOL, ...
著者Li, A.W.H, Doherty, A.J.
登録日2022-10-27
公開日2023-06-07
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Reverse transcriptases prime DNA synthesis.
Nucleic Acids Res., 51, 2023
1ZTT
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BU of 1ztt by Molmil
Netropsin bound to d(CTTAATTCGAATTAAG) in complex with MMLV RT catalytic fragment
分子名称: 5'-D(*CP*TP*TP*AP*AP*TP*TP*C)-3', 5'-D(P*GP*AP*AP*TP*TP*AP*AP*G)-3', NETROPSIN, ...
著者Goodwin, K.D, Long, E.C, Georgiadis, M.M.
登録日2005-05-27
公開日2005-08-30
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献A host-guest approach for determining drug-DNA interactions: an example using netropsin.
Nucleic Acids Res., 33, 2005
1ZTW
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BU of 1ztw by Molmil
d(CTTAATTCGAATTAAG) complexed with Moloney Murine Leukemia Virus Reverse Transcriptase catalytic fragment
分子名称: CTTAATTC, GAATTAAG, Reverse transcriptase
著者Goodwin, K.D, Long, E.C, Georgiadis, M.M.
登録日2005-05-27
公開日2005-08-30
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A host-guest approach for determining drug-DNA interactions: an example using netropsin.
Nucleic Acids Res., 33, 2005
6MIH
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BU of 6mih by Molmil
Crystal structure of host-guest complex with PC hachimoji DNA
分子名称: DNA (5'-D(*CP*TP*TP*AP*(1WA)P*CP*(DB)P*T)-3'), DNA (5'-D(P*AP*(DS)P*GP*(1W5)P*TP*AP*AP*G)-3'), N-terminal fragment of MMLV reverse transcriptase
著者Georgiadis, M.M.
登録日2018-09-19
公開日2019-02-27
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Hachimoji DNA and RNA: A genetic system with eight building blocks.
Science, 363, 2019
6MIG
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BU of 6mig by Molmil
Crystal structure of host-guest complex with PB hachimoji DNA
分子名称: DNA (5'-D(*CP*TP*TP*AP*TP*(1WA)P*(1WA)P*(DS))-3'), DNA (5'-D(P*(DB)P*(1W5)P*(1W5)P*AP*TP*AP*AP*G)-3'), Gag-Pol polyprotein
著者Georgiadis, M.M.
登録日2018-09-19
公開日2019-02-27
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Hachimoji DNA and RNA: A genetic system with eight building blocks.
Science, 363, 2019
6MIK
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BU of 6mik by Molmil
Crystal structure of host-guest complex with PP hachimoji DNA
分子名称: DNA (5'-D(*CP*TP*TP*AP*TP*(1WA)P*(1WA)P*(DS))-3'), DNA (5'-D(P*(DB)P*(1W5)P*(1W5)P*AP*TP*AP*AP*G)-3'), N-terminal fragment of MMLV reverse transcriptase
著者Georgiadis, M.M.
登録日2018-09-19
公開日2019-02-27
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Hachimoji DNA and RNA: A genetic system with eight building blocks.
Science, 363, 2019
8GH6
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BU of 8gh6 by Molmil
Bombyx mori R2 retrotransposon initiating target-primed reverse transcription
分子名称: 28S DNA bottom strand, 3' side, 5' side (priming strand), ...
著者Wilkinson, M.E, Zhang, F.
登録日2023-03-09
公開日2023-04-05
最終更新日2023-08-16
実験手法ELECTRON MICROSCOPY (3.08 Å)
主引用文献Structure of the R2 non-LTR retrotransposon initiating target-primed reverse transcription.
Science, 380, 2023
8IBX
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BU of 8ibx by Molmil
Structure of R2 with 3'UTR and DNA in unwinding state
分子名称: 3'UTR, DNA (60-MER), Reverse transcriptase-like protein, ...
著者Deng, P, Tan, S, Wang, J, Liu, J.J.
登録日2023-02-10
公開日2023-09-20
実験手法ELECTRON MICROSCOPY (3.74 Å)
主引用文献Structural RNA components supervise the sequential DNA cleavage in R2 retrotransposon.
Cell, 186, 2023
8IBW
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Structure of R2 with 3'UTR and DNA in binding state
分子名称: 3'UTR, DNA (60-MER), Reverse transcriptase-like protein, ...
著者Deng, P, Tan, S, Wang, J, Liu, J.J.
登録日2023-02-10
公開日2023-09-20
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structural RNA components supervise the sequential DNA cleavage in R2 retrotransposon.
Cell, 186, 2023
8IBZ
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BU of 8ibz by Molmil
Structure of R2 with 5'ORF and 3'UTR
分子名称: 5ORF-linker-3UTR, Reverse transcriptase-like protein, ZINC ION
著者Deng, P, Tan, S, Wang, J, Liu, J.J.
登録日2023-02-10
公開日2023-09-20
実験手法ELECTRON MICROSCOPY (3.04 Å)
主引用文献Structural RNA components supervise the sequential DNA cleavage in R2 retrotransposon.
Cell, 186, 2023
8IBY
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Structure of R2 with 5'ORF
分子名称: 5'ORF RNA, Reverse transcriptase-like protein, ZINC ION
著者Deng, P, Tan, S, Wang, J, Liu, J.J.
登録日2023-02-10
公開日2023-09-20
実験手法ELECTRON MICROSCOPY (3.47 Å)
主引用文献Structural RNA components supervise the sequential DNA cleavage in R2 retrotransposon.
Cell, 186, 2023
2R2R
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BU of 2r2r by Molmil
d(ATTAGTTATAACTAAT) complexed with MMLV RT catalytic fragment
分子名称: DNA (5'-D(*DAP*DTP*DTP*DAP*DGP*DTP*DTP*DA)-3'), DNA (5'-D(P*DTP*DAP*DAP*DCP*DTP*DAP*DAP*DT)-3'), Reverse transcriptase
著者Goodwin, K.D, Lewis, M.A, Long, E.C, Georgiadis, M.M.
登録日2007-08-27
公開日2008-07-22
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of DNA-bound Co(III) bleomycin B2: Insights on intercalation and minor groove binding.
Proc.Natl.Acad.Sci.Usa, 105, 2008
2R2U
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BU of 2r2u by Molmil
Co(III)bleomycinB2 bithiazole/C-terminal tail domain bound to d(ATTTAGTTAACTAAAT) complexed with MMLV RT catalytic fragment
分子名称: DNA (5'-D(*DAP*DTP*DTP*DTP*DAP*DGP*DT)-3'), DNA (5'-D(P*DTP*DAP*DCP*DTP*DAP*DAP*DAP*DT)-3'), N-(4-{[amino(imino)methyl]amino}butyl)-2,4'-bi-1,3-thiazole-4-carboxamide, ...
著者Goodwin, K.D, Lewis, M.A, Long, E.C, Georgiadis, M.M.
登録日2007-08-27
公開日2008-07-22
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of DNA-bound Co(III) bleomycin B2: Insights on intercalation and minor groove binding.
Proc.Natl.Acad.Sci.Usa, 105, 2008

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