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PDB: 672 件

3G3F
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Crystal structure of the GluR6 ligand binding domain dimer with glutamate and NaCl at 1.38 Angstrom resolution
分子名称: CHLORIDE ION, GLUTAMIC ACID, Glutamate receptor, ...
著者Chaudhry, C, Mayer, M.L.
登録日2009-02-02
公開日2009-06-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.377 Å)
主引用文献Stability of ligand-binding domain dimer assembly controls kainate receptor desensitization.
Embo J., 28, 2009
3FV2
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BU of 3fv2 by Molmil
Crystal structure of the human glutamate receptor, GluR5, ligand-binding core in complex with neodysiherbaine A in space group P1
分子名称: (2R,3aR,6R,7R,7aR)-2-[(2S)-2-amino-2-carboxyethyl]-6,7-dihydroxyhexahydro-2H-furo[3,2-b]pyran-2-carboxylic acid, GLYCEROL, Glutamate receptor, ...
著者Unno, M, Sasaki, M, Ikeda-Saito, M.
登録日2009-01-15
公開日2010-01-19
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Binding and Selectivity of the Marine Toxin Neodysiherbaine A and Its Synthetic Analogues to GluK1 and GluK2 Kainate Receptors.
J.Mol.Biol., 413, 2011
3G3H
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BU of 3g3h by Molmil
Crystal structure of the GluR6 ligand binding domain dimer K665R I749L Q753K mutant with glutamate and NaCl at 1.5 Angstrom resolution
分子名称: CHLORIDE ION, GLUTAMIC ACID, Glutamate receptor, ...
著者Chaudhry, C, Mayer, M.L.
登録日2009-02-02
公開日2009-06-02
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Stability of ligand-binding domain dimer assembly controls kainate receptor desensitization.
Embo J., 28, 2009
3G3K
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BU of 3g3k by Molmil
Crystal structure of the GluR6 ligand binding domain dimer I442H K494E K665R I749L Q753K E757Q mutant with glutamate and NaCl at 1.24 Angstrom resolution
分子名称: CHLORIDE ION, GLUTAMIC ACID, Glutamate receptor, ...
著者Chaudhry, C, Mayer, M.L.
登録日2009-02-02
公開日2009-06-02
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (1.24 Å)
主引用文献Stability of ligand-binding domain dimer assembly controls kainate receptor desensitization.
Embo J., 28, 2009
4BDO
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BU of 4bdo by Molmil
Crystal structure of the GluK2 K531A-T779G LBD dimer in complex with kainate
分子名称: 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, GLUTAMATE RECEPTOR, IONOTROPIC KAINATE 2, ...
著者Nayeem, N, Mayans, O, Green, T.
登録日2012-10-05
公開日2013-04-10
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Correlating Efficacy and Desensitization with Gluk2 Ligand-Binding Domain Movements.
Open Biol., 3, 2013
4BDR
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BU of 4bdr by Molmil
Crystal structure of the GluK2 R775A LBD dimer in complex with kainate
分子名称: 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, CHLORIDE ION, GLUTAMATE RECEPTOR, ...
著者Nayeem, N, Mayans, O, Green, T.
登録日2012-10-05
公開日2013-04-10
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Correlating Efficacy and Desensitization with Gluk2 Ligand-Binding Domain Movements.
Open Biol., 3, 2013
4BDM
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BU of 4bdm by Molmil
Crystal structure of the GluK2 K531A LBD dimer in complex with kainate
分子名称: 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, GLUTAMATE RECEPTOR, IONOTROPIC KAINATE 2
著者Nayeem, N, Mayans, O, Green, T.
登録日2012-10-05
公開日2013-04-10
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Correlating Efficacy and Desensitization with Gluk2 Ligand-Binding Domain Movements.
Open Biol., 3, 2013
6YK3
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BU of 6yk3 by Molmil
Structure of the AMPA receptor GluA2o ligand-binding domain (S1S2J) in complex with the compound ( S) - 1- [2'-Amino-2'-carboxyethyl]-5 ,7- dihydropyrrolo[3,4-d]pyrimidin-2,4(1H,3H)-dione at resolution 1.20A
分子名称: (S)-1-[2'-Amino-2'-carboxyethyl]-5,7-dihydropyrrolo[3,4-d]pyrimidin-2,4(1H,3H)-dione, AMMONIUM ION, CHLORIDE ION, ...
著者Frydenvang, K, Kastrup, J.S.
登録日2020-04-05
公開日2020-06-03
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Ionotropic Glutamate Receptor GluA2 in Complex with Bicyclic Pyrimidinedione-Based Compounds: When Small Compound Modifications Have Distinct Effects on Binding Interactions.
Acs Chem Neurosci, 11, 2020
4Q30
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BU of 4q30 by Molmil
Nitrowillardiine bound to the ligand binding domain of GluA2 at pH 3.5
分子名称: 3-(5-nitro-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-L-alanine, Glutamate receptor 2 CHIMERIC PROTEIN, ZINC ION
著者Ahmed, A.H, Oswald, R.E.
登録日2014-04-10
公開日2014-06-04
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Thermodynamics and mechanism of the interaction of willardiine partial agonists with a glutamate receptor: implications for drug development.
Biochemistry, 53, 2014
4BDL
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BU of 4bdl by Molmil
Crystal structure of the GluK2 K531A LBD dimer in complex with glutamate
分子名称: GLUTAMATE RECEPTOR, IONOTROPIC KAINATE 2, GLUTAMIC ACID, ...
著者Nayeem, N, Mayans, O, Green, T.
登録日2012-10-05
公開日2013-04-10
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Correlating Efficacy and Desensitization with Gluk2 Ligand-Binding Domain Movements.
Open Biol., 3, 2013
6XSR
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BU of 6xsr by Molmil
Crystal structure of GluA2 AMPA receptor in complex with trans-4-butylcyclohexane carboxylic acid (4-BCCA) inhibitor
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 2, trans-4-butylcyclohexane-1-carboxylic acid
著者Yelshanskaya, M.V, Singh, A.K, Sobolevsky, A.I.
登録日2020-07-16
公開日2020-12-30
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (4.25 Å)
主引用文献Structural basis of AMPA receptor inhibition by trans-4-butylcyclohexane carboxylic acid.
Br.J.Pharmacol., 179, 2022
4PE5
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BU of 4pe5 by Molmil
Crystal Structure of GluN1a/GluN2B NMDA Receptor Ion Channel
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-[(1R,2S)-2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl]phenol, ...
著者Karakas, E, Furukawa, H.
登録日2014-04-22
公開日2014-06-04
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.96 Å)
主引用文献Crystal structure of a heterotetrameric NMDA receptor ion channel.
Science, 344, 2014
4O3B
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BU of 4o3b by Molmil
Crystal structure of an open/closed glua2 ligand-binding domain dimer at 1.91 A resolution
分子名称: ACETATE ION, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
著者Krintel, C, de Rabassa, A.C, Frydenvang, K, Gajhede, M, Kastrup, J.S.
登録日2013-12-18
公開日2014-04-16
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.906 Å)
主引用文献L-Asp is a useful tool in the purification of the ionotropic glutamate receptor A2 ligand-binding domain.
Febs J., 281, 2014
4O3A
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BU of 4o3a by Molmil
Crystal structure of the glua2 ligand-binding domain in complex with L-aspartate at 1.80 a resolution
分子名称: ACETATE ION, ASPARTIC ACID, CHLORIDE ION, ...
著者Krintel, C, Frydenvang, F, Gajhede, M, Kastrup, J.S.
登録日2013-12-18
公開日2014-04-16
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献L-Asp is a useful tool in the purification of the ionotropic glutamate receptor A2 ligand-binding domain.
Febs J., 281, 2014
4O3C
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BU of 4o3c by Molmil
Crystal structure of the GLUA2 ligand-binding domain in complex with L-aspartate at 1.50 A resolution
分子名称: ACETATE ION, ASPARTIC ACID, CHLORIDE ION, ...
著者Krintel, C, Frydenvang, K, Kaern, A.M, Gajhede, M, Kastrup, J.S.
登録日2013-12-18
公開日2014-04-16
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献L-Asp is a useful tool in the purification of the ionotropic glutamate receptor A2 ligand-binding domain.
Febs J., 281, 2014
6WHU
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BU of 6whu by Molmil
GluN1b-GluN2B NMDA receptor in complex with SDZ 220-040 and L689,560, class 1
分子名称: (2R,4S)-5,7-dichloro-4-[(phenylcarbamoyl)amino]-1,2,3,4-tetrahydroquinoline-2-carboxylic acid, (2S)-2-amino-3-[2',4'-dichloro-4-hydroxy-5-(phosphonomethyl)biphenyl-3-yl]propanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Chou, T, Tajima, N, Furukawa, H.
登録日2020-04-08
公開日2020-08-05
実験手法ELECTRON MICROSCOPY (3.93 Å)
主引用文献Structural Basis of Functional Transitions in Mammalian NMDA Receptors.
Cell, 182, 2020
6WHW
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BU of 6whw by Molmil
GluN1b-GluN2B NMDA receptor in complex with GluN2B antagonist SDZ 220-040, class 1
分子名称: (2S)-2-amino-3-[2',4'-dichloro-4-hydroxy-5-(phosphonomethyl)biphenyl-3-yl]propanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, Ionotropic glutamate receptor , ...
著者Chou, T, Tajima, N, Furukawa, H.
登録日2020-04-08
公開日2020-07-15
最終更新日2020-08-05
実験手法ELECTRON MICROSCOPY (4.09 Å)
主引用文献Structural Basis of Functional Transitions in Mammalian NMDA Receptors.
Cell, 182, 2020
6YK4
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BU of 6yk4 by Molmil
Structure of the AMPA receptor GluA2o ligand-binding domain (S1S2J) in complex with the compound ( S) - 1- [2'-Amino-2'-carboxyethyl]-6-methyl-5 ,7- dihydropyrrolo[3,4-d]pyrimidin-2,4(1H,3H)-dione at resolution 1.00A
分子名称: (2~{S})-2-azanyl-3-[6-methyl-2,4-bis(oxidanylidene)-5,7-dihydropyrrolo[3,4-d]pyrimidin-1-yl]propanoic acid, CHLORIDE ION, GLYCEROL, ...
著者Frydenvang, K, Kastrup, J.S.
登録日2020-04-05
公開日2020-06-03
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (0.999 Å)
主引用文献Ionotropic Glutamate Receptor GluA2 in Complex with Bicyclic Pyrimidinedione-Based Compounds: When Small Compound Modifications Have Distinct Effects on Binding Interactions.
Acs Chem Neurosci, 11, 2020
4QF9
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BU of 4qf9 by Molmil
Structure of GluK1 ligand-binding domain (S1S2) in complex with (S)-2-amino-4-(2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-6-yl)butanoic acid at 2.28 A resolution
分子名称: (2S)-2-amino-4-(2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-6-yl)butanoic acid, ACETATE ION, CHLORIDE ION, ...
著者Kristensen, C.M, Frydenvang, K, Kastrup, J.S.
登録日2014-05-20
公開日2015-04-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Binding Mode of an alpha-Amino Acid-Linked Quinoxaline-2,3-dione Analogue at Glutamate Receptor Subtype GluK1.
ACS Chem Neurosci, 6, 2015
4NWD
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BU of 4nwd by Molmil
Crystal structure of the kainate receptor GluK3 ligand-binding domain in complex with the agonist (2S,4R)-4-(3-Methylamino-3-oxopropyl)glutamic acid at 2.6 A resolution
分子名称: (4R)-4-[3-(methylamino)-3-oxopropyl]-L-glutamic acid, CHLORIDE ION, Glutamate receptor ionotropic, ...
著者Venskutonyte, R, Larsen, A.P, Frydenvang, K, Gajhede, M, Kastrup, J.S.
登録日2013-12-06
公開日2014-08-06
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Molecular Recognition of Two 2,4-syn-Functionalized (S)-Glutamate Analogues by the Kainate Receptor GluK3 Ligand Binding Domain.
Chemmedchem, 9, 2014
6YK2
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BU of 6yk2 by Molmil
Structure of the AMPA receptor GluA2o ligand-binding domain (S1S2J) in complex with the compound (S)-1-[2'-Amino-2'-carboxyethyl]-5,7-dihydrothieno[3,4-d]pyrimidin- 2,4(1H,3H)-dione at resolution 1.60A
分子名称: (2~{S})-2-azanyl-3-[2,4-bis(oxidanylidene)-5,7-dihydrothieno[3,4-d]pyrimidin-1-yl]propanoic acid, CHLORIDE ION, GLYCEROL, ...
著者Frydenvang, K, Kastrup, J.S.
登録日2020-04-05
公開日2020-06-03
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.612 Å)
主引用文献Ionotropic Glutamate Receptor GluA2 in Complex with Bicyclic Pyrimidinedione-Based Compounds: When Small Compound Modifications Have Distinct Effects on Binding Interactions.
Acs Chem Neurosci, 11, 2020
6YK5
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BU of 6yk5 by Molmil
Structure of the AMPA receptor GluA2o ligand-binding domain (S1S2J) in complex with the compound (S)-1-(2'-Amino-2'-carboxyethyl)-5,7-dihydrofuro[3,4-d]- pyrimidine-2,4(1H,3H)-dione at resolution 1.15A
分子名称: (S)-1-(2'-Amino-2'-carboxyethyl)-5,7-dihydrofuro[3,4-d]-pyrimidine-2,4(1H,3H)-dione, CHLORIDE ION, GLYCEROL, ...
著者Frydenvang, K, Kastrup, J.S.
登録日2020-04-05
公開日2020-06-03
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Ionotropic Glutamate Receptor GluA2 in Complex with Bicyclic Pyrimidinedione-Based Compounds: When Small Compound Modifications Have Distinct Effects on Binding Interactions.
Acs Chem Neurosci, 11, 2020
4NWC
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BU of 4nwc by Molmil
Crystal structure of the GluK3 ligand-binding domain (S1S2) in complex with the agonist (2S,4R)-4-(3-Methoxy-3-oxopropyl)glutamic acid at 2.01 A resolution.
分子名称: (2S,4R)-4-(3-Methoxy-3-oxopropyl) glutamic acid, CHLORIDE ION, Glutamate receptor ionotropic, ...
著者Larsen, A.P, Venskutonyte, R, Frydenvang, K, Gajhede, M, Kastrup, J.S.
登録日2013-12-06
公開日2014-08-06
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.012 Å)
主引用文献Molecular Recognition of Two 2,4-syn-Functionalized (S)-Glutamate Analogues by the Kainate Receptor GluK3 Ligand Binding Domain.
Chemmedchem, 9, 2014
6YK6
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BU of 6yk6 by Molmil
Structure of the AMPA receptor GluA2o ligand-binding domain (S1S2J) in complex with the compound (S)-1-(2'-Amino-2'-carboxyethyl)furo[3,4-d]pyrimidin-2,4-dione at resolution 1.47A
分子名称: (S)-1-(2'-Amino-2'-carboxyethyl)furo[3,4-d]pyrimidin-2,4-dione, CHLORIDE ION, GLYCEROL, ...
著者Frydenvang, K, Kastrup, J.S.
登録日2020-04-05
公開日2020-06-03
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.469 Å)
主引用文献Ionotropic Glutamate Receptor GluA2 in Complex with Bicyclic Pyrimidinedione-Based Compounds: When Small Compound Modifications Have Distinct Effects on Binding Interactions.
Acs Chem Neurosci, 11, 2020
4DLD
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BU of 4dld by Molmil
Crystal structure of the GluK1 ligand-binding domain (S1S2) in complex with the antagonist (S)-2-amino-3-(2-(2-carboxyethyl)-5-chloro-4-nitrophenyl)propionic acid at 2.0 A resolution
分子名称: (S)-2-amino-3-(2-(2-carboxyethyl)-5-chloro-4-nitrophenyl)propionic acid, CHLORIDE ION, GLYCEROL, ...
著者Venskutonyte, R, Frydenvang, K, Kastrup, J.S.
登録日2012-02-06
公開日2012-10-10
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural and pharmacological characterization of phenylalanine-based AMPA receptor antagonists at kainate receptors
Chemmedchem, 7, 2012

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