7YFF

Structure of GluN1a-GluN2D NMDA receptor in complex with agonist glycine and competitive antagonist CPP.

Summary for 7YFF

Entry DOI	10.2210/pdb7yff/pdb
EMDB information	33788
Descriptor	Glutamate receptor ionotropic, NMDA 1, Glutamate receptor ionotropic, NMDA 2D, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
Functional Keywords	ion channel, cryo-em structure, glutamate receptor, synaptic protein, electron transport
Biological source	Homo sapiens (human) More
Total number of polymer chains	4
Total formula weight	386627.11
Authors	Zhang, J.L.,Zhu, S.J.,Zhang, M. (deposition date: 2022-07-08, release date: 2023-04-12, Last modification date: 2023-08-02)
Primary citation	Zhang, J.,Zhang, M.,Wang, Q.,Wen, H.,Liu, Z.,Wang, F.,Wang, Y.,Yao, F.,Song, N.,Kou, Z.,Li, Y.,Guo, F.,Zhu, S. Distinct structure and gating mechanism in diverse NMDA receptors with GluN2C and GluN2D subunits. Nat.Struct.Mol.Biol., 30:629-639, 2023 Cited by PubMed: 36959261 DOI: 10.1038/s41594-023-00959-z PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.6 Å)

Structure validation