8R36
Crystal structure of the Gluk1 ligand-binding domain in complex with kainate and BPAM538 at 1.90 A resolution
Summary for 8R36
Entry DOI | 10.2210/pdb8r36/pdb |
Descriptor | Glutamate receptor ionotropic, kainate 1, 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, SULFATE ION, ... (7 entities in total) |
Functional Keywords | ionotropic glutamate receptor, gluk1 ligand-binding domain, membrane protein, positive allosteric modulator, kainate |
Biological source | Rattus norvegicus (Norway rat) More |
Total number of polymer chains | 2 |
Total formula weight | 60026.02 |
Authors | Bay, Y.,Frantsen, S.M.,Frydenvang, K.,Kastrup, J.S. (deposition date: 2023-11-08, release date: 2024-08-14, Last modification date: 2024-10-23) |
Primary citation | Bay, Y.,Cabello, F.J.M.,Koens, C.C.,Frantsen, S.M.,Pickering, D.S.,Frydenvang, K.,Francotte, P.,Pirotte, B.,Kristensen, A.S.,Bowie, D.,Kastrup, J.S. Crystal structure of the GluK1 ligand-binding domain with kainate and the full-spanning positive allosteric modulator BPAM538. J.Struct.Biol., 216:108113-108113, 2024 Cited by PubMed: 39079583DOI: 10.1016/j.jsb.2024.108113 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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