4DR2
| Crystal structure of the Thermus thermophilus (HB8) 30S ribosomal subunit with multiple copies of paromomycin molecules bound | 分子名称: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | 著者 | Demirci, H, Murphy IV, F, Murphy, E, Gregory, S.T, Dahlberg, A.E, Jogl, G. | 登録日 | 2012-02-16 | 公開日 | 2012-11-14 | 最終更新日 | 2013-01-30 | 実験手法 | X-RAY DIFFRACTION (3.249 Å) | 主引用文献 | A structural basis for streptomycin-induced misreading of the genetic code. Nat Commun, 4, 2013
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1XMO
| Crystal Structure of mnm5U34t6A37-tRNALysUUU Complexed with AAG-mRNA in the Decoding Center | 分子名称: | 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | 著者 | Murphy, F.V, Ramakrishnan, V, Malkiewicz, A, Agris, P.F. | 登録日 | 2004-10-04 | 公開日 | 2004-12-14 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | 主引用文献 | The role of modifications in codon discrimination by tRNA(Lys)(UUU). Nat.Struct.Mol.Biol., 11, 2004
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6OXA
| Dimeric E.coli YoeB bound to Thermus thermophilus 70S pre-cleavage (AAU) | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Pavelich, I.J, Hoffer, E.D, Maehigashi, T, Dunham, C.M. | 登録日 | 2019-05-13 | 公開日 | 2019-08-21 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | 主引用文献 | Monomeric YoeB toxin retains RNase activity but adopts an obligate dimeric form for thermal stability. Nucleic Acids Res., 47, 2019
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7LH5
| Crystal structure of the Thermus thermophilus 70S ribosome in complex with plazomicin, mRNA and tRNAs | 分子名称: | (2S)-4-amino-N-[(1R,2S,3S,4R,5S)-5-amino-4-{[(2S,3R)-3-amino-6-{[(2-hydroxyethyl)amino]methyl}-3,4-dihydro-2H-pyran-2-y l]oxy}-2-{[3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl]oxy}-3-hydroxycyclohexyl]-2-hydroxybutanamide, 16S ribosomal RNA, 23S ribosomal RNA, ... | 著者 | Golkar, T, Berghuis, A.M, Schmeing, T.M. | 登録日 | 2021-01-21 | 公開日 | 2021-06-02 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.27 Å) | 主引用文献 | Structural basis for plazomicin antibiotic action and resistance. Commun Biol, 4, 2021
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6GZQ
| T. thermophilus hibernating 70S ribosome | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Flygaard, R.K, Jenner, L.B. | 登録日 | 2018-07-04 | 公開日 | 2018-10-24 | 実験手法 | ELECTRON MICROSCOPY (3.28 Å) | 主引用文献 | Cryo-EM structure of the hibernating Thermus thermophilus 100S ribosome reveals a protein-mediated dimerization mechanism. Nat Commun, 9, 2018
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4LF9
| Crystal Structure of 30S ribosomal subunit from Thermus thermophilus | 分子名称: | (2R,3R,4R,5R)-2-((1S,2S,3R,4S,6R)-4,6-DIAMINO-3-((2R,3R,6S)-3-AMINO-6-(AMINOMETHYL)-TETRAHYDRO-2H-PYRAN-2-YLOXY)-2-HYDROXYCYCLOHEXYLOXY)-5-METHYL-4-(METHYLAMINO)-TETRAHYDRO-2H-PYRAN-3,5-DIOL, 16S rRNA, MAGNESIUM ION, ... | 著者 | Demirci, H, Belardinelli, R, Carr, J, Murphy IV, F, Jogl, G, Dahlberg, A.E, Gregory, S.T. | 登録日 | 2013-06-26 | 公開日 | 2014-07-02 | 実験手法 | X-RAY DIFFRACTION (3.2811 Å) | 主引用文献 | Crystal Structure of 30S ribosomal subunit from Thermus thermophilus to be published, 2013
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4DV7
| Crystal structure of the Thermus thermophilus 30S ribosomal subunit with a 16S rRNA mutation, A915G, bound with streptomycin | 分子名称: | 16S rRNA, MAGNESIUM ION, STREPTOMYCIN, ... | 著者 | Demirci, H, Murphy IV, F, Murphy, E, Gregory, S.T, Dahlberg, A.E, Jogl, G. | 登録日 | 2012-02-22 | 公開日 | 2013-02-27 | 実験手法 | X-RAY DIFFRACTION (3.294 Å) | 主引用文献 | A structural basis for streptomycin resistance To be Published
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4DV6
| Crystal structure of the Thermus thermophilus 30S ribosomal subunit with a 16S rRNA mutation, A915G | 分子名称: | 16S rRNA, MAGNESIUM ION, ZINC ION, ... | 著者 | Demirci, H, Murphy IV, F, Murphy, E, Gregory, S.T, Dahlberg, A.E, Jogl, G. | 登録日 | 2012-02-22 | 公開日 | 2013-02-27 | 実験手法 | X-RAY DIFFRACTION (3.297 Å) | 主引用文献 | A structural basis for streptomycin resistance To be Published
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4GKJ
| Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a human mitochondrial anticodon stem loop (ASL) of transfer RNA Methionine (TRNAMET) bound to an mRNA with an AUG-codon in the A-site and paromomycin. | 分子名称: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | 著者 | Cantara, W.A, Murphy IV, F.V, Spears, J.L, Demirci, H, Agris, P.F. | 登録日 | 2012-08-11 | 公開日 | 2013-06-05 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.298 Å) | 主引用文献 | Expanded use of sense codons is regulated by modified cytidines in tRNA. Proc.Natl.Acad.Sci.USA, 110, 2013
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4V9A
| Crystal Structure of the 70S ribosome with tetracycline. | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, ... | 著者 | Jenner, L, Yusupov, M, Yusupova, G. | 登録日 | 2012-07-18 | 公開日 | 2014-07-09 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.2999 Å) | 主引用文献 | Structural basis for potent inhibitory activity of the antibiotic tigecycline during protein synthesis. Proc.Natl.Acad.Sci.USA, 110, 2013
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5CZP
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4WSM
| Complex of 70S ribosome with tRNA-Leu and mRNA with G-U mismatch in the first position in the A- and P-sites | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G. | 登録日 | 2014-10-28 | 公開日 | 2015-06-10 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Structural insights into the translational infidelity mechanism. Nat Commun, 6, 2015
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4W4G
| Postcleavage state of 70S bound to HigB toxin and AAA (lysine) codon | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Schureck, M.A, Maehigashi, T, Dunkle, J.A, Dunham, C.M. | 登録日 | 2014-08-14 | 公開日 | 2015-10-21 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Defining the mRNA recognition signature of a bacterial toxin protein. Proc.Natl.Acad.Sci.USA, 112, 2015
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4V5C
| Structure of the Thermus thermophilus 70S ribosome in complex with mRNA, paromomycin, acylated A-site tRNA, deacylated P-site tRNA, and E-site tRNA. | 分子名称: | 16S ribosomal RNA, 23S Ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, ... | 著者 | Voorhees, R.M, Weixlbaumer, A, Loakes, D, Kelley, A.C, Ramakrishnan, V. | 登録日 | 2009-03-24 | 公開日 | 2014-07-09 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Insights Into Substrate Stabilization from Snapshots of the Peptidyl Transferase Center of the Intact 70S Ribosome Nat.Struct.Mol.Biol., 16, 2009
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4V7J
| Structure of RelE nuclease bound to the 70S ribosome (precleavage state) | 分子名称: | 30S ribosomal protein S10, 30S ribosomal protein S11, 30S ribosomal protein S12, ... | 著者 | Neubauer, C, Gao, Y.-G, Andersen, K.R, Dunham, C.M, Kelley, A.C, Hentschel, J, Gerdes, K, Ramakrishnan, V, Brodersen, D.E. | 登録日 | 2009-11-02 | 公開日 | 2014-07-09 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | The structural basis for mRNA recognition and cleavage by the ribosome-dependent endonuclease RelE. Cell(Cambridge,Mass.), 139, 2009
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4DR6
| Crystal structure of the Thermus thermophilus (HB8) 30S ribosomal subunit with codon, near-cognate transfer RNA anticodon stem-loop mismatched at the first codon position and streptomycin bound | 分子名称: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | 著者 | Demirci, H, Murphy IV, F, Murphy, E, Gregory, S.T, Dahlberg, A.E, Jogl, G. | 登録日 | 2012-02-16 | 公開日 | 2012-11-14 | 最終更新日 | 2013-01-30 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | A structural basis for streptomycin-induced misreading of the genetic code. Nat Commun, 4, 2013
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4WZO
| Complex of 70S ribosome with tRNA-fMet and mRNA | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G. | 登録日 | 2014-11-20 | 公開日 | 2015-06-10 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Structural insights into the translational infidelity mechanism. Nat Commun, 6, 2015
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5WNT
| Crystal Structure of 30S ribosomal subunit from Thermus thermophilus | 分子名称: | (1R,2S,3S,4R,6R)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-alpha-L-altropyranosyl)-beta-L-arabinofuranosyl]oxy}-3-hydroxycyclohexyl 2-amino-2-deoxy-alpha-D-allopyranoside, 16S Ribosomal RNA rRNA, MAGNESIUM ION, ... | 著者 | DeMirci, H. | 登録日 | 2017-08-01 | 公開日 | 2018-02-21 | 最終更新日 | 2020-10-21 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | 2'-O-methylation in mRNA disrupts tRNA decoding during translation elongation. Nat. Struct. Mol. Biol., 25, 2018
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5WNV
| Crystal Structure of 30S ribosomal subunit from Thermus thermophilus | 分子名称: | (1R,2S,3S,4R,6R)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-alpha-L-altropyranosyl)-beta-L-arabinofuranosyl]oxy}-3-hydroxycyclohexyl 2-amino-2-deoxy-alpha-D-allopyranoside, 16S Ribosomal RNA rRNA, 30S ribosomal protein S10, ... | 著者 | DeMirci, H. | 登録日 | 2017-08-01 | 公開日 | 2018-02-21 | 最終更新日 | 2020-10-21 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | 2'-O-methylation in mRNA disrupts tRNA decoding during translation elongation. Nat. Struct. Mol. Biol., 25, 2018
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5WNP
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4V8E
| Crystal structure analysis of ribosomal decoding (near-cognate tRNA-tyr complex). | 分子名称: | 16S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... | 著者 | Jenner, L, Demeshkina, N, Yusupov, M, Yusupova, G. | 登録日 | 2011-12-07 | 公開日 | 2014-07-09 | 最終更新日 | 2019-07-03 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | A new understanding of the decoding principle on the ribosome. Nature, 484, 2012
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4V8F
| Crystal structure analysis of ribosomal decoding (near-cognate tRNA-ttyr complex with paromomycin). | 分子名称: | 16S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... | 著者 | Jenner, L, Demeshkina, N, Yusupov, M, Yusupova, G. | 登録日 | 2011-12-07 | 公開日 | 2014-07-09 | 最終更新日 | 2019-07-03 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | A new understanding of the decoding principle on the ribosome. Nature, 484, 2012
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4V9I
| Crystal structure of thermus thermophilus 70S in complex with tRNAs and mRNA containing a pseudouridine in a stop codon | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S Ribosomal protein S10, ... | 著者 | Fernandez, I.S, Ng, C.L, Kelley, A.C, Guowei, W, Yu, Y.T, Ramakrishnan, V. | 登録日 | 2013-04-04 | 公開日 | 2014-07-09 | 最終更新日 | 2014-12-10 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Unusual base pairing during the decoding of a stop codon by the ribosome. Nature, 500, 2013
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7V2L
| T.thermophilus 30S ribosome with KsgA, class K1k2 | 分子名称: | 16s ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | 著者 | Raina, R, Singh, J, Anand, R, Vinothkumar, K.R. | 登録日 | 2021-08-09 | 公開日 | 2022-04-06 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Decoding the Mechanism of Specific RNA Targeting by Ribosomal Methyltransferases. Acs Chem.Biol., 17, 2022
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7V2P
| T.thermophilus 30S ribosome with KsgA, class K5 | 分子名称: | 16s ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | 著者 | Raina, R, Singh, J, Anand, R, Vinothkumar, K.R. | 登録日 | 2021-08-09 | 公開日 | 2022-04-06 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Decoding the Mechanism of Specific RNA Targeting by Ribosomal Methyltransferases. Acs Chem.Biol., 17, 2022
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