4GKJ

Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a human mitochondrial anticodon stem loop (ASL) of transfer RNA Methionine (TRNAMET) bound to an mRNA with an AUG-codon in the A-site and paromomycin.

Summary for 4GKJ

Entry DOI	10.2210/pdb4gkj/pdb
Related	2KRY 2UUC 3T1Y
Descriptor	16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... (26 entities in total)
Functional Keywords	translation initiation, 5-formylcytidine, ribosome-antibiotic complex, ribosome/antibiotic
Biological source	Thermus thermophilus More
Total number of polymer chains	23
Total formula weight	777325.73
Authors	Cantara, W.A.,Murphy IV, F.V.,Spears, J.L.,Demirci, H.,Agris, P.F. (deposition date: 2012-08-11, release date: 2013-06-05, Last modification date: 2024-02-28)
Primary citation	Cantara, W.A.,Murphy, F.V.,Demirci, H.,Agris, P.F. Expanded use of sense codons is regulated by modified cytidines in tRNA. Proc.Natl.Acad.Sci.USA, 110:10964-10969, 2013 Cited by PubMed: 23781103 DOI: 10.1073/pnas.1222641110 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.298 Å)

Structure validation