7LH5

Crystal structure of the Thermus thermophilus 70S ribosome in complex with plazomicin, mRNA and tRNAs

This is a non-PDB format compatible entry.

Summary for 7LH5

• Entry DOI: 10.2210/pdb7lh5/pdb
• Descriptor: 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... (62 entities in total)
• Functional Keywords: 70s ribosome, plazomicin, antibiotic resistance, aminoglycoside, ribosome
• Biological source: Escherichia coli; More
• Total number of polymer chains: 118
• Total formula weight: 4589368.96

Authors

Golkar, T.,Berghuis, A.M.,Schmeing, T.M. (deposition date: 2021-01-21, release date: 2021-06-02, Last modification date: 2023-10-18)

• Primary citation: Golkar, T.,Bassenden, A.V.,Maiti, K.,Arya, D.P.,Schmeing, T.M.,Berghuis, A.M.; Structural basis for plazomicin antibiotic action and resistance.; Commun Biol, 4:729-729, 2021; PubMed: 34117352; DOI: 10.1038/s42003-021-02261-4

Experimental method

X-RAY DIFFRACTION (3.27 Å)