8FTQ
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![BU of 8ftq by Molmil](/molmil-images/mine/8ftq) | Crystal structure of hRpn13 Pru domain in complex with Ubiquitin and XL44 | 分子名称: | N-(3-{[(3R)-5-fluoro-2-oxo-2,3-dihydro-1H-indol-3-yl]methyl}phenyl)-4-methoxybenzamide, Proteasomal ubiquitin receptor ADRM1, Ubiquitin | 著者 | Walters, K.J, Lu, X, Chandravanshi, M. | 登録日 | 2023-01-13 | 公開日 | 2024-03-27 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | A structure-based designed small molecule depletes hRpn13 Pru and a select group of KEN box proteins. Nat Commun, 15, 2024
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6W9S
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![BU of 6w9s by Molmil](/molmil-images/mine/6w9s) | |
3V6E
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![BU of 3v6e by Molmil](/molmil-images/mine/3v6e) | Crystal Structure of USP2 and a mutant form of Ubiquitin | 分子名称: | CHLORIDE ION, GLYCEROL, Ubiquitin, ... | 著者 | Neculai, M, Ernst, A, Sidhu, S, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | 登録日 | 2011-12-19 | 公開日 | 2012-12-19 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | A strategy for modulation of enzymes in the ubiquitin system. Science, 339, 2013
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6AQR
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![BU of 6aqr by Molmil](/molmil-images/mine/6aqr) | SAGA DUB module Ubp8(C146A)/Sgf11/Sus1/Sgf73 bound to monoubiquitin | 分子名称: | Polyubiquitin-C, SAGA-associated factor 11, SAGA-associated factor 73, ... | 著者 | Morrow, M.E, Morgan, M.T, Wolberger, C. | 登録日 | 2017-08-21 | 公開日 | 2018-07-04 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Active site alanine mutations convert deubiquitinases into high-affinity ubiquitin-binding proteins. EMBO Rep., 19, 2018
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6TUV
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![BU of 6tuv by Molmil](/molmil-images/mine/6tuv) | |
3Q3F
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![BU of 3q3f by Molmil](/molmil-images/mine/3q3f) | Engineering Domain-Swapped Binding Interfaces by Mutually Exclusive Folding: Insertion of Ubiquitin into position 103 of Barnase | 分子名称: | Ribonuclease/Ubiquitin chimeric protein, SULFATE ION | 著者 | Ha, J.-H, Karchin, J.M, Walker-Kopp, N, Huang, L.-S, Berry, E.A, Loh, S.N. | 登録日 | 2010-12-21 | 公開日 | 2012-01-25 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.169 Å) | 主引用文献 | Engineering domain-swapped binding interfaces by mutually exclusive folding. J.Mol.Biol., 416, 2012
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4AUQ
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![BU of 4auq by Molmil](/molmil-images/mine/4auq) | Structure of BIRC7-UbcH5b-Ub complex. | 分子名称: | BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 7, POLYUBIQUITIN-C, UBIQUITIN-CONJUGATING ENZYME E2 D2, ... | 著者 | Dou, H, Buetow, L, Sibbet, G.J, Cameron, K, Huang, D.T. | 登録日 | 2012-05-21 | 公開日 | 2012-08-15 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.176 Å) | 主引用文献 | Birc7-E2 Ubiquitin Conjugate Structure Reveals the Mechanism of Ubiquitin Transfer by a Ring Dimer. Nat.Struct.Mol.Biol., 19, 2012
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1SIF
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![BU of 1sif by Molmil](/molmil-images/mine/1sif) | Crystal structure of a multiple hydrophobic core mutant of ubiquitin | 分子名称: | ubiquitin | 著者 | Benitez-Cardoza, C.G, Stott, K, Hirshberg, M, Went, H.M, Woolfson, D.N, Jackson, S.E. | 登録日 | 2004-02-29 | 公開日 | 2004-07-27 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | 主引用文献 | Exploring sequence/folding space: folding studies on multiple hydrophobic core mutants of ubiquitin Biochemistry, 43, 2004
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6TXB
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![BU of 6txb by Molmil](/molmil-images/mine/6txb) | |
6SQR
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![BU of 6sqr by Molmil](/molmil-images/mine/6sqr) | Crystal structure of Cat MDM2-S429E RING domain bound to UbcH5B-Ub | 分子名称: | 1,2-ETHANEDIOL, E3 ubiquitin-protein ligase Mdm2, NITRATE ION, ... | 著者 | Magnussen, H.M, Ahmed, S.F, Huang, D.T. | 登録日 | 2019-09-04 | 公開日 | 2020-05-06 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | 主引用文献 | Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain. Nat Commun, 11, 2020
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5ZQ3
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![BU of 5zq3 by Molmil](/molmil-images/mine/5zq3) | PDE-Ubiquitin | 分子名称: | SidE, Ubiquitin | 著者 | Wang, Y, Gao, A, Gao, P. | 登録日 | 2018-04-17 | 公開日 | 2018-05-23 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.182 Å) | 主引用文献 | Structural Insights into Non-canonical Ubiquitination Catalyzed by SidE. Cell, 173, 2018
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3NOB
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![BU of 3nob by Molmil](/molmil-images/mine/3nob) | |
6NXK
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![BU of 6nxk by Molmil](/molmil-images/mine/6nxk) | Ubiquitin binding variants | 分子名称: | Anaphase-promoting complex subunit 2, Polyubiquitin-C | 著者 | Miller, D.J, Watson, E.R. | 登録日 | 2019-02-08 | 公開日 | 2020-01-15 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Protein engineering of a ubiquitin-variant inhibitor of APC/C identifies a cryptic K48 ubiquitin chain binding site. Proc.Natl.Acad.Sci.USA, 116, 2019
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4XOK
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![BU of 4xok by Molmil](/molmil-images/mine/4xok) | Observing the overall rocking motion of a protein in a crystal. | 分子名称: | Ubiquitin, ZINC ION | 著者 | Coquelle, N, Ma, P, Schanda, P, Colletier, J.P. | 登録日 | 2015-01-16 | 公開日 | 2015-10-14 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Observing the overall rocking motion of a protein in a crystal. Nat Commun, 6, 2015
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3A33
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![BU of 3a33 by Molmil](/molmil-images/mine/3a33) | UbcH5b~Ubiquitin Conjugate | 分子名称: | GLYCEROL, Ubiquitin, Ubiquitin-conjugating enzyme E2 D2 | 著者 | Sakata, E, Satoh, T, Yamamoto, S, Yamaguchi, Y, Yagi-Utsumi, M, Kurimoto, E, Wakatsuki, S, Kato, K. | 登録日 | 2009-06-08 | 公開日 | 2009-11-24 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal Structure of UbcH5b~Ubiquitin Intermediate: Insight into the Formation of the Self-Assembled E2~Ub Conjugates Structure, 18, 2010
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6UPU
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![BU of 6upu by Molmil](/molmil-images/mine/6upu) | |
7BBD
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![BU of 7bbd by Molmil](/molmil-images/mine/7bbd) | Crystal structure of monoubiquitinated TRIM21 RING (Ub-RING) In complex with ubiquitin charged Ube2N (Ube2N~Ub) and Ube2V2 | 分子名称: | Polyubiquitin-B,E3 ubiquitin-protein ligase TRIM21, Polyubiquitin-C, Ubiquitin-conjugating enzyme E2 N, ... | 著者 | Kiss, L, Neuhaus, D, James, L.C. | 登録日 | 2020-12-17 | 公開日 | 2021-01-27 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | RING domains act as both substrate and enzyme in a catalytic arrangement to drive self-anchored ubiquitination. Nat Commun, 12, 2021
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2O6V
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2XEW
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![BU of 2xew by Molmil](/molmil-images/mine/2xew) | Crystal structure of K11-linked diubiquitin | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, CITRATE ANION, ... | 著者 | Bremm, A, Freund, S.M.V, Komander, D. | 登録日 | 2010-05-18 | 公開日 | 2010-07-14 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Lys11-Linked Ubiquitin Chains Adopt Compact Conformations and are Preferentially Hydrolyzed by the Deubiquitinase Cezanne Nat.Struct.Mol.Biol., 17, 2010
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2IBI
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![BU of 2ibi by Molmil](/molmil-images/mine/2ibi) | Covalent Ubiquitin-USP2 Complex | 分子名称: | ETHANAMINE, Ubiquitin, Ubiquitin carboxyl-terminal hydrolase 2, ... | 著者 | Walker, J.R, Avvakumov, G.V, Bernstein, G, Xue, S, Finerty Jr, P.J, MacKenzie, F, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | 登録日 | 2006-09-11 | 公開日 | 2006-10-24 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Covalent Ubiquitin-USP2 Complex To be Published
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7M4O
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![BU of 7m4o by Molmil](/molmil-images/mine/7m4o) | |
6RYA
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![BU of 6rya by Molmil](/molmil-images/mine/6rya) | |
5AIU
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![BU of 5aiu by Molmil](/molmil-images/mine/5aiu) | A complex of RNF4-RING domain, Ubc13-Ub (isopeptide crosslink) | 分子名称: | 1,2-ETHANEDIOL, E3 UBIQUITIN-PROTEIN LIGASE RNF4, POLYUBIQUITIN-C, ... | 著者 | Branigan, E, Naismith, J.H. | 登録日 | 2015-02-17 | 公開日 | 2015-07-08 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | Structural Basis for the Ring Catalyzed Synthesis of K63 Linked Ubiquitin Chains Nat.Struct.Mol.Biol., 22, 2015
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4AP4
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![BU of 4ap4 by Molmil](/molmil-images/mine/4ap4) | Rnf4 - ubch5a - ubiquitin heterotrimeric complex | 分子名称: | E3 UBIQUITIN LIGASE RNF4, UBIQUITIN C, UBIQUITIN-CONJUGATING ENZYME E2 D1, ... | 著者 | Plechanovova, A, Hay, R.T, Tatham, M.H, Jaffray, E, Naismith, J.H. | 登録日 | 2012-03-30 | 公開日 | 2012-07-25 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | Structure of a Ring E3 Ligase and Ubiquitin-Loaded E2 Primed for Catalysis Nature, 489, 2012
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3ZNI
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![BU of 3zni by Molmil](/molmil-images/mine/3zni) | Structure of phosphoTyr363-Cbl-b - UbcH5B-Ub - ZAP-70 peptide complex | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, E3 UBIQUITIN-PROTEIN LIGASE CBL-B, ... | 著者 | Dou, H, Buetow, L, Sibbet, G.J, Cameron, K, Huang, D.T. | 登録日 | 2013-02-14 | 公開日 | 2013-07-10 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | Essentiality of a Non-Ring Element in Priming Donor Ubiquitin for Catalysis by a Monomeric E3. Nat.Struct.Mol.Biol., 20, 2013
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