7M4O

Crystal structure of phosphorylated RBR E3 ligase RNF216 in complex with K63-linked di-ubiquitin

Summary for 7M4O

Entry DOI	10.2210/pdb7m4o/pdb
Descriptor	E3 ubiquitin-protein ligase RNF216, Ubiquitin, ZINC ION, ... (7 entities in total)
Functional Keywords	e3 ligase, rbr, ubiquitin, enzyme, ligase
Biological source	Homo sapiens (Human) More
Total number of polymer chains	3
Total formula weight	33888.45
Authors	Cotton, T.R.,Lechtenberg, B.C. (deposition date: 2021-03-21, release date: 2022-01-05, Last modification date: 2023-10-18)
Primary citation	Cotton, T.R.,Cobbold, S.A.,Bernardini, J.P.,Richardson, L.W.,Wang, X.S.,Lechtenberg, B.C. Structural basis of K63-ubiquitin chain formation by the Gordon-Holmes syndrome RBR E3 ubiquitin ligase RNF216. Mol.Cell, 82:598-615.e8, 2022 Cited by PubMed: 34998453 DOI: 10.1016/j.molcel.2021.12.005 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.21 Å)

Structure validation