7M4O
Crystal structure of phosphorylated RBR E3 ligase RNF216 in complex with K63-linked di-ubiquitin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | E3 ubiquitin-protein ligase RNF216 | polymer | 138 | 15853.9 | 1 | UniProt (Q9NWF9) Pfam (PF26200) | Homo sapiens (Human) | RING finger protein 216,RING-type E3 ubiquitin transferase RNF216,Triad domain-containing protein 3,Ubiquitin-conjugating enzyme 7-interacting protein 1,Zinc finger protein inhibiting NF-kappa-B |
| 2 | B, C (B, C) | Ubiquitin | polymer | 76 | 8576.8 | 2 | UniProt (P0CG48) Pfam (PF00240) | Homo sapiens (Human) | |
| 3 | D, E, F (A) | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) | |||
| 4 | G, I, M (A, B, C) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 5 | H, K, L (A, B) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 6 | J (B) | 2-(2-METHOXYETHOXY)ETHANOL | non-polymer | 120.1 | 1 | Chemie (PG0) | |||
| 7 | N, O, P (A, B, C) | water | water | 18.0 | 81 | Chemie (HOH) |
Sequence modifications
A: 649 - 784 (UniProt: Q9NWF9)
| PDB | External Database | Details |
|---|---|---|
| Gly 647 | - | expression tag |
| Pro 648 | - | expression tag |
| Ala 688 | Cys 688 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 33007.6 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 880.8 | |
| All* | Total formula weight | 33888.4 |
