6QZP
 
 | | High-resolution cryo-EM structure of the human 80S ribosome | | 分子名称: | (3beta)-O~3~-[(2R)-2,6-dihydroxy-2-(2-methoxy-2-oxoethyl)-6-methylheptanoyl]cephalotaxine, 18S rRNA (1740-MER), 28S rRNA (3773-MER), ... | | 著者 | Natchiar, S.K, Myasnikov, A.G, Kratzat, H, Hazemann, I, Klaholz, B.P. | | 登録日 | 2019-03-12 | | 公開日 | 2019-04-24 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Visualization of chemical modifications in the human 80S ribosome structure.
Nature, 551, 2017
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8OJ5
 | | 60S ribosomal subunit bound to the E3-UFM1 complex - state 3 (in-vitro reconstitution) | | 分子名称: | 28S rRNA, 5.8S rRNA, 5S rRNA, ... | | 著者 | Penchev, I, DaRosa, P.A, Peter, J.J, Kulathu, Y, Becker, T, Beckmann, R, Kopito, R. | | 登録日 | 2023-03-23 | | 公開日 | 2024-02-21 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | UFM1 E3 ligase promotes recycling of 60S ribosomal subunits from the ER.
Nature, 627, 2024
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8FL0
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8G61
 | | mRNA decoding in human is kinetically and structurally distinct from bacteria (AC state) | | 分子名称: | 1,4-DIAMINOBUTANE, 18S rRNA, 28S rRNA, ... | | 著者 | Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Altman, R.B, Blanchard, S.C. | | 登録日 | 2023-02-14 | | 公開日 | 2023-04-19 | | 最終更新日 | 2023-11-15 | | 実験手法 | ELECTRON MICROSCOPY (2.94 Å) | | 主引用文献 | mRNA decoding in human is kinetically and structurally distinct from bacteria.
Nature, 617, 2023
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8XSY
 | | Cryo-EM structure of the human 80S ribosome with Tigecycline, e-tRNA and CCDC124 (40S head Swivelled) | | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | | 著者 | Li, X, Wang, M, Cheng, J. | | 登録日 | 2024-01-10 | | 公開日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline.
Nat Commun, 15, 2024
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6ZME
 | | SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-eERF1 ribosome complex | | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | | 著者 | Thoms, M, Buschauer, R, Ameismeier, M, Denk, T, Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. | | 登録日 | 2020-07-02 | | 公開日 | 2020-08-12 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2.
Science, 369, 2020
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8IDY
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8INF
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6Z6L
 | | Cryo-EM structure of human CCDC124 bound to 80S ribosomes | | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | | 著者 | Wells, J.N, Buschauer, R, Mackens-Kiani, T, Best, K, Kratzat, H, Berninghausen, O, Becker, T, Cheng, J, Beckmann, R. | | 登録日 | 2020-05-28 | | 公開日 | 2020-07-29 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structure and function of yeast Lso2 and human CCDC124 bound to hibernating ribosomes.
Plos Biol., 18, 2020
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6Y2L
 | | Structure of human ribosome in POST state | | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, ... | | 著者 | Bhaskar, V, Schenk, A.D, Cavadini, S, von Loeffelholz, O, Natchiar, S.K, Klaholz, B.P, Chao, J.A. | | 登録日 | 2020-02-16 | | 公開日 | 2020-04-15 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Dynamics of uS19 C-Terminal Tail during the Translation Elongation Cycle in Human Ribosomes.
Cell Rep, 31, 2020
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8FKZ
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6LQM
 | | Cryo-EM structure of a pre-60S ribosomal subunit - state C | | 分子名称: | 28S rRNA, 5.8S rRNA, 5S rRNA, ... | | 著者 | Liang, X, Zuo, M, Zhang, Y, Li, N, Ma, C, Dong, M, Gao, N. | | 登録日 | 2020-01-14 | | 公開日 | 2020-08-26 | | 実験手法 | ELECTRON MICROSCOPY (3.09 Å) | | 主引用文献 | Structural snapshots of human pre-60S ribosomal particles before and after nuclear export.
Nat Commun, 11, 2020
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6OM0
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6OLE
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6ZMO
 | | SARS-CoV-2 Nsp1 bound to the human LYAR-80S-eEF1a ribosome complex | | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | | 著者 | Thoms, M, Buschauer, R, Ameismeier, M, Denk, T, Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. | | 登録日 | 2020-07-03 | | 公開日 | 2020-08-19 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2.
Science, 369, 2020
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8OHD
 | | 60S ribosomal subunit bound to the E3-UFM1 complex - state 3 (native) | | 分子名称: | 28S rRNA, 5.8S rRNA, 5S rRNA, ... | | 著者 | Penchev, I, DaRosa, P.A, Becker, T, Beckmann, R, Kopito, R. | | 登録日 | 2023-03-21 | | 公開日 | 2024-02-21 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | UFM1 E3 ligase promotes recycling of 60S ribosomal subunits from the ER.
Nature, 627, 2024
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6Z6M
 | | Cryo-EM structure of human 80S ribosomes bound to EBP1, eEF2 and SERBP1 | | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | | 著者 | Wells, J.N, Buschauer, R, Mackens-Kiani, T, Best, K, Kratzat, H, Berninghausen, O, Becker, T, Cheng, J, Beckmann, R. | | 登録日 | 2020-05-28 | | 公開日 | 2020-07-29 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structure and function of yeast Lso2 and human CCDC124 bound to hibernating ribosomes.
Plos Biol., 18, 2020
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6LSR
 | | Cryo-EM structure of a pre-60S ribosomal subunit - state B | | 分子名称: | 28S rRNA, 5.8S rRNA, 5S rRNA, ... | | 著者 | Liang, X, Zuo, M, Zhang, Y, Li, N, Ma, C, Dong, M, Gao, N. | | 登録日 | 2020-01-20 | | 公開日 | 2020-08-26 | | 実験手法 | ELECTRON MICROSCOPY (3.13 Å) | | 主引用文献 | Structural snapshots of human pre-60S ribosomal particles before and after nuclear export.
Nat Commun, 11, 2020
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6LU8
 | | Cryo-EM structure of a human pre-60S ribosomal subunit - state A | | 分子名称: | 28S rRNA, 5.8S rRNA, 5S rRNA, ... | | 著者 | Liang, X, Zuo, M, Zhang, Y, Li, N, Ma, C, Dong, M, Gao, N. | | 登録日 | 2020-01-26 | | 公開日 | 2020-08-26 | | 実験手法 | ELECTRON MICROSCOPY (3.13 Å) | | 主引用文献 | Structural snapshots of human pre-60S ribosomal particles before and after nuclear export.
Nat Commun, 11, 2020
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8XSZ
 | | Cryo-EM structure of the human 80S ribosome with Tigecycline, E-tRNA and P-tRNA | | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | | 著者 | Li, X, Wang, M, Cheng, J. | | 登録日 | 2024-01-10 | | 公開日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline.
Nat Commun, 15, 2024
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6Y0G
 | | Structure of human ribosome in classical-PRE state | | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, ... | | 著者 | Bhaskar, V, Schenk, A.D, Cavadini, S, von Loeffelholz, O, Natchiar, S.K, Klaholz, B.P, Chao, J.A. | | 登録日 | 2020-02-07 | | 公開日 | 2020-04-15 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Dynamics of uS19 C-Terminal Tail during the Translation Elongation Cycle in Human Ribosomes.
Cell Rep, 31, 2020
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8INK
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8INE
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8IPY
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8IPD
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