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PDB: 21 件
6S9K
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BU of 6s9k by Molmil
Structure of 14-3-3 gamma in complex with caspase-2 peptide containing 14-3-3 binding motif Ser139 and NLS
分子名称: 1,1,1,3,3,3-hexafluoropropan-2-ol, 14-3-3 protein gamma, Caspase-2
著者Alblova, M, Obsil, T, Obsilova, V.
登録日2019-07-15
公開日2020-01-22
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献14-3-3 protein binding blocks the dimerization interface of caspase-2.
Febs J., 287, 2020
6ZBT
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BU of 6zbt by Molmil
Structure of 14-3-3 gamma in complex with Nedd4-2 14-3-3 binding motif Ser342
分子名称: 1,1,1,3,3,3-hexafluoropropan-2-ol, 14-3-3 protein gamma, E3 ubiquitin-protein ligase NEDD4-like
著者Joshi, R, Kalabova, D, Obsil, T, Obsilova, V.
登録日2020-06-09
公開日2021-07-21
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.79948521 Å)
主引用文献14-3-3-protein regulates Nedd4-2 by modulating interactions between HECT and WW domains.
Commun Biol, 4, 2021
3UZD
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BU of 3uzd by Molmil
Crystal structure of 14-3-3 GAMMA
分子名称: 14-3-3 protein gamma, Histone deacetylase 4, MAGNESIUM ION, ...
著者Xu, C, Bian, C, MacKenzie, F, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2011-12-07
公開日2012-03-21
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Sequence-Specific Recognition of a PxLPxI/L Motif by an Ankyrin Repeat Tumbler Lock.
Sci.Signal., 5, 2012
6ZC9
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BU of 6zc9 by Molmil
Structure of 14-3-3 gamma in complex with Nedd4-2 14-3-3 binding motif Ser448
分子名称: 1,1,1,3,3,3-hexafluoropropan-2-ol, 14-3-3 protein gamma, E3 ubiquitin-protein ligase NEDD4-like
著者Pohl, P, Kalabova, D, Obsil, T, Obsilova, V.
登録日2020-06-10
公開日2021-07-21
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.89895988 Å)
主引用文献14-3-3-protein regulates Nedd4-2 by modulating interactions between HECT and WW domains.
Commun Biol, 4, 2021
6A5S
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BU of 6a5s by Molmil
Structure of 14-3-3 gamma in complex with TFEB 14-3-3 binding motif
分子名称: 14-3-3 protein gamma, MAGNESIUM ION, SODIUM ION, ...
著者Xu, Y, Ren, J.Q, Feng, W.
登録日2018-06-25
公開日2019-02-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.099 Å)
主引用文献YWHA/14-3-3 proteins recognize phosphorylated TFEB by a noncanonical mode for controlling TFEB cytoplasmic localization.
Autophagy, 15, 2019
4E2E
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BU of 4e2e by Molmil
Crystal structure of a tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide (YWHAG) from Homo sapiens at 2.25 A resolution
分子名称: 1,2-ETHANEDIOL, 14-3-3 protein gamma
著者Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL)
登録日2012-03-08
公開日2012-03-21
最終更新日2023-02-01
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Crystal structure of a tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activa tion protein, gamma polypeptide (YWHAG) from Homo sapiens at 2.25 A resolution
To be published
7A6Y
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BU of 7a6y by Molmil
Structure of 14-3-3 gamma in complex with DAPK2 peptide stabilized by FC-A
分子名称: 14-3-3 protein gamma, DAPK2 C-terminal peptide, FUSICOCCIN
著者Horvath, M, Obsilova, V, Obsil, T.
登録日2020-08-27
公開日2021-08-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献14-3-3 proteins inactivate DAPK2 by promoting its dimerization and protecting key regulatory phosphosites.
Commun Biol, 4, 2021
2B05
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BU of 2b05 by Molmil
Crystal Structure of 14-3-3 gamma in complex with a phosphoserine peptide
分子名称: 14-3-3 protein gamma, peptide
著者Papagrigoriou, E, Elkins, J, Arrowsmith, C, Zhao, Y, Debreczeni, E.J, Edwards, A, Weigelt, J, Doyle, D, von Delft, F, Turnbull, A, Yang, X.
登録日2005-09-13
公開日2005-10-11
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Crystal Structure of 14-3-3 gamma in complex with a phosphoserine peptide
TO BE PUBLISHED
6GKF
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BU of 6gkf by Molmil
Structure of 14-3-3 gamma in complex with caspase-2 14-3-3 binding motif Ser139
分子名称: 14-3-3 protein gamma, Caspase-2
著者Alblova, M, Obsil, T, Obsilova, V.
登録日2018-05-20
公開日2018-10-17
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.598 Å)
主引用文献14-3-3 protein masks the nuclear localization sequence of caspase-2.
FEBS J., 285, 2018
6BZD
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BU of 6bzd by Molmil
Structure of 14-3-3 gamma R57E mutant bound to GlcNAcylated peptide
分子名称: 14-3-3 protein gamma, 2-acetamido-2-deoxy-beta-D-glucopyranose, GlcNAcylated peptide
著者Schumacher, M.A.
登録日2017-12-22
公開日2018-05-09
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.67 Å)
主引用文献Structural basis of O-GlcNAc recognition by mammalian 14-3-3 proteins.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
7A6R
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BU of 7a6r by Molmil
Structure of 14-3-3 gamma in complex with DAPK2 peptide containing the 14-3-3 binding motif
分子名称: 14-3-3 protein gamma, DAPK2 C-terminal peptide
著者Horvath, M, Obsilova, V, Obsil, T.
登録日2020-08-26
公開日2021-08-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献14-3-3 proteins inactivate DAPK2 by promoting its dimerization and protecting key regulatory phosphosites.
Commun Biol, 4, 2021
5D3E
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BU of 5d3e by Molmil
Crystal structure of human 14-3-3 gamma in complex with CFTR R-domain peptide pS768-pS795
分子名称: 14-3-3 protein gamma, Cystic fibrosis transmembrane conductance regulator
著者Stevers, L.M, Leysen, S.F.R, Ottmann, C.
登録日2015-08-06
公開日2016-03-16
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Characterization and small-molecule stabilization of the multisite tandem binding between 14-3-3 and the R domain of CFTR.
Proc.Natl.Acad.Sci.USA, 113, 2016
6SAD
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BU of 6sad by Molmil
Structure of 14-3-3 gamma in complex with double phosphorylated caspase-2 peptide on Ser139 and Ser164
分子名称: 14-3-3 protein gamma, Caspase-2
著者Kalabova, D, Obsil, T, Obsilova, V.
登録日2019-07-16
公開日2020-01-22
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.753 Å)
主引用文献14-3-3 protein binding blocks the dimerization interface of caspase-2.
Febs J., 287, 2020
6FEL
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BU of 6fel by Molmil
Structure of 14-3-3 gamma in complex with CaMKK2 14-3-3 binding motif Ser511
分子名称: 14-3-3 protein gamma, Calcium/calmodulin-dependent protein kinase kinase 2
著者Lentini Santo, D, Obsilova, V, Obsil, T.
登録日2018-01-02
公開日2018-01-10
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.84 Å)
主引用文献14-3-3 protein directly interacts with the kinase domain of calcium/calmodulin-dependent protein kinase kinase (CaMKK2).
Biochim. Biophys. Acta, 1862, 2018
6GKG
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BU of 6gkg by Molmil
Structure of 14-3-3 gamma in complex with caspase-2 14-3-3 binding motif Ser164
分子名称: 14-3-3 protein gamma, Caspase-2
著者Alblova, M, Obsil, T, Obsilova, V.
登録日2018-05-20
公開日2018-10-17
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.847 Å)
主引用文献14-3-3 protein masks the nuclear localization sequence of caspase-2.
FEBS J., 285, 2018
4O46
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BU of 4o46 by Molmil
14-3-3-gamma in complex with influenza NS1 C-terminal tail phosphorylated at S228
分子名称: 14-3-3 protein gamma, Nonstructural protein 1, UNKNOWN ATOM OR ION, ...
著者Qin, S, Liu, Y, Tempel, W, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2013-12-18
公開日2014-04-30
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural basis for histone mimicry and hijacking of host proteins by influenza virus protein NS1.
Nat Commun, 5, 2014
6BYJ
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BU of 6byj by Molmil
Structure of human 14-3-3 gamma bound to O-GlcNAc peptide
分子名称: 14-3-3 protein gamma, 2-acetamido-2-deoxy-beta-D-glucopyranose, TSTTATPPVSQASSTTTSTW O-GlcNac peptide
著者Schumacher, M.A.
登録日2017-12-20
公開日2018-05-09
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural basis of O-GlcNAc recognition by mammalian 14-3-3 proteins.
Proc.Natl.Acad.Sci.USA, 115, 2018
6Y4K
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BU of 6y4k by Molmil
Crystal structure of human 14-3-3 gamma in complex with CaMKK2 14-3-3 binding motif Ser100 and Fusicoccin A
分子名称: 14-3-3 protein gamma, Calcium/calmodulin-dependent protein kinase kinase 2, FUSICOCCIN
著者Lentini Santo, D, Obsilova, V, Obsil, T.
登録日2020-02-21
公開日2021-01-27
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Stabilization of Protein-Protein Interactions between CaMKK2 and 14-3-3 by Fusicoccins.
Acs Chem.Biol., 15, 2020
6Y6B
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BU of 6y6b by Molmil
Crystal structure of human 14-3-3 gamma in complex with CaMKK2 14-3-3 binding motif Ser100 and 16-OMe-Fusicoccin H
分子名称: (2~{R},3~{S},4~{S},5~{R},6~{S})-2-(hydroxymethyl)-6-[[(1~{S},3~{R},6~{S},7~{S},8~{R},9~{R},10~{R},11~{R},14~{S})-14-(me thoxymethyl)-3,10-dimethyl-9-oxidanyl-6-propan-2-yl-8-tricyclo[9.3.0.0^{3,7}]tetradecanyl]oxy]oxane-3,4,5-triol, 14-3-3 protein gamma, Calcium/calmodulin-dependent protein kinase kinase 2
著者Lentini Santo, D, Obsilova, V, Obsil, T.
登録日2020-02-26
公開日2021-02-03
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.08 Å)
主引用文献Stabilization of Protein-Protein Interactions between CaMKK2 and 14-3-3 by Fusicoccins.
Acs Chem.Biol., 15, 2020
4J6S
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BU of 4j6s by Molmil
14-3-3gamma complexed with the N-terminal sequence of tyrosine hydroxylase (residues 1-43)
分子名称: 14-3-3 protein gamma, N-terminal motif of tyrosine hydroxylase
著者Mileni, M, Martinez, A, Stevens, R.C.
登録日2013-02-11
公開日2013-10-02
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.08 Å)
主引用文献The N-terminal sequence of tyrosine hydroxylase is a conformationally versatile motif that binds 14-3-3 proteins and membranes.
J.Mol.Biol., 426, 2014
6BYL
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BU of 6byl by Molmil
Structure of 14-3-3 gamma bound to O-GlcNAcylated thr peptide
分子名称: 14-3-3 protein gamma, 2-acetamido-2-deoxy-beta-D-glucopyranose, TSASTTVPVTTATTTTTSTW O-GlcNac peptide
著者Schumacher, M.A.
登録日2017-12-20
公開日2018-05-09
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.35 Å)
主引用文献Structural basis of O-GlcNAc recognition by mammalian 14-3-3 proteins.
Proc.Natl.Acad.Sci.USA, 115, 2018

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